{"id":700,"date":"2014-02-24T16:40:35","date_gmt":"2014-02-24T15:40:35","guid":{"rendered":"http:\/\/www.ens-lyon.fr\/crmn\/pnmr\/?page_id=700"},"modified":"2014-08-14T10:54:09","modified_gmt":"2014-08-14T09:54:09","slug":"eventstraining-course-leiden-2014","status":"publish","type":"page","link":"https:\/\/www.ens-lyon.fr\/crmn\/pnmr\/events\/eventstraining-course-leiden-2014\/","title":{"rendered":"Applied Training Course – LEIDEN 2014"},"content":{"rendered":"

Paramagnetic tagging for drug research<\/span><\/h1>\n

18th-22nd August 2014
\nLeiden, Netherlands<\/span><\/h2>\n

Registration deadline :<\/span> Thursday 26th June 2014<\/span><\/h3>\n
\"Leiden

Leiden Academy Building<\/p><\/div>\n

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Content:<\/span><\/h2>\n

Lanthanide tags are becoming popular in protein NMR to obtain structural information on protein-ligand and protein-protein complexes. The double-armed CLaNP probes provide excellent paramagnetic properties.
\nThis course will enable students to get hands-on experience on tagging a protein with a lanthanide tag, acquiring NMR spectra and analyzing the paramagnetic effects, with a particular focus on the application to protein-ligand complexes in relation to drug discovery.<\/p>\n

Location<\/strong><\/span><\/h2>\n

This Applied Training Course will take place at the Gorlaeus laboratories<\/a>, Einsteinweg 55, 2333 CC Leiden, The Netherlands.<\/p>\n

It is organised by Prof. Marcellus Ubbink of LEIDEN’s Institute of Chemistry, and Dr. Gregg Siegal from ZoBio, our Associate Partner.<\/p>\n

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Program <\/span><\/h2>\n

12:30 \u2013 13:30Lunch lecture on NMR to study protein-ligand interactions<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Monday 18th August<\/span><\/strong><\/td>\n<\/tr>\n
Arrival<\/td>\n<\/tr>\n
16:00 – 18:00<\/td>\nIntroduction to paramagnetic tagging (lectures on theory and practice)<\/td>\n<\/tr>\n
Evening<\/td>\nWelcome diner in town<\/td>\n<\/tr>\n
Tuesday 19th August<\/span><\/strong><\/td>\n<\/tr>\n
9:00 \u2013 19:00<\/td>\nPreparing protein, tagging, purification in the lab<\/td>\n<\/tr>\n
Wednesday 20th August<\/span><\/strong><\/td>\n<\/tr>\n
9:00 \u2013 19:00<\/td>\nNMR experiments and data processing<\/td>\n<\/tr>\n
Thursday 21st August<\/span><\/strong><\/td>\n<\/tr>\n
9:00 \u2013 12:30<\/td>\nAnalyse PCS and calculate magnetic susceptibility tensors<\/td>\n<\/tr>\n
13:30 \u2013 19:00<\/td>\nAnalysis and docking of ligands to a protein using PCS<\/td>\n<\/tr>\n
19:30<\/td>\nGoodbye dinner in town<\/td>\n<\/tr>\n
Friday 22nd August<\/span><\/strong><\/td>\nDeparture<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Accomodation and fee <\/span><\/h2>\n

No fee is requested from ERs and ESRs of the pNMR partner groups.
\nExternal participants fee is 300 euros. It includes all consumables, instruction, NMR costs, tea\/coffee and the two dinners.
\nPayment will be via invoice to the Leiden University.<\/p>\n

All students need to cover their expenses for accommodation and other meals.<\/p>\n

Hotels rooms will be available at about 60 euros per night on the basis of shared rooms.<\/p>\n

The number of participants is limited to ten. Participation of external students will be on a first come, first served basis.<\/p>\n

The Deadline for registration is June 26, 2014.<\/strong><\/p>\n

If you would like to participate to this course, please contact Prof. Marcellus Ubbink at m.ubbink@chem.leidenuniv.nl.<\/a><\/strong><\/span><\/p>\n

\"Leiden

Leiden Canal City Centre<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

Paramagnetic tagging for drug research 18th-22nd August 2014 Leiden, Netherlands Registration deadline : Thursday 26th June 2014 Content: Lanthanide tags are becoming popular in protein NMR to obtain structural information Continue Reading \u2192<\/a><\/p>\n","protected":false},"author":4,"featured_media":0,"parent":18,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":"","_members_access_role":[],"_members_access_error":""},"class_list":["post-700","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ens-lyon.fr\/crmn\/pnmr\/wp-json\/wp\/v2\/pages\/700","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ens-lyon.fr\/crmn\/pnmr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ens-lyon.fr\/crmn\/pnmr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ens-lyon.fr\/crmn\/pnmr\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ens-lyon.fr\/crmn\/pnmr\/wp-json\/wp\/v2\/comments?post=700"}],"version-history":[{"count":15,"href":"https:\/\/www.ens-lyon.fr\/crmn\/pnmr\/wp-json\/wp\/v2\/pages\/700\/revisions"}],"predecessor-version":[{"id":1231,"href":"https:\/\/www.ens-lyon.fr\/crmn\/pnmr\/wp-json\/wp\/v2\/pages\/700\/revisions\/1231"}],"up":[{"embeddable":true,"href":"https:\/\/www.ens-lyon.fr\/crmn\/pnmr\/wp-json\/wp\/v2\/pages\/18"}],"wp:attachment":[{"href":"https:\/\/www.ens-lyon.fr\/crmn\/pnmr\/wp-json\/wp\/v2\/media?parent=700"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}