Teva VERNOUX
teva.vernoux
(33) 4 72 72 86 01
DR CNRS
Publications
Pradeep DAS
pradeep.das
(33) 4 72 72 89 37
MC ENS
Fabrice BESNARD
fabrice.besnard
(33) 4 72 72 89 82
CR INRAe
Publications
Yoan COUDERT
yoan.coudert
(33) 4 72 72 89 82
CR CNRS
Publications
Géraldine BRUNOUD
geraldine.brunoud
(33) 4 72 72 86 04
IR CNRS
Publications
Jonathan LEGRAND
jonathan.legrand
(33)4 72 72 86 04
IR CNRS
Publications
Stéphanie HALLET
stephanie.hallet
(33) 4 72 72 86 03
TR INRAe
Carlos GALVAN-AMPUDIA
carlos.galvan-ampudia
(33) 4 72 72 86 14
IR CNRS
Clement CHAMPION
clement.champion
Post-Doctorant
Hugo CAUMON
hugo.caumon
Doctorant
Jeanne ABITBOL-SPANGARO
jeanne.abitbolspangaro
Thèse
Landry DUGUET
landry.duguet
Thèse
Laure MANCINI
laure.mancini
Post-Doc
Priyanka PATRA
priyanka.patra
Thèse
Raquel MARTIN
raquel.martin
(33) 4 72 72 86 06
Post-Doc CNRS
2024
Journal articles
- titre
- The first intron of ARF7 is required for expression in root tips
- auteur
- Jingyi Han, Thomas Welch, Ute Voß, Teva Vernoux, Rahul Bhosale, Anthony Bishopp
- article
- iScience, 2024, 27 (6), pp.109936. ⟨10.1016/j.isci.2024.109936⟩
- Accès au texte intégral et bibtex
- titre
- A quantitative gibberellin signaling biosensor reveals a role for gibberellins in internode specification at the shoot apical meristem
- auteur
- Bihai Shi, Amelia Felipo Benavent, Guillaume Cerutti, Carlos Galvan-Ampudia, Lucas Jilli, Geraldine Brunoud, Jérôme Mutterer, Elody Vallet, Lali Sakvarelidze-Achard, Jean-Michel Davière, Alejandro Navarro-Galiano, Ankit Walia, Shani Lazary, Jonathan Legrand, Roy Weinstain, Alexander M. Jones, Salomé Prat, Patrick Achard, Teva Vernoux
- article
- Nature Communications, 2024, 15 (1), pp.3895. ⟨10.1038/s41467-024-48116-4⟩
- Accès au texte intégral et bibtex
- titre
- Re-examining meristems through the lens of evo-devo
- auteur
- Moïra Arnoux-Courseaux, Yoan Coudert
- article
- Trends in Plant Science, 2024, 29 (4), pp.413-427. ⟨10.1016/j.tplants.2023.11.003⟩
- Accès au texte intégral et bibtex
Preprints, Working Papers, ...
- titre
- ROS responsive Aux/IAA multimerization modulates auxin responses
- auteur
- Dipan Roy, Poonam Mehra, Vaishnavi Mukkawar, Lisa Clark, Kevin Bellande, Joop Em Vermeer, Raquel Martin Arevallilo, Teva Vernoux, Kawinnat Sue Ob, Andrew Jones, Ulrike Bechtold, Phil Mullineaux, Kathryn Lilley, Adrian Brown, Malcolm Bennett, Ari Sadanandom
- article
- 2024
- Accès au bibtex
2023
Journal articles
- titre
- Multi-Knock—a multi-targeted genome-scale CRISPR toolbox to overcome functional redundancy in plants
- auteur
- Yangjie Hu, Priyanka Patra, Odelia Pisanty, Anat Shafir, Zeinu Mussa Belew, Jenia Binenbaum, Shir Ben Yaakov, Bihai Shi, Laurence Charrier, Gal Hyams, Yuqin Zhang, Maor Trabulsky, Omer Caldararu, Daniela Weiss, Christoph Crocoll, Adi Avni, Teva Vernoux, Markus Geisler, Hussam Hassan Nour-Eldin, Itay Mayrose, Eilon Shani
- article
- Nature Plants, In press, ⟨10.1038/s41477-023-01374-4⟩
- Accès au texte intégral et bibtex
- titre
- TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance
- auteur
- Jie Wang, Qihang Jiang, Roman Pleskot, Peter Grones, Elmehdi Bahafid, Grégoire Denay, Carlos Galván-Ampudia, Xiangyu Xu, Michael Vandorpe, Evelien Mylle, Ive de Smet, Teva Vernoux, Rüdiger Simon, Moritz Nowack, Daniel van Damme
- article
- EMBO Reports, 2023, 24 (9), pp.e54709. ⟨10.15252/embr.202254709⟩
- Accès au texte intégral et bibtex
- titre
- Decoding the Auxin Matrix: Auxin Biology Through the Eye of the Computer
- auteur
- Raquel Martin-Arevalillo, Teva Vernoux
- article
- Annual Review of Plant Biology, 2023, 74, pp.387-413. ⟨10.1146/annurev-arplant-102720-033523⟩
- Accès au texte intégral et bibtex
- titre
- A matter of time: auxin signaling dynamics and the regulation of auxin responses during plant development
- auteur
- Hugo Caumon, Teva Vernoux
- article
- Journal of Experimental Botany, In press, ⟨10.1093/jxb/erad132⟩
- Accès au texte intégral et bibtex
2022
Journal articles
- titre
- bHLH heterodimer complex variations regulate cell proliferation activity in the meristems of Arabidopsis thaliana
- auteur
- Eliana Mor, Markéta Pernisová, Max Minne, Guillaume Cerutti, Dagmar Ripper, Jonah Nolf, Jennifer Andres, Laura Ragni, Matias D Zurbriggen, Bert de Rybel, Teva Vernoux
- article
- iScience, 2022, 25 (11), pp.105364. ⟨10.1016/j.isci.2022.105364⟩
- Accès au texte intégral et bibtex
- titre
- Transcriptional reprogramming during floral fate acquisition
- auteur
- Antoine Larrieu, Géraldine Brunoud, Aurore Guérault, Stéphanie Lainé, Lauriane Hennet, Arnaud Stigliani, Iris Gildea, Jeremy Just, Ludivine Soubigou-Taconnat, Sandrine Balzergue, Brendan Davies, Enrico Scarpella, Ykä Helariutta, François Parcy, Teva Vernoux
- article
- iScience, 2022, 25 (7), pp.104683. ⟨10.1016/j.isci.2022.104683⟩
- Accès au texte intégral et bibtex
- titre
- Hormonal control of cell identity and growth in the shoot apical meristem
- auteur
- Bihai Shi, Teva Vernoux
- article
- Current Opinion in Plant Biology, 2022, 65, pp.102111. ⟨10.1016/j.pbi.2021.102111⟩
- Accès au texte intégral et bibtex
- titre
- Apical dominance control by TAR-YUC-mediated auxin biosynthesis is a deep homology of land plants
- auteur
- Mattias Thelander, Katarina Landberg, Arthur Muller, Gladys Cloarec, Nik Cunniffe, Stéphanie Huguet, Ludivine Soubigou-Taconnat, Véronique Brunaud, Yoan Coudert
- article
- Current Biology - CB, 2022, 32 (17), pp.P3838-3846.E5. ⟨10.1016/j.cub.2022.06.064⟩
- Accès au texte intégral et bibtex
- titre
- Imaging the living plant cell: from probes to quantification
- auteur
- Leia Colin, Raquel Martin-Arevalillo, Simone Bovio, Amélie Bauer, Teva Vernoux, Marie-Cécile Caillaud, Benoit Landrein, Yvon Jaillais
- article
- The Plant cell, 2022, 34 (1), pp.247-272. ⟨10.1093/plcell/koab237⟩
- Accès au texte intégral et bibtex
Book sections
- titre
- Callose Detection and Quantification at Plasmodesmata in Bryophytes
- auteur
- Arthur Muller, Tomomichi Fujita, Yoan Coudert
- article
- Plasmodesmata, 2457, Springer US, pp.177-187, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2132-5_11⟩
- Accès au texte intégral et bibtex
- titre
- Tracking intercellular movement of fluorescent proteins in bryophytes
- auteur
- Takumi Tomoi, Yoan Coudert, Tomomichi Fujita
- article
- Plasmodesmata, 2457, Springer US, pp.321-332, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2132-5_22⟩
- Accès au texte intégral et bibtex
Preprints, Working Papers, ...
