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BIOL5105 : Relations hôte / microorganismes

Host and microbes

Niveau M2

Discipline(s) Biologie

ECTS 6.00

Période 1e semestre

Localisation Site Monod

Année 2021-2022

 Public externe (ouverts aux auditeurs de cours)

Mardi Matin
Mardi Après-midi
Mercredi Matin
Mercredi Après-midi
Jeudi Matin
Jeudi Après-midi
Vendredi Matin
Vendredi Après-midi
Horaires du cours
De 8h à 12h15 et de 14h30 à 16h30
Objectif du cours

Responsables : François Vandenesch (PU-PH UCBL) et Chloé Journo (MCU ENS)

Summary and Goals:

This course aims to provide students with an interdisciplinary understanding of the field of microbe / host interactions. Recent conceptual advances as well as innovative methodological approaches will be discussed and illustrated on specific examples from the bacteriology and virology disciplines. The program is designed to satisfy the scientific curiosity of students with molecular and cellular biology backgrounds, as well as students with evolution and ecology backgrounds. The program should allow rich interactions among students and between students and speakers.  


Topics (content may vary according to years):

Host / microbes interactions at the molecular and cellular levels

  • Mechanisms of microbial entry into host cells
  • Mechanisms of intracellular trafficking of microbes
  • Infections in the central nervous system 
  • Microbes & immunity


Host / microbiota interactions


Microbial evolution; modelling and predictions in microbiology 

  • Microbial evolution and emergence
  • Microbe / host coevolution
  • Paleomicrobiology
  • Systems biology of antimicrobial resistance


Host / microbes interactions and ecology

  • Impact of global changes in host / microbes interactions


Objectives and skills:

At the end of the course, students should be able to:

  • Follow with ease high-level scientific conferences from the field of host / microbes interactions.
  • Connect data from distinct conferences and students’ talks to build a comprehensive synthesis of the topic. 
  • Write a discussion on transversal questions, including methodological aspects.
  • Orally present recent data from the field, and place these data in a more general context.
  • Interact constructively with speakers and fellow students.


This course is designed in the continuity of the L3 “Microbes et Infections” and M1 “Microbiologie Moléculaire et Structurale” courses. However, students with other backgrounds, and in particular evolution and ecology backgrounds, are encouraged to join. 

Course organization

Each day, the course will host 2 or 3 speakers for approx. 1-hour talks, followed by discussions with the students. The speakers will be introduced by students.

Students will also prepare students’ talks during which they will present a recent article from the field. A wide range of topics covered by the articles will be offered, so that each student can choose a topic of interest. 


  • Students’ talk and participation to the discussions (40%)
  • Written exam (2h) (60%)

Du jeudi 28 novembre au vendredi 5 décembre 2021 (férie le lundi 1er novembre)


Modifié le :
19/07/2021 14:23:11