Presentation

Our group performs research into the design and synthesis of small molecules for application to various fields linked to biology:

• Imaging biological phenomena in the living animal (bio-activatable MRI contrast agents and bio-activated fluorogenic probes projects) for fundamental research, the development of diagnostic tools and for the evaluation of the success of therapeutic measures.
• Imaging biological phenomena in vitro (fluorogenic probes project) for potential applications to biotechnology (high throughput screening of bacterial colonies to detect the expression of specific peptidases) or to fluorescence microscopy.
• Exploitation of the N->CO interaction for the conception of protease inhibitors (in particular HIV-1 protease).

Although the the group's skills and experience are firmly anchored in organic synthesis, our research always lies at the interface of biology, imaging techniques and coordination chemistry. The Bio-Organic Chemistry group has been led by Principal Investigator Prof. Jens Hasserodt since its foundation in 2002.

Group Photo 2011

Our group is composed of: Professor Jens Hasserodt, Associate Professor Philippe Maurin, ATER Benjamin Bourdon, Doctoral students Jacek Kolanowski, Oliver Thorn-Seshold, Fayçal Touti, Guillaume Gros, Maxime Prost, and Jinping Wang.