- titre
- TPLATE complex dependent endocytosis is required for shoot apical meristem maintenance by attenuating CLAVATA1 signaling
- auteur
- Jie Wang, Qihang Jiang, Roman Pleskot, Peter Grones, Grégoire Denay, Carlos Galván-Ampudia, Elmehdi Bahafid, Xiangyu Xu, Michael Vandorpe, Evelien Mylle, Ive de Smet, Teva Vernoux, Rüdiger Simon, Moritz K Nowack, Daniel van Damme
- article
- 2022
- Accès au texte intégral et bibtex
- titre
- From Single Cells to Flowers – Biological Complexity Driving Plant Reproductive Development
- auteur
- Isabel Schwarz, Manuel Neumann, Rosario Vega, Xiaocai Xu, Letizia Cornaro, Lucia Colombo, Teva Vernoux, Jian Xu, Sebastian Marquardt, Kerstin Kaufmann
- article
- 2022
- Accès au texte intégral et bibtex
- titre
- Apical and basal auxin sources pattern shoot branching in a moss
- auteur
- Mattias Thelander, Katarina Landberg, Arthur Muller, Gladys Cloarec, Nik Cunniffe, Stéphanie Huguet, Ludivine Soubigou-Taconnat, Véronique Brunaud, Yoan Coudert
- article
- 2022
- Accès au texte intégral et bibtex
2021
Journal articles
- titre
- Leaf Morphogenesis: Insights From the Moss Physcomitrium patens
- auteur
- Wenye Lin, Ying Wang, Yoan Coudert, Daniel Kierzkowski
- article
- Frontiers in Plant Science, 2021, 12, ⟨10.3389/fpls.2021.736212⟩
- Accès au texte intégral et bibtex
- titre
- What shoots can teach about theories of plant form
- auteur
- Teva Vernoux, Fabrice Besnard, Christophe Godin
- article
- Nature Plants, 2021, 7 (6), pp.716-724. ⟨10.1038/s41477-021-00930-0⟩
- Accès au texte intégral et bibtex
- titre
- Auxin Does the SAMba: Auxin Signaling in the Shoot Apical Meristem
- auteur
- Teva Vernoux, Markéta Pernisová
- article
- Cold Spring Harbor Perspectives in Biology, 2021, 13 (12), pp.a039925. ⟨10.1101/cshperspect.a039925⟩
- Accès au texte intégral et bibtex
- titre
- A network of transcriptional repressors modulates auxin responses.
- auteur
- Jekaterina Truskina, Jingyi Han, Elina Chrysanthou, Carlos Galvan-Ampudia, Stéphanie Lainé, Geraldine Brunoud, Julien Macé, Simon Bellows, Jonathan Legrand, Anne-Maarit Bågman, Margot Smit, Ondrej Smetana, Arnaud Stigniani, Silvana Porco, Malcom J. Bennett, Ari Pekka Mähönen, Francois Parcy, Etienne Farcot, François Roudier, Siobhan M Brady, Anthony Bishopp, Teva Vernoux
- article
- Nature, 2021, 589 (7840), pp.116-119. ⟨10.1038/s41586-020-2940-2⟩
- Accès au texte intégral et bibtex
- titre
- Developmental roles of Auxin Binding Protein 1 in Arabidopsis thaliana
- auteur
- Zuzana Gelová, Michelle Gallei, Markéta Pernisová, Geraldine Brunoud, Xixi Zhang, Matouš Glanc, Lanxin Li, Jaroslav Michalko, Zlata Pavlovičová, Inge Verstraeten, Huibin Han, Jakub Hajný, Robert Hauschild, Milada Čovanová, Marta Zwiewka, Lukas Hoermayer, Matyáš Fendrych, Tongda Xu, Teva Vernoux, Jiří Friml
- article
- Plant Science, 2021, 303, pp.110750. ⟨10.1016/j.plantsci.2020.110750⟩
- Accès au texte intégral et bibtex
- titre
- Phyllotaxis from a Single Apical Cell
- auteur
- Elsa Véron, Teva Vernoux, Yoan Coudert
- article
- Trends in Plant Science, In press, 26 (2), pp.124-131. ⟨10.1016/j.tplants.2020.09.014⟩
- Accès au texte intégral et bibtex
Preprints, Working Papers, ...
- titre
- A quantitative gibberellin signalling biosensor reveals a role for gibberellins in internode specification at the shoot apical meristem
- auteur
- Teva Vernoux, Bihai Shi, Amelia Felipo-Benavent, Guillaume Cerutti, Carlos Galvan-Ampudia, Lucas Jilli, Geraldine Brunoud, Jérome Mutterer, Lali Sakvarelidze-Achard, Jean-Michel Davière, Alejandro Navarro-Galiano, Ankit Walia, Shani Lazary, Jonathan Legrand, Roy Weinstein, Alexander Jones, Salomé Prat, Patrick Achard
- article
- 2021
- Accès au bibtex
2020
Journal articles
- titre
- Temporal integration of auxin information for the regulation of patterning
- auteur
- Carlos Galvan-Ampudia, Guillaume Cerutti, Jonathan Legrand, Geraldine Brunoud, Raquel Martin Arevalillo, Romain Azaïs, Vincent Bayle, Steven Moussu, Christian Wenzl, Yvon Jaillais, Jan U Lohmann, Christophe Godin, Teva Vernoux
- article
- eLife, 2020, 9, ⟨10.7554/eLife.55832⟩
- Accès au texte intégral et bibtex
- titre
- Methods to Visualize Auxin and Cytokinin Signaling Activity in the Shoot Apical Meristem.
