Support teams
- [Bioinformatics Hub]
François ROUDIER
francois.roudier
(33) 4 72 72 86 04
PU ENS
Publications
Annick DUBOIS
annick.dubois
(33) 4 72 72 14 76
CR1 INRA
Publications
Aurélie VIALETTE
aurelie.vialette
(33) 4 72 72 14 79
PRAG ENS
Publications
Virginie BATTU
virginie.battu
(33) 4 72 72 86 07
AI UCBL
Publications
Daniel BOUYER
daniel.bouyer
(33) 4 72 72 86 11
CRN CNRS
Publications
Laëtitia De Faria
laetitia.de_faria
Doctorante
Nathalie MATHY-FRANCHET
nathalie.mathy-franchet
(33) 4 72 72 86 11
AI CNRS
Valentin_Bernard
valentin.bernard
Doctorant
2025
Journal articles
- titre
- Polycomb Repressive Complex 2 facilitates the transition from heterotrophy to photoautotrophy during seedling emergence
- auteur
- Naseem Samo, María Guadalupe Trejo-Arellano, Lenka Gahurová, Alexander Erban, Alina Ebert, Quentin Rivière, Jiří Kubásek, Fatemeh Aflaki, Helena Hönig Mondeková, Armin Schlereth, Annick Dubois, Mingxi Zhou, Ondřej Novák, Jiří Šantrůček, Daniel Bouyer, Francois Roudier, Joachim Kopka, Iva Mozgová
- article
- The Plant cell, 2025, ⟨10.1093/plcell/koaf148⟩
- Accès au bibtex
-
- titre
- Synthetic deconvolution of an auxin-dependent transcriptional code
- auteur
- Raquel Martin-Arevalillo, Bruno Guillotin, Jonas Schön, Alice Hugues, Marie-France Gerentes, Jeremy Lucas, Emmanuel Thevenon, Graeme Vissers, Mohammed Mohammed Ateequr, Carlos Galvan-Ampudia, Guillaume Cerutti, Jonathan Legrand, Coralie Cancé, Annick Dubois, François Parcy, Kenneth D. Birnbaum, Matias D Zurbriggen, Renaud Dumas, François Roudier, Teva Vernoux
- article
- Cell, 2025, 188 (11), ⟨10.1016/j.cell.2025.03.028⟩
- Accès au texte intégral et bibtex
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2024
Journal articles
- titre
- MIR164B ensures robust Arabidopsis leaf development by compensating for compromised POLYCOMB REPRESSIVE COMPLEX2 function
- auteur
- Aude Maugarny, Aurélie Vialette, Bernard Adroher, Anne-Sophie Sarthou, Nathalie Mathy-Franchet, Marianne Azzopardi, Antoine Nicolas, François Roudier, Patrick Laufs
- article
- The Plant cell, 2024, ⟨10.1093/plcell/koae260⟩
- Accès au texte intégral et bibtex
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Preprints, Working Papers, ...
- titre
- PRC2 facilitates the transition from heterotrophy to photoautotrophy during seedling emergence
- auteur
- Naseem Samo, María Guadalupe Trejo-Arellano, Lenka Gahurová, Alexander Erban, Alina Ebert, Quentin Rivière, Jiří Kubásek, Fatemeh Aflaki, Helena Hönig Mondeková, Armin Schlereth, Annick Dubois, Mingxi Zhou, Ondřej Novák, Jiří Šantrůček, Daniel Bouyer, Franҫois Roudier, Joachim Kopka, Iva Mozgová
- article
- 2024
- Accès au texte intégral et bibtex
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2023
Journal articles
- titre
- The Arabidopsis transcription factor NLP2 regulates early nitrate responses and integrates nitrate assimilation with energy and carbon skeleton supply
- auteur
- Mickaël Durand, Virginie Brehaut, Gilles Clement, Zsolt Kelemen, Julien Macé, Regina Feil, Garry Duville, Alexandra Launay-Avon, Christine Paysant-Le Roux, John Lunn, François Roudier, Anne Krapp
- article
- The Plant cell, 2023, 35 (5), pp.1429-1454. ⟨10.1093/plcell/koad025⟩
- Accès au bibtex
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Preprints, Working Papers, ...
