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We are interested in understanding the role of conserved chromatin marks in the maintenance of germline identity and the response to environmental stress. To adress these questions, we are using C. elegans as a model organism. We use a combination of genetic, biochemical and genome wide approaches.
Chromatin regulation and germline development

Role of SET-2 dependent methylation in maintaining germline identity across generations? Identification and analysis of SET-2/SET1 associated proteins

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Chromatin and the response to environmental stress

Cellular adaptation to environmental changes relies on a wide range of regulatory mechanisms

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