- auteur
- Geraldine Brunoud, Carlos Galvan-Ampudia, Teva Vernoux
- article
- Methods in Molecular Biology, 2020, 2094, pp.79-89. ⟨10.1007/978-1-0716-0183-9_9⟩
- Accès au texte intégral et bibtex
- titre
- Low Blue Light Enhances Phototropism by Releasing Cryptochrome1-Mediated Inhibition of PIF4 Expression.
- auteur
- Alessandra Boccaccini, Martina Legris, Johanna Krahmer, Laure Allenbach-Petrolati, Anupama Goyal, Carlos Galvan-Ampudia, Teva Vernoux, Elizabeth Karayekov, Jorge Casal, Christian Fankhauser
- article
- Plant Physiology, 2020, 183 (4), pp.1780-1793. ⟨10.1104/pp.20.00243⟩
- Accès au texte intégral et bibtex
2019
Journal articles
- titre
- WUSCHEL acts as an auxin response rheostat to maintain apical stem cells in Arabidopsis
- auteur
- Yanfei Ma, Andrej Miotk, Olga Ermakova, Christian Wenzl, Anna Medzihradszky, Christophe Gaillochet, Joachim Forner, Gözde Utan, Klaus Brackmann, Carlos Galvan-Ampudia, Teva Vernoux, Thomas Greb, Jan Lohmann
- article
- Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-13074-9⟩
- Accès au texte intégral et bibtex
- titre
- Design Principles of Branching Morphogenesis in Filamentous Organisms
- auteur
- Yoan Coudert, Steven Harris, Bénédicte Charrier
- article
- Current Biology - CB, 2019, 29 (21), pp.R1149 - R1162. ⟨10.1016/j.cub.2019.09.021⟩
- Accès au texte intégral et bibtex
- titre
- Evolution of the Auxin Response Factors from charophyte ancestors
- auteur
- Raquel Martin-Arevalillo, Emmanuel Thevenon, Fanny Jégu, Thomas Vinos-Poyo, Teva Vernoux, François Parcy, Renaud Dumas
- article
- PLoS Genetics, 2019, 15 (9), pp.e1008400. ⟨10.1371/journal.pgen.1008400⟩
- Accès au texte intégral et bibtex
- titre
- The RIN ‐regulated Small Auxin‐Up RNA SAUR 69 is involved in the unripe‐to‐ripe phase transition of tomato fruit via enhancement of the sensitivity to ethylene
- auteur
- Jun‐hye Shin, Isabelle Mila, Mingchun Liu, Maria Aurineide Rodrigues, Teva Vernoux, Julien Pirrello, Mondher Bouzayen
- article
- New Phytologist, 2019, 222 (2), pp.820-836. ⟨10.1111/nph.15618⟩
- Accès au bibtex
- titre
- Dissecting the pathways coordinating patterning and growth by plant boundary domains
- auteur
- Aude Maugarny-Calès, Millan Cortizo, Bernard B. Adroher, Néro N. Borrega, Beatriz Goncalves Gonçalves, Geraldine Brunoud, Teva Vernoux, Nicolas Arnaud, Patrick Laufs
- article
- PLoS Genetics, 2019, 15 (1), pp.e1007913. ⟨10.1371/journal.pgen.1007913⟩
- Accès au texte intégral et bibtex
- titre
- Reconstructing trait evolution in plant evo–devo studies
- auteur
- Pierre-Marc Delaux, Alexander Hetherington, Yoan Coudert, Charles Delwiche, Christophe Dunand, Sven Gould, Paul Kenrick, Fay-Wei Li, Herve Philippe, Stefan Rensing, Mélanie K Rich, Christine Strullu-Derrien, Jan de Vries
- article
- Current Biology - CB, 2019, 29 (21), pp.R1110-R1118. ⟨10.1016/j.cub.2019.09.044⟩
- Accès au texte intégral et bibtex
- titre
- Capturing Auxin Response Factors Syntax Using DNA Binding Models
- auteur
- Arnaud Stigliani, Raquel Martin-Arevalillo, Jérémy Lucas, Adrien Bessy, Thomas Vinos-Poyo, Victoria Mironova, Teva Vernoux, Renaud Dumas, François Parcy
- article
- Molecular Plant, 2019, 12 (6), pp.822-832. ⟨10.1016/j.molp.2018.09.010⟩
- Accès au texte intégral et bibtex
- titre
- Shining light on plant hormones with genetically encoded biosensors
- auteur
- Raquel Martin Arevalillo, Teva Vernoux
- article
- Biological Chemistry, 2019, 400 (4), pp.477-486. ⟨10.1515/hsz-2018-0310⟩
- Accès au bibtex
Book sections
- titre
- Patterning at the shoot apical meristem and phyllotaxis
- auteur
- Teva Vernoux, Shi Bihai
- article
- Current Topics in Developmental Biology, 131, Elsevier Academic Press Inc., 11 p., 2019, Current Topics in Developmental Biology, 978-0-12-809804-2. ⟨10.1016/bs.ctdb.2018.10.003⟩
- Accès au bibtex
2018
Journal articles
- titre
- Root branching toward water involves posttranslational modification of transcription factor ARF7
- auteur
- Beatriz Orosa-Puente, Nicola Leftley, Daniel von Wangenheim, Jason Banda, Anjil Srivastava, Kristine Hill, Jekaterina Truskina, Rahul Bhosale, Emily Morris, Moumita Srivastava, Britta Kümpers, Tatsuaki Goh, Hidehiro Fukaki, Joop Vermeer, Teva Vernoux, José Dinneny, Andrew French, Anthony Bishopp, Ari Sadanandom, Malcolm Bennett
- article
- Science, 2018, 362 (6421), pp.1407-1410. ⟨10.1126/science.aau3956⟩
- Accès au bibtex
- titre
- A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate
- auteur
- Rahul Bhosale, Jitender Giri, Bipin Pandey, Ricardo Giehl, Anja Hartmann, Richard Traini, Jekaterina Truskina, Nicola Leftley, Meredith Hanlon, Kamal Swarup, Afaf Rashed, Ute Voss, Jose Alonso, Anna Stepanova, Jeonga Yun, Karin Ljung, Kathleen Brown, Jonathan P Lynch, Liam Dolan, Teva Vernoux, Anthony Bishopp, Darren Wells, Nicolaus von Wirén, Malcolm Bennett, Ranjan Swarup
- article
- Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-03851-3⟩
- Accès au texte intégral et bibtex
- titre
- Transcriptional induction of cell wall remodelling genes is coupled to microtubule-driven growth isotropy at the shoot apex in Arabidopsis
- auteur
- Alessia Armezzani, Ursula Abad, Olivier Ali, Amélie Andres Robin, Laetitia Vachez, Antoine Larrieu, Ewa Mellerowicz, Ludivine Taconnat, Virginie Battu, Thomas Stanislas, Mengying Liu, Teva Vernoux, Jan Traas, Massimiliano Sassi
- article
- Development (Cambridge, England), 2018, 145 (11), ⟨10.1242/dev.162255⟩
- Accès au texte intégral et bibtex
- titre
- The Rosa genome provides new insights into the domestication of modern roses
- auteur
- Olivier Raymond, Jerome Gouzy, Jérémy Just, Hélène Badouin, Marion Verdenaud, Arnaud Lemainque, Philippe Vergne, Sandrine Moja, Nathalie Choisne, Caroline C. Pont, Sébastien Carrere, Jean Claude Caissard, Arnaud Couloux, Ludovic Cottret, Jean-Marc Aury, Judit Szécsi, David D. Latrasse, Mohammed Madoui, Léa Francois, Xiaopeng Fu, Shu-Hua Yang, Annick Dubois, Florence Piola, Antoine Larrieu, Magali Perez, Karine Labadie, Lauriane Perrier, Benjamin Govetto, Yoan Labrousse, Priscilla Villand, Claudia Bardoux, Véronique Boltz, Celine Lopez-Roques, Pascal Heitzler, Teva Vernoux, Michiel Vandenbussche, Hadi Quesneville, Adnane Boualem, Abdelhafid Bendahmane, Chang Liu, Manuel Le Bris, Jérôme Salse, Sylvie Baudino, Moussa Benhamed, Patrick Wincker, Mohammed Bendahmane
- article
- Nature Genetics, 2018, 50 (6), pp.772-777. ⟨10.1038/s41588-018-0110-3⟩
- Accès au texte intégral et bibtex
- titre
- Systems biology of meristems: an interview with Teva Vernoux
- auteur
- Teva Vernoux
- article
- BMC Biology, 2018, 16, ⟨10.1186/s12915-018-0591-7⟩
- Accès au texte intégral et bibtex
- titre
- The growth of a stable stationary structure: coordinating cell behavior and patterning at the shoot apical meristem
- auteur
- Jekaterina Truskina, Teva Vernoux
- article
- Current Opinion in Plant Biology, 2018, 41, pp.83-88. ⟨10.1016/j.pbi.2017.09.011⟩
- Accès au bibtex
Preprints, Working Papers, ...