- titre
- Compensation of compromised PRC2 regulation by a miRNA ensures robustness of Arabidopsis leaf development
- auteur
- Aude Maugarny, Aurélie Vialette, Bernard Adroher, Nathalie Mathy-Franchet, François Roudier, Patrick Laufs
- article
- 2023
- Accès au bibtex
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2021
Journal articles
- titre
- Deciphering Plant Chromatin Regulation via CRISPR/dCas9-Based Epigenome Engineering
- auteur
- Annick Dubois, François Roudier
- article
- Epigenomes, 2021, 5 (3), pp.17. ⟨10.3390/epigenomes5030017⟩
- Accès au texte intégral et bibtex
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- titre
- Editorial overview: Multifaceted dynamics and countless shades of green chromatin
- auteur
- Mary Gehring, François Roudier
- article
- Current Opinion in Plant Biology, 2021, 61, pp.102079. ⟨10.1016/j.pbi.2021.102079⟩
- Accès au bibtex
-
- titre
- A network of transcriptional repressors modulates auxin responses.
- auteur
- Jekaterina Truskina, Jingyi Han, Elina Chrysanthou, Carlos Galvan-Ampudia, Stéphanie Lainé, Geraldine Brunoud, Julien Macé, Simon Bellows, Jonathan Legrand, Anne-Maarit Bågman, Margot Smit, Ondrej Smetana, Arnaud Stigniani, Silvana Porco, Malcom J. Bennett, Ari Pekka Mähönen, Francois Parcy, Etienne Farcot, François Roudier, Siobhan M Brady, Anthony Bishopp, Teva Vernoux
- article
- Nature, 2021, 589 (7840), pp.116-119. ⟨10.1038/s41586-020-2940-2⟩
- Accès au texte intégral et bibtex
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2020
Journal articles
- titre
- Mitotic Inheritance of PRC2-Mediated Silencing: Mechanistic Insights and Developmental Perspectives
- auteur
- Alice Hugues, Chean Sern Jacobs, François Roudier
- article
- Frontiers in Plant Science, 2020, 11, ⟨10.3389/fpls.2020.00262⟩
- Accès au texte intégral et bibtex
-
- titre
- ChIP-seq and RNA-seq for complex and low-abundance tree buds reveal chromatin and expression co-dynamics during sweet cherry bud dormancy
- auteur
- Noémie Vimont, Fu Xiang Quah, David Guillaume Schöpfer, François Roudier, Elisabeth Dirlewanger, Philip A. Wigge, Bénédicte Wenden, Sandra Cortijo
- article
- Tree Genetics and Genomes, 2020, 16 (1), pp.9. ⟨10.1007/s11295-019-1395-9⟩
- Accès au texte intégral et bibtex
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2019
Journal articles
- titre
- Histone acetylation orchestrates wound-induced transcriptional activation and cellular reprogramming in Arabidopsis
- auteur
- Bart Rymen, Ayako Kawamura, Alice Lambolez, Soichi Inagaki, Arika Takebayashi, Akira Iwase, Yuki Sakamoto, Kaori Sako, David Favero, Momoko Ikeuchi, Takamasa Suzuki, Motoaki Seki, Tetsuji Kakutani, François Roudier, Keiko Sugimoto
- article
- Communications Biology, 2019, 2, ⟨10.1038/s42003-019-0646-5⟩
- Accès au texte intégral et bibtex
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- titre
- The m 6 A pathway protects the transcriptome integrity by restricting RNA chimera formation in plants
- auteur
- Dominique Pontier, Claire Picart, Moaine El Baidouri, François Roudier, Tao Xu, Sylvie Lahmy, Christel Llauro, Jacinthe Azevedo, Michèle Laudié, Aurore Attina, Christophe Hirtz, Marie-Christine Carpentier, Lisha Shen, Thierry Lagrange
- article
- Life Science Alliance, 2019, 2 (3), pp.e201900393. ⟨10.26508/lsa.201900393⟩
- Accès au texte intégral et bibtex
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Preprints, Working Papers, ...
