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Article Reference Modeling Edar expression reveals the hidden dynamics of tooth signaling center patterning
Article Reference Programmed genome rearrangements: in lampreys, all cells are not equal.
How can organisms silence deleterious gene loci? A recent study has shed light on a very brute mechanism in a jawless vertebrate: the irreversible deletion of ...
Article Reference International Union of Pharmacology. LXVI. Orphan nuclear receptors.
Half of the members of the nuclear receptors superfamily are so-called "orphan" receptors because the identity of their ligand, if any, is unknown. Because of ...
Article Reference The ectodysplasin pathway: from diseases to adaptations.
The ectodysplasin (EDA) pathway, which is active during the development of ectodermal organs, including teeth, hairs, feathers, and mammary glands, and which ...
Article Reference The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death.
Ectodysplasin receptor EDAR is seen as a typical Tumor Necrosis Factor receptor (TNFR) family member known to interact with its ligand Eda-A1, and signaling ...
Article Reference Developmental and comparative transcriptomic identification of iridophore contribution to white barring in clownfish.
Actinopterygian fishes harbor at least eight distinct pigment cell types, leading to a fascinating diversity of colors. Among this diversity, the cellular ...
Article Reference Genome-wide in silico identification of new conserved and functional retinoic acid receptor response elements (direct repeats separated by 5 bp).
The nuclear retinoic acid receptors interact with specific retinoic acid (RA) response elements (RAREs) located in the promoters of target genes to orchestrate ...
Article Reference RAR/RXR binding dynamics distinguish pluripotency from differentiation associated cis-regulatory elements.
In mouse embryonic cells, ligand-activated retinoic acid receptors (RARs) play akey role in inhibiting pluripotency-maintaining genes and activating some major ...
Article Reference RAR/RXR binding dynamics distinguish pluripotency from differentiation associated cis-regulatory elements.
In mouse embryonic cells, ligand-activated retinoic acid receptors (RARs) play akey role in inhibiting pluripotency-maintaining genes and activating some major ...