- titre
- From spatio-temporal morphogenetic gradients to rhythmic patterning at the shoot apex
- auteur
- Carlos Galvan-Ampudia, Guillaume Cerutti, Jonathan Legrand, Romain Azaïs, Geraldine Brunoud, Steven Moussu, Christian Wenzl, Jan U Lohmann, Christophe Godin, Teva Vernoux
- article
- 2018
- Accès au texte intégral et bibtex
2017
Journal articles
- titre
- Auxin 2016: a burst of auxin in the warm south of China
- auteur
- Teva Vernoux, Stephanie Robert
- article
- Development (Cambridge, England), 2017, 144 (4), pp.533-540. ⟨10.1242/dev.144790⟩
- Accès au bibtex
- titre
- Structure of the Arabidopsis TOPLESS corepressor provides insight into the evolution of transcriptional repression
- auteur
- Raquel Martin-Arevalillo, Max H. Nanao, Antoine Larrieu, Thomas Vinos-Poyo, David Mast, Carlos Galvan-Ampudia, Geraldine Brunoud, Teva Vernoux, Renaud Dumas, François Parcy
- article
- Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (30), pp.8107-8112. ⟨10.1073/pnas.1703054114⟩
- Accès au texte intégral et bibtex
2016
Journal articles
- titre
- A stochastic multicellular model identifies biological watermarks from disorders in self-organized patterns of phyllotaxis
- auteur
- Yassin Refahi, Géraldine Brunoud, Etienne Farcot, Alain Jean-Marie, Minna Pulkkinen, Teva Vernoux, Christophe Godin
- article
- eLife, 2016, 71, pp.50. ⟨10.7554/eLife.14093.001⟩
- Accès au texte intégral et bibtex
- titre
- A Glimpse beyond Structures in Auxin-Dependent Transcription.
- auteur
- François Parcy, Teva Vernoux, Renaud Dumas
- article
- Trends in Plant Science, 2016, 21 (7), pp.574-583. ⟨10.1016/j.tplants.2016.02.002⟩
- Accès au bibtex
- titre
- Modelling the influence of dimerisation sequence dissimilarities on the auxin signalling network
- auteur
- Jonathan Legrand, Jean-Benoist Leger, Stephane S. Robin, Teva Vernoux, Yann Guédon
- article
- BMC Systems Biology, 2016, 10 (22), pp.17. ⟨10.1186/s12918-016-0254-7⟩
- Accès au texte intégral et bibtex
- titre
- Phyllotaxis: from patterns of organogenesis at the meristem to shoot architecture
- auteur
- Carlos S Galvan-‐ampudia, Anaïs M Chaumeret, Christophe Godin, Teva Vernoux
- article
- Wiley Interdisciplinary Reviews: Developmental Biology, 2016, 5 (4), pp.460 - 473. ⟨10.1002/wdev.231⟩
- Accès au texte intégral et bibtex
- titre
- Reproductive failure in Arabidopsis thaliana under transient carbohydrate limitation: flowers and very young siliques are jettisoned and the meristem is maintained to allow successful resumption of reproductive growth
- auteur
- Martin A. Lauxmann, Maria G. Annunziata, Geraldine Brunoud, Vanessa Wahl, Andrzej Koczut, Asdrubal Burgos, Justyna J. Olas, Eugenia Maximova, Christin Abel, Armin Schlereth, Aleksandra M. Soja, Oliver E. Bläsing, John E. Lunn, Teva Vernoux, Mark Stitt
- article
- Plant, Cell and Environment, 2016, 39 (4), pp.745-767. ⟨10.1111/pce.12634⟩
- Accès au bibtex
- titre
- Q&A: How does jasmonate signaling enable plants to adapt and survive?
- auteur
- Antoine Larrieu, Teva Vernoux
- article
- BMC Biology, 2016, 14, pp.1-8. ⟨10.1186/s12915-016-0308-8⟩
- Accès au texte intégral et bibtex
Preprints, Working Papers, ...