- titre
- ChIP-seq and RNA-seq for complex and low-abundance tree buds reveal chromatin and expression co-dynamics during sweet cherry bud dormancy
- auteur
- Noémie Vimont, Fu Xiang Quah, David Guillaume-Schöpfer, François Roudier, Elisabeth Dirlewanger, Philip A. Wigge, Bénédicte Wenden, Sandra Cortijo
- article
- 2019
- Accès au texte intégral et bibtex
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2018
Book sections
- titre
- Cell Type-Specific Profiling of Chromatin Modifications and Associated Proteins
- auteur
- Ana Karina Morao, Erwann E. Caillieux, Vincent Colot, François Roudier
- article
- Plant Chromatin Dynamics, pp.111-130, 2018, ⟨10.1007/978-1-4939-7318-7_8⟩
- Accès au bibtex
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- titre
- Chromatin Immunoprecipitation Sequencing (ChIP-Seq) for Transcription Factors and Chromatin Factors in Arabidopsis thaliana Roots: From Material Collection to Data Analysis
- auteur
- Sandra S. Cortijo, Varodom Charoensawan, François Roudier, Philip A. Wigge
- article
- Root Development, pp.231-248, 2018, ⟨10.1007/978-1-4939-7747-5_18⟩
- Accès au bibtex
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2017
Journal articles
- titre
- Epigenetic memory and cell fate reprogramming in plants
- auteur
- Kenneth D. Birnbaum, François Roudier
- article
- Regeneration, 2017, 4 (1), pp.15-20. ⟨10.1002/reg2.73⟩
- Accès au texte intégral et bibtex
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2016
Journal articles
- titre
- A versatile Multisite Gateway-compatible promoter and transgenic line collection for cell type-specific functional genomics in Arabidopsis
- auteur
- Maria Mar Marquès-Bueno, Ana K. Morao, Anne Cayrel, Matthieu P. Platre, Marie Barberon, Erwann Caillieux, Vincent Colot, Yvon Jaillais, François Roudier, Grégory Vert
- article
- The Plant Journal, 2016, 85 (2), pp.320--333. ⟨10.1111/tpj.13099⟩
- Accès au texte intégral et bibtex
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About Our Team
The research carried out by the EpiCDev team aims to understand how epigenetic regulations shape developmental programs in plants, particularly at the level of cell differentiation. To understand how chromatin dynamics enable cells to respond selectively to developmental and environmental signals, we use innovative, multi-scale approaches in the flowering plant Arabidopsis thaliana and the moss Physcomitrium patens.
Our main areas of research focus on:
- The regulation of transcription by Polycomb PRC2 complexes during development
- The influence of chromatin state dynamics on transcription factor activity
- The role of DNA methylation on male fertility and reproductive success
In addition to these research activities, we are actively engaged in training and scientific outreach to raise awareness of the role of plant biology in responding to major global challenges.
Research Axis 1: Meristematic and developmental functions of PRC2
We are studying how the activity of PRC2 repressive complexes modulates gene expression during embryogenesis and rhizogenesis in Arabidopsis, as well as during the development of Physcomitrium.
Research Axis 2: Chromatin interface and transcription factors
This line of research, mainly conducted collaboratively, studies how the organization of the epigenome influences transcription factors’ access to DNA, thereby modulating responses to environmental and developmental signals.
Research Axis 3: DNA Methylation and Male Fertility
We analyze how active DNA demethylation contributes to reproductive success by regulating genes essential for pollen function and male fertility in Arabidopsis.
| Team members | . |
| François Roudier | Professor ENS (co-group leader) |
| Daniel Bouyer | Senior Researcher CNRS (co-group leader) |
| Annick Dubois | Senior Researcher INRAe |
| Nathalie Franchet-Mathy | Assistant Engineer CNRS |
| Virginie Battu | Research technician UCBL |
| Laëtitia De Faria | PhD Student (ED BMIC) |
| Valentin Bernard | PhD Student (ED BMIC) |
Alumni
PhD students - Postdocs
Chean Sern Jacobs (PhD student ED bmic)
Nicolas Dalle (PhD student ED bmic & ATER UCBL)
Alice Hugues (PhD student ED bmic)
Aurélie Vialette (ENS lecturer - postdoc)
Bioinformatics support staff
Julia Buttin (IE bioinfo CDD ENS)
Julien Macé (IE Bioinfo CDD ENS)
Jérémy Just (40%) (IR bioinfo CNRS)
Bertrand Huguenin-Bizot (IE bioinfo CDD CNRS)
Molecular and cellular biology support staff
Marie France Gérentes (IE CDD ENS)
Internship students
Allan Bernard (M2 ENS)
Mohammad Muhieddine (M2 ENS)
Tristan Conot (pre-master ENS)
Goeffrey Schivre (M1 U. Montpellier)
Alice Hugues (M2 ENS)
Marie Biharé (M1 U. Lille)
Laure Cuby (ESTBB Lyon)
Lucas Auroux (M2 U. Strasbourg)
Emma Désert (M1 UCBL1)
Colline Richard (pre-master ENS)
Marjorie Sublet (ESTBB)
Mattéo Veyre (Sup Biotech)
Aleksandra Lefevre (M1 ENS)
Françoise Monéger (DR CNRS, Retired)