- titre
- Semi-parametric Markov Tree for cell lineage analysis
- auteur
- Pierre Fernique, Jonathan Legrand, Jean-Baptiste Durand, Yann Guédon
- article
- 2016
- Accès au bibtex
2015
Journal articles
- titre
- Modeling plant development: from signals to gene networks
- auteur
- Cyril Lavedrine, Etienne Farcot, Teva Vernoux
- article
- Current Opinion in Plant Biology, 2015, 27, pp.148-153. ⟨10.1016/j.pbi.2015.07.002⟩
- Accès au bibtex
- titre
- Meristem size contributes to the robustness of phyllotaxis in Arabidopsis
- auteur
- Benoit Landrein, Yassin Refahi, Fabrice Besnard, Nathan Hervieux, Vincent Mirabet, Arezki Boudaoud, Teva Vernoux, Olivier O. Hamant
- article
- Journal of Experimental Botany, 2015, 66 (5), pp.1317-1324. ⟨10.1093/jxb/eru482⟩
- Accès au texte intégral et bibtex
- titre
- Three ancient hormonal cues co-ordinate shoot branching in a moss
- auteur
- Yoan Coudert, Wojtek Palubicki, Karin Ljung, Ondrej Novak, Ottoline Leyser, Jill Harrison
- article
- eLife, 2015
- Accès au texte intégral et bibtex
- titre
- Overexpression of the arabidopsis thaliana signalling peptide TAXIMIN1 affects lateral organ development
- auteur
- Janine Colling, Takayuki Tohge, Rebecca de Clercq, Geraldine Brunoud, Teva Vernoux, Alisdair Fernie, Nokwanda Makunga, Alain Goossens, Laurens Pauwels
- article
- Journal of Experimental Botany, 2015, 66 (17), pp.5337-5349. ⟨10.1093/jxb/erv291⟩
- Accès au bibtex
- titre
- Mechanical stress contributes to the expression of the STM homeobox gene in Arabidopsis shoot meristems
- auteur
- Benoit Landrein, Annamaria Kiss, Massimiliano Sassi, Aurélie Chauvet, Pradeep Das, Millan Cortizo Sabugo Cortizo, Patrick P. Laufs, Seiji Takeda, Mitsuhiro Aida, Jan Traas, Teva Vernoux, Arezki Boudaoud, Olivier O. Hamant
- article
- eLife, 2015, 4, pp.1-27. ⟨10.7554/eLife.07811⟩
- Accès au texte intégral et bibtex
- titre
- A modular analysis of the auxin signalling network
- auteur
- Etienne Farcot, Cyril Lavedrine, Teva Vernoux
- article
- PLoS ONE, 2015, 10 (3), ⟨10.1371/journal.pone.0122231⟩
- Accès au texte intégral et bibtex
- titre
- Transcriptional control of tissue formation throughout root development
- auteur
- Miguel A. Moreno-Risueno, Rosangela Sozzani, Galip Gürkan Yardimci, Jalean J. Petricka, Teva Vernoux, Ikram Blilou, Jose Alonso, Cara M. Winter, Uwe Ohler, Ben Scheres, Philip N. Benfey
- article
- Science, 2015, 350 (6259), pp.426-430. ⟨10.1126/science.aad1171⟩
- Accès au bibtex
- titre
- A fluorescent hormone biosensor reveals the dynamics of jasmonate signalling in plants
- auteur
- Antoine Larrieu, Antony Champion, Jonathan Legrand, Julien Lavenus, David Mast, Geraldine Brunoud, Jaesung Oh, Soazig Guyomarc'H, Maxime Pizot, Edward E. Farmer, Colin Turnbull, Teva Vernoux, Malcolm J. Bennett, Laurent Laplaze
- article
- Nature Communications, 2015, 6, pp.1-8. ⟨10.1038/ncomms7043⟩
- Accès au texte intégral et bibtex
- titre
- Reporters for sensitive and quantitative measurement of auxin response
- auteur
- Che-Yang Liao, Wouter Smet, Geraldine Brunoud, Saiko Yoshida, Teva Vernoux, Dolf Weijers
- article
- Nature Methods, 2015, 12 (3), ⟨10.1038/NMETH.3279⟩
- Accès au bibtex
Book sections
- titre
- Comparison of plant hormone signalling systems
- auteur
- Antoine Larrieu, Teva Vernoux
- article
- Plant Hormone Signalling, 58, Portland Press, pp.17, 2015, Essays in Biochemistry, ⟨10.1042/BSE0580165⟩
- Accès au bibtex
2014
Journal articles
- titre
- An Auxin-Mediated Shift toward Growth Isotropy Promotes Organ Formation at the Shoot Meristem in Arabidopsis
- auteur
- Massimiliano Sassi, Olivier Ali, Frédéric Boudon, Gladys Cloarec, Ursula Abad, Coralie Cellier, Xu Chen, Benjamin Gilles, Pascale Milani, Jìrí Friml, Teva Vernoux, Christophe Godin, Olivier Hamant, Jan Traas
- article
- Current Biology - CB, 2014, 24 (19), pp.2335-2342. ⟨10.1016/j.cub.2014.08.036⟩
- Accès au texte intégral et bibtex
- titre
- Auxin depletion from the leaf axil conditions competence for axillary meristem formation in Arabidopsis and tomato
- auteur
- Quan Wang, Wouter Kohlen, Susanne Rossmann, Teva Vernoux, Klaus Theres
- article
- The Plant cell, 2014, 26 (5), pp.2068-2079. ⟨10.1105/tpc.114.123059⟩
- Accès au texte intégral et bibtex
- titre
- Systems analysis of auxin transport in the Arabidopsis root apex
- auteur
- Leah R. Band, Darren M. Wells, John A. Fozard, Teodor Ghetiu, Andrew P. French, Michael P. Pound, Michael H. Wilson, Lei Yu, Wenda Li, Hussein I. Hijazi, Jaesung Oh, Simon P. Pearce, Miguel A. Perez-Amador, Jeonga Yun, Eric Kramer, Jose M. Alonso, Christophe Godin, Teva Vernoux, T. Charlie Hodgman, Tony P. Pridmore, Ranjan Swarup, John R. King, Malcolm J. Bennett
- article
- The Plant cell, 2014, 26 (3), pp.862-875. ⟨10.1105/tpc.113.119495⟩
- Accès au bibtex
- titre
- Signal integration by GSK3 kinases in the root
- auteur
- Carlos S. Galvan-Ampudia, Teva Vernoux
- article
- Nature Cell Biology, 2014, 16 (1), pp.21-23. ⟨10.1038/ncb2898⟩
- Accès au bibtex
- titre
- The AHP6 cytokinin signaling inhibitor mediates an auxin-cytokinin crosstalk that regulates the timing of organ initiation at the shoot apical meristem
- auteur
- Fabrice Besnard, Frédérique Rozier, Teva Vernoux
- article
- Plant Signaling and Behavior, 2014, 9 (4), ⟨10.4161/psb.28788⟩
- Accès au texte intégral et bibtex
- titre
- Structural basis for oligomerization of auxin transcriptional regulators.
- auteur
- Max H Nanao, Thomas Vinos-Poyo, Géraldine Brunoud, Emmanuel Thévenon, Meryl Mazzoleni, David Mast, Stéphanie Lainé, Shucai Wang, Gretchen Hagen, Hanbing Li, Thomas J Guilfoyle, François Parcy, Teva Vernoux, Renaud Dumas
- article
- Nature Communications, 2014, 5, pp.3617. ⟨10.1038/ncomms4617⟩
- Accès au texte intégral et bibtex
- titre
- Auxin depletion from leaf primordia contributes to organ patterning
- auteur
- Jiyan Qi, Ying Wang, Ting Yu, Alexandre Cunha, Binbin Wu, Teva Vernoux, Elliot Meyerowitz, Yuling Jiao
- article
- Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (52), pp.18769 - 18774. ⟨10.1073/pnas.1421878112⟩
- Accès au texte intégral et bibtex
- titre
- Plasma membrane H+-ATPase regulation is required for auxin gradient formation preceding phototropic growth
- auteur
- Tim Hohm, Emilie Demarsy, Clement Quan, Laure Allenbach Petrolati, Tobias Preuten, Teva Vernoux, Sven Bergmann, Christian Fankhauser
- article
- Molecular Systems Biology, 2014, 10 (9), pp.1-11. ⟨10.15252/msb.20145247⟩
- Accès au texte intégral et bibtex
- titre
- Analysis of 3D gene expression patterns in plants using whole-mount RNA in situ hybridization
- auteur
- Frédérique Rozier, Vincent Mirabet, Teva Vernoux, Pradeep Das
- article
- Nature Protocols, 2014, 9 (10), pp.2464-2475. ⟨10.1038/nprot.2014.162⟩
- Accès au bibtex
- titre
- Cytokinin signalling inhibitory fields provide robustness to phyllotaxis
- auteur
- Fabrice Besnard, Yassin Refahi, Valérie Morin, Benjamin Marteaux, Géraldine Brunoud, Pierre Chambrier, Frédérique Rozier, Vincent Mirabet, Jonathan Legrand, Stéphanie Lainé, Emmanuel Thévenon, Etienne Farcot, Coralie Cellier, Pradeep Das, Anthony Bishopp, Renaud Dumas, François Parcy, Ykä Helariutta, Arezki Boudaoud, Christophe Godin, Jan Traas, Yann Guédon, Teva Vernoux
- article
- Nature, 2014, 505 (7483), pp.417-421. ⟨10.1038/nature12791⟩
- Accès au bibtex
- titre
- Plant roots use a patterning mechanism to position lateral root branches toward available water
- auteur
- Yun Bao, Pooja Aggarwal, Neil E. Robbins, Craig J. Sturrock, Mark C. Thompson, Han Qi Tan, Cliff Tham, Lina Duan, Pedro L. Rodriguez, Teva Vernoux, Sacha J. Mooney, Malcolm J. Bennett, Jose R. Dinneny
- article
- Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (25), pp.9319-9324. ⟨10.1073/pnas.1400966111⟩
- Accès au texte intégral et bibtex
2013
Journal articles
- titre
- Auxin and self-organization at the shoot apical meristem
- auteur
- Massimiliano Sassi, Teva Vernoux
- article
- Journal of Experimental Botany, 2013, 64 (9), pp.2579 - 2592. ⟨10.1093/jxb/ert101⟩
- Accès au bibtex
- titre
- Biosensors for phytohormone quantification: challenges, solutions, and opportunities
- auteur
- Darren M. Wells, Laurent Laplaze, Malcolm J. Bennett, Teva Vernoux
- article
- Trends in Plant Science, 2013, 18 (5), pp.244 - 249. ⟨10.1016/j.tplants.2012.12.005⟩
- Accès au bibtex
- titre
- Halotropism Is a Response of Plant Roots to Avoid a Saline Environment
- auteur
- Carlos S. Galvan-Ampudia, Magdalena M. Julkowska, Essam Darwish, Jacinto Gandullo, Ruud A. Korver, Geraldine Brunoud, Michel A. Haring, Teun Munnik, Teva Vernoux, Christa Testerink
- article
- Current Biology - CB, 2013, 23 (20), pp.2044 - 2050. ⟨10.1016/j.cub.2013.08.042⟩
- Accès au bibtex
- titre
- Plant hormone signaling during development: insights from computational models
- auteur
- Marina Oliva, Etienne Farcot, Teva Vernoux
- article
- Current Opinion in Plant Biology, 2013, 16 (1), pp.19-24. ⟨10.1016/j.pbi.2012.11.006⟩
- Accès au texte intégral et bibtex
- titre
- Pattern identification and characterization reveal permutations of organs as a key genetically controlled property of post-meristematic phyllotaxis
- auteur
- Yann Guédon, Yassin Refahi, Fabrice Besnard, Etienne Farcot, Christophe Godin, Teva Vernoux
- article
- Journal of Theoretical Biology, 2013, 338, pp.94-110. ⟨10.1016/j.jtbi.2013.07.026⟩
- Accès au bibtex
2012
Journal articles
- titre
- A Light-Regulated Genetic Module Was Recruited to Carpel Development in Arabidopsis following a Structural Change to SPATULA
- auteur
- Matthieu Reymond, Geraldine Brunoud, Aurélie Chauvet, Jaime F. Martinez-Garcia, Marie-Laure Magniette, Françoise Monéger, C.P. Scutt
- article
- The Plant cell, 2012, 24 (7), pp.2812 - 2825. ⟨10.1105/tpc.112.097915⟩
- Accès au bibtex
- titre
- Root gravitropism is regulated by a transient lateral auxin gradient controlled by a tipping-point mechanism.
- auteur
- Leah R Band, Darren M Wells, Antoine Larrieu, Jianyong Sun, Alistair M Middleton, Andrew P French, Géraldine Brunoud, Ethel Mendocilla Sato, Michael H Wilson, Benjamin Péret, Marina Oliva, Ranjan Swarup, Ilkka Sairanen, Geraint Parry, Karin Ljung, Tom Beeckman, Jonathan M Garibaldi, Mark Estelle, Markus R Owen, Kris Vissenberg, T Charlie Hodgman, Tony P Pridmore, John R King, Teva Vernoux, Malcolm J Bennett
- article
- Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (12), pp.4668-73. ⟨10.1073/pnas.1201498109⟩
- Accès au bibtex
- titre
- COP1 mediates the coordination of root and shoot growth by light through modulation of PIN1-and PIN2-dependent auxin transport in Arabidopsis
- auteur
- Massimiliano Sassi, Yanfen Lu, Yonghong Zhang, Juan Wang, Pankaj Dhonukshe, Ikram Blilou, Minqiu Dai, Juan Li, Ximing Gong, Yvon Jaillais, Xuhong Yu, Jan Traas, Ida Ruberti, Haiyang Wang, Ben Scheres, Teva Vernoux, Jian Xu
- article
- Development (Cambridge, England), 2012, 139 (18), pp.3402 - 3412. ⟨10.1242/dev.078212⟩
- Accès au bibtex
- titre
- Modeling regulatory networks to understand plant development: small is beautiful
- auteur
- Alistair Middleton, Etienne Farcot, Markus Owen, Teva Vernoux
- article
- The Plant cell, 2012, 24 (10), pp.3876-3891. ⟨10.1105/tpc.112.101840⟩
- Accès au bibtex
- titre
- Noise and robustness in phyllotaxis
- auteur
- Vincent Mirabet, Fabrice Besnard, Teva Vernoux, Arezki Boudaoud
- article
- PLoS Computational Biology, 2012, 8 (2), ⟨10.1371/journal.pcbi.1002389⟩
- Accès au texte intégral et bibtex
- titre
- A novel sensor to map auxin response and distribution at high spatio-temporal resolution
- auteur
- Geraldine Brunoud, Darren M. Wells, Marina Oliva, Antoine Larrieu, Vincent Mirabet, Amy H. Burrow, Tom Beeckman, Stefan Kepinski, Jan Traas, Malcolm J. Bennett, Teva Vernoux
- article
- Nature, 2012, 482 (7383), pp.103 - U132. ⟨10.1038/nature10791⟩
- Accès au bibtex
2011
Journal articles
- titre
- The auxin signalling network translates dynamic input into robust patterning at the shoot apex
- auteur
- Teva Vernoux, Géraldine Brunoud, Etienne Farcot, Valérie Morin, Hilde van Den Daele, Jonathan Legrand, Marina Oliva, Pradeep Das, Antoine Larrieu, Darren Wells, Yann Guédon, Lynne Armitage, Franck Picard, Soazig Guyomarch, Coralie Cellier, Geraint Parry, Rachil Koumproglou, John H. Doonan, Mark Estelle, Christophe Godin, Stefan Kepinski, Malcolm Bennett, Lieven De Veylder, Jan Traas
- article
- Molecular Systems Biology, 2011, 7 (508), ⟨10.1038/msb.2011.39⟩
- Accès au texte intégral et bibtex
- titre
- Positional information by differential endocytosis splits auxin response to drive arabidopsis root meristem growth
- auteur
- Luca Santuari, Emanuele Scacchi, Antia Rodriguez-Villalon, Paula Salinas, Esther M. N. Dohmann, Geraldine Brunoud, Teva Vernoux, Richard S. Smith, Christian S. Hardtke
- article
- Current Biology - CB, 2011, 21 (22), pp.1918 - 1923. ⟨10.1016/j.cub.2011.10.002⟩
- Accès au bibtex
- titre
- Organogenesis from stem cells in planta: multiple feedback loops integrating molecular and mechanical signals
- auteur
- Fabrice Besnard, Teva Vernoux, Olivier O. Hamant
- article
- Cellular and Molecular Life Sciences, 2011, 68 (17), pp.2885-2906. ⟨10.1007/s00018-011-0732-4⟩
- Accès au bibtex
2010
Journal articles
- titre
- Interplay between the NADP-linked thioredoxin and glutathione systems in Arabidopsis auxin signaling.
- auteur
- Talaat Bashandy, Jocelyne Guilleminot, Teva Vernoux, David Caparros-Ruiz, Karin Ljung, Yves Meyer, Jean-Philippe Reichheld
- article
- The Plant cell, 2010, 22 (2), pp.376-91. ⟨10.1105/tpc.109.071225⟩
- Accès au bibtex
- titre
- Cyclin-dependent kinase activity maintains the shoot apical meristem cells in an undifferentiated state
- auteur
- Tarik Gaamouche, Carmem-Lara de O. Manes, Dorota Kwiatkowska, Barbara Berckmans, Rachel Koumproglou, Sara Maes, Tom Beeckman, Teva Vernoux, John H. Doonan, Jan Traas, Dirk Inzé, Lieven de Veylder
- article
- The Plant Journal, 2010, 64 (1), pp.26 - 37. ⟨10.1111/j.1365-313X.2010.04317.x⟩
- Accès au bibtex
- titre
- Auxin at the shoot apical meristem
- auteur
- Teva Vernoux, Fabrice Besnard, Jan Traas
- article
- Cold Spring Harbor Perspectives in Biology, 2010, 2 (4), pp.a001487. ⟨10.1101/cshperspect.a001487⟩
- Accès au texte intégral et bibtex
2009
Journal articles
- titre
- Floral stem cell termination involves the direct regulation of AGAMOUS by PERIANTHIA
- auteur
- Pradeep Das, T. Ito, F. Wellmer, Teva Vernoux, A. Dedieu, Jan Traas, Em Meyerowitz
- article
- Development (Cambridge, England), 2009, 136 (10), pp.1605-1611
- Accès au bibtex
2006
Journal articles
- titre
- Whole-genome analysis of the SHORT-ROOT developmental pathway in Arabidopsis
- auteur
- Mp Levesque, Teva Vernoux, W. Busch
- article
- PLoS Biology, 2006, 4, pp.739-752. ⟨10.1371/journal.pbio.0040143⟩
- Accès au texte intégral et bibtex
Scientific context:
From dynamic patterning to global plant architecture
Research in the SIGNAL team addresses a question central to developmental biology: how do non-linear interactions at multiple scales (molecule, cell, tissue, organism) lead to coordinated cell behaviours and to the emergence of precise forms in multi-cellular organisms?
For instance, many of our projects are connected to phyllotaxis, the geometric arrangement of leaves, branches and flowers along stems, which shows striking regularities and puzzling mathematical properties. We use both seed plants and mosses as model systems, and interdisciplinary approaches to tackle this question. To capture how developmental dynamics link genotypes to phenotypes, our approaches are deeply rooted in functional genetics and rely on quantitative phenotyping at all scales (e.g. using confocal imaging), real-time observations and computational modelling.
More specific research themes focus on:
– Hormonal signals and developmental dynamics at the shoot apical meristem
– Genetic control and robustness of inflorescence architecture
– Hormonal control and evolution of branching forms
– Multi-scale imaging solutions for the quantitative analysis of forms
Hormonal signals and developmental dynamics at the shoot apical meristem
Project leader: Teva Vernoux
Persons involved: Géraldine Brunoud (CNRS Research Engineer), Carlos Galván-Ampudia (Senior postdoc), Raquel Martin-Arevalillo (Postdoc), Estefania Pavesi (PhD Student; co-supervisor: Matias Zurbriggen, University of Düsseldorf).
The shoot apical meristem, a specialized tissue containing a stem cell niche, produces new lateral organs throughout the life of the plant. Here, we investigate how spatio-temporal distribution of hormonal signals and hormone signalling activity contribute to reiterative patterning at the shoot apical meristem.
To do so, we follow a number of complementary lines of research aiming to:
– Obtain a quantitative understanding of how the spatio-temporal distribution of auxin is controlled;
– Analyze the gene network controlling the response to auxin in space and time;
– Understand how symplasmic connections contribute to hormone distribution and patterning;
– Understand how hormones act in controlling growth at the shoot apical meristem and how this contributes to the dynamics of patterning;
– Understand the molecular mechanisms allowing auxin to act in cell fate determination;
– Decipher the molecular basis of auxin-cytokinin interactions during organ patterning at the shoot apical meristem.
We use approaches ranging from quantitative imaging, genomics, genetics to synthetic biology and computational modelling.
Main collaborators: Patrick Achard (IPMB Strasbourg), Malcolm Bennett (University of Nottingham), Anthony Bishopp (University of Nottingham), Siobhan Brady (UC Davis), Renaud Dumas (LPCV Grenoble), Christophe Godin (RDP), Jan Lohman (University of Heidelberg), François Parcy (LPCV Grenoble), François Roudier (RDP), Lyuba Ryabova (IPMB Strasbourg), Dolf Weijers (Wagenigen University), Matias Zurbriggen (University of Düsseldorf)
Genetic control and robustness of inflorescence architecture
Project leaders: Fabrice Besnard and Teva Vernoux
Persons involved: Sana Dieudonné (Ph.D Student), Stéphanie Lainé (INRA Research technician)
Here, we aim to identify key genetic mechanisms controlling plant architecture without prior assumptions. First, we are searching for plants from varied genetic backgrounds with altered shoot architecture traits indicating either a perturbation at the shoot apical meristem and/or a change in the robustness of these traits (i.e. where the variance of the trait is modified). Second, we are aiming to identify the genetic basis explaining the altered phenotypes. We expect to discover novel genes or to shed new light on how known genes act in the dynamics of plant developmental systems. When possible, we work with natural genetic variations that allow us to question how generic are the mechanisms found in laboratory lines and how phenotypic changes occur in natural populations and during evolution.
Ongoing projects are:
– Forward genetics of Arabidopsis thaliana mutants affected in organogenesis and phyllotaxis (S. Laine & F. Besnard / past member: A. Chaumeret)
We are currently investigating a few uncharacterized mutants isolated from Versailles stock center, affected in organogenesis and phyllotaxis. These mutants are in a different genetic background than the widely used Columbia‑0 accession.
– Natural variation of phyllotaxis robustness (F. Besnard)
Despite its regular nature, we showed that inflorescence phyllotaxis shows substantial variations in different genetic backgrounds. Studying those variations can reveal biological watermarks of phyllotaxis and indicate how cell behaviours are coordinated in space and time to generate phyllotactic patterns. We are currently screening different natural accessions to characterize the perturbation levels of their phyllotaxis.
– Coordination of organ identities during rapid phase transition (S. Dieudonné)
Flowering plants switch rapidly from vegetative to floral states when they start producing flowers. In Brassicaceae, including the model plant Arabidopsis thaliana, shoots stop producing basic units comprising a leaf and a branch to make only flowers. No intermediate forms are produced. Strong evidence indicates that the leaf (also called ’bract’) is suppressed when the flower arises, through yet unclear mechanisms that evolved in Brassicaceae. We identified a genetic background in Arabidopsis in which some bracts are associated with flowers at the floral transition. We are currently characterizing the genetic variations that disturb the robust coordination between bracts and flowers upon the floral transition.
Hormonal control and evolution of branching forms
Project leader: Yoan Coudert
Persons involved: Elsa Véron (PhD student), Stéphanie Laine (INRA Research technician), Jeanne Abitbol-Spangaro (PhD student).
A key aim in biology is to understand which developmental and genetic changes contributed to the evolution of form through time. In plants, the varied branching patterns emerging from the coordinated activity of meristems at the shoot tips is a key determinant of shape diversity. Hormonal cues have been shown to play a major role in branching control in distinct plant lineages. Here, we aim to understand (1) how the interplay between hormonal cues regulates branch patterning and (2) how this interplay has been remodelled in evolution to generate architectural diversity in plants. We use mosses as model organisms.
Ongoing projects are:
– Evolution of branching control and meristem function in plants
Branch patterning in the shoot is coordinated at the whole plant level by three hormones: auxin, cytokinin and strigolactone. These molecules existed before the divergence between mosses and vascular plants and were independently recruited in both plant lineages to control leafy shoot branching. In vascular plants, including Arabidopsis thaliana, long-range auxin transport is mediated by PIN proteins and is a key regulator of branching. In the moss Physcomitrium patens, pharmacological inhibitor and mutant analysis experiments have shown that homologues of PIN genes have only a minor role in shoot branching. Instead, apolar and diffusive auxin transport has been proposed as a novel regulator of branching in moss and could be mediated by callose-regulated plasmodesmal gating. Our goal is to understand how hormonal cues coordinate branching in the moss Physcomitrium patens .
– Polarity control and shoot development from a single apical cell
Phyllotaxis, the geometry of leaf arrangement around stems, determines plant architecture. Molecular interactions coordinating the formation of phyllotactic patterns have mainly been studied in multicellular shoot apical meristems of flowering plants. Phyllotaxis evolved independently in the major land plant lineages. In mosses, it arises from a single apical cell, raising the question of how the polarity and asymmetric divisions of a single-celled meristem create phyllotactic patterns and whether associated genetic processes are shared across lineages. We use the model moss, Physcomitrium patens, to investigate this fundamental biological problem and identify the mechanisms governing shoot apical cell activity.
Multiscale imaging solutions for the quantitative analysis of forms
Project leaders: Fabrice Besnard, Yoan Coudert, Teva Vernoux
Persons involved: Géraldine Brunoud (CNRS Research Engineer), Julie Charlaix (Engineer), Jonathan Legrand (CNRS Research Engineer), Carlos Galván-Ampudia (Senior postdoc), Bihai Shi (Postdoc)
A limiting factor for understanding the dynamics of shape emergence is the capacity to quantify developmental parameters in time and space at different scales. In order to capture these developmental parameters, the SIGNAL team has been and continue developing:
– Biosensors for hormones;
– Open-source robotic solution to automate the phenotyping of aerial parts of plants (and notably Arabidopsis) with high precision (and reasonable through-put);
– Software solutions for quantitative image analysis.
Main collaborators: Patrick Achard (IPMB Strasbourg), Christophe Godin (RDP), Peter Hannappe (Sony CSL Paris), Jonathan Michin (IAAC Barcelona), Verena Hafner (HU Berlin), Matias Zurbriggen (University of Düsseldorf)
Key publications:
– Coudert Y, Bell NE, Edelin C, Harrison CJ. Multiple innovations underpinned branching form diversification in mosses. New Phytologist, 10.1111/nph.14553 (2017)
– Refahi Y, Brunoud G, Farcot E, Jean-Marie A, Pulkkinen M, Vernoux T*, Godin C * (2016). A stochastic multicellular model identifies biological watermarks from disorders in self-organized patterns of phyllotaxis. eLife 5 :e14093
– Larrieu A, Champion A, Legrand J, Lavenus J, Mast D, Brunoud G, Oh J, Guyomarc’h S, Pizot M, Farmer EE, Turnbull C, Vernoux T*, Bennett M* & Laplaze L* (2015) A novel fluorescent hormone biosensor reveals the dynamics of jasmonate signaling in plants. Nature Communications 6:6043
– Coudert Y, Palubicki W, Ljung K, Novak O, Leyser O, Harrison CJ. Three ancient hormonal cues coordinate shoot branching in the moss Physcomitrella. eLife, 10.7554/eLife.06808 (2015)
– Besnard F, Refahi Y, Morin V, Marteaux B, Brunoud G., Chambrier P, Rozier F, Mirabet V, Legrand J, Lainé S, Thévenon E, Farcot E, Cellier C, Das P, Bishopp A, Dumas R, Parcy F, Helariutta Y, Boudaoud A, Godin C, Traas J, Guédon, Y, Vernoux T* (2014). Cytokinin signalling inhibitory fields provide robustness to phyllotaxis. Nature 505, 417–421
– Brunoud G, Wells DM, Oliva M, Larrieu A, Mirabet V, Burrow AH, Beeckman T, Kepinski S, Traas J, Bennett MJ, Vernoux T* (2012) A novel sensor to map auxin response and distribution at high spatio-temporal resolution. Nature 482: 103-106