CV Marie-Cécile Caillaud

Curriculum vitæ

Family name, First name : Caillaud Marie-Cécile
Researcher unique identifiers : ORCID : 0000-0002-0348-7024
Researcher ID : G-9320-2018
Date of birth : 14/10/1982
Nationality : French

URL for web site : Cell Signalling and Endocytosis

Education

2019 Habilitation à Diriger la Recherche (ENS Lyon, FR)

2005-2009 PhD in Molecular and Cellular Biology (University of Nice Sophia-Antipolis, FR) supervised by Dr Pierre ABAD (Pierre.Abad@sophia.inra.fr).

2003-2005 Master of “Biology of Adaptations and Interactions” (with distinction)

Master of “Ecology, Evolution and Genome Plasticity” (with distinction)
University of Nice Sophia-Antipolis, FR.

Current position

Since 2014 Junior group leader “Cell division and membrane lipids” at the RDP.

Previous position

2014-2016 “Chargé de Recherche, CRCN” (Permanent Researcher Position)
Laboratoire de Reproduction et Développement des Plantes, ENS Lyon

2009-2013 Postdoctoral Research Fellow with Prof. Jonathan Jones (jonathan.jones@tsl.ac.uk) at The Sainsbury Laboratory, Norwich (UK).

Fellowships, Fundings, and Awards

2005-2009 MENRT PhD Scholarship Salary
2009-2010 Long Term EMBO Fellowship (ALTF 614-2009)‏ Salary
2010-2012 Long Term Marie Curie Fellowship (FP7-PEOPLE-2009-IEF)‏ 170K₤
2012-2015 Associated Investigator of UK BBSRC Grant (BB/K009176/1) 600K₤
2016-2018 Seed Fund ENS LYON-2016 28K€
2017-2021 Junior Investigator grant (ANR-16-CE13-0021) 300K€
06/2019 Interview for ERC Starting Grant (ranked A, not funded)
2020-2022 Seed Fund ENS LYON-2019 35K€
2021-2025 Associated Investigator of PlantScape (ANR-20-CE13-0026-02) 500K€
2022-2026 Associated Investigator of DivCON (ANR-21-CE13-0016-03) 510K€

Supervision and Teaching activities

2005-2009 Teaching position at the University of Nice Sophia-Antipolis during my PhD. Level : Bachelor and Master. (64 h/year, during 4 years).

2018 Practical in imaging : “From samples to quantification” at ENS Lyon, FR Level : Master Advanced Course (36 h)

2019 Seminar : “Role of the Phosphoinositides in Plant Cell Division” at the Máster Oficial en Biotecnología Avanzada, Malaga, SP ? Level : Master Advanced Course (1 h)

PhD committee Sophie Piquerez, UEA Norwich, UK ; Alvaro Montiel Jorda, University of Toulouse, FR ; Mathilde Simon, Nathanaël Jacquier, Estefania Pavesi, ENS LYON, FR

BSc Internship Emilie Andrio, UNSA, FR ; Lucas Courgeon, ENS LYON, FR

Master Mehdi Doumane, ENS LYON, FR ; Alexis Lebecq, UNSA, FR ; Amélie Bauer, University of Lyon 1, FR ; Elsa Gascon, INSA Lyon, FR

PhD Thesis Mehdi Doumane, ENS LYON, FR ; Alexis Lebecq ENS LYON, FR

Reviewing activities

Since 2014 Reviewer PUBLONS
Since 2014 Scientific Evaluation, Labex Saclay Plant Science (FR), Croatian Science Foundation
2021 – 2023 Member of the FWO Review College (Belgium National funding committee)

Editorial activities

2014-2015 Editor for special edition in “Plant Cell Division” for MiMB, Springer
2020-2021 Editor for the second edition of Plant Cell Division for MiMB, Springer

National Responsibilities

2021 Member of the Section 23 of the CNRS (Biologie végétale intégrative)

Local Responsibilities

2015 - Health and Safety Officer
2021 - Referent CNRS for the psychosocial risk

Patents

 Favery, B., Abad P., Caillaud, M.C. (2010) US 20110030095 A1 "Method for increasing the resistance of a plant to endoparasitic nematodes".
 Favery, B., Abad P., Caillaud, M.C. (2008) Procédé pour augmenter la résistance d’une plante aux nématodes endoparasites EP1992699, Munich (GER) : European Patent Office. 41 p.

Oral communications

Invited talks :
(2022) 25th International Symposium on Plant Lipids, Grenoble, (France)
(2022) 4th Jacques Monod Conference on ‘Molecular basis for membrane remodeling and organization’ (France) May 10-15 2022
(2020) INUPRAG-BAICTMD meeting (canceled)
(2019) 12th PhD School Plant Development Retzbach (Germany)
(2018) European Plant Cytoskeletal Club 2018, Prague (CR)
(2015) International meeting of the GS of Cell Biology (Germany)
(2013) Effectome meeting, Montpellier (France).
(2013) Fungal Genomic conference, Asilomar (USA).
Selected talks : (2018) Plant Endocytosis Workshop, Wiston House, (UK)
(2012) ICAR, Vienna (Austria)
(2008) COST Action 872 ; 2nd Annual Meeting, Postojna (Slovenia).
(2007) Molecular Plant-Microbe Interactions, Sorrento (Italie).
Invited lectures : (2020) IBIP Montpellier (FR) ; Host : Alexandre Martinière
(2019) INRAe Versailles (FR) ; Host : Martine Pastuglia

Career breaks

  • 15/10/2013 to 01/10/2014 Maternity leave
  • 15/09/2016 to 15/05/2017 Maternity leave

PUBLICATIONS

  • Caillaud M. C. (in revision) "Modifying the Cytoskeleton during Plant Cell Division". Trends in Plant Science
  • Doumane, M., M.-C. Caillaud* and Y. Jaillais* (in press) “Experimental Manipulation of Phosphoinositide lipids, from cells to organisms” Trends in Cell Biology. co-corresponding author
  • Lebecq, A., A. Fangain, A. Boussaroque and M.-C. Caillaud (in press). "Dynamic Apical-Basal Enrichment of the F-Actin during Cytokinesis in Arabidopsis Cells Embedded in their Tissues." Quantitative Plant Biology. corresponding author
  • Caillaud, M. C., (2022) Methods to visualize the Actin Cytoskeleton During Plant Cell Division, Method in Molecular Biology DOI : 10.1007/978-1-0716-1744-1_1
    Caillaud, M.-C., (2022) Plant cell division : methods and protocols. Preface, (Methods in Molecular Biology)
  • Doumane, M., A. Lebecq, A. Fangain, V. Bayle, F. Rozier, M. d. M. Marquès-Bueno, R. P. Boisseau, M. L. A. Simon, L. Armengot, Y. Jaillais and M.-C. Caillaud (2021). "The Arabidopsis SAC9 Enzyme defines a cortical population of early endosomes and restricts PI(4,5)P2 to the Plasma Membrane."doi : https://doi.org/10.1101/2021.09.10.459735. co-corresponding author
  • Saile, S. C., F. M. Ackermann, S. Sunil, J. Keicher, A. Bayless, V. Bonardi, L. Wan, M. Doumane, E. Stöbbe, Y. Jaillais, M.-C. Caillaud, J. L. Dangl, M. T. Nishimura, C. Oecking and F. El Kasmi (2021). "Arabidopsis ADR1 helper NLR immune receptors localize and function at the plasma membrane in a phospholipid dependent manner." New Phytologist 232(6) : 2440-2456.
  • Noack, L., V. Bayle, L. Armengot, F. Rozier, A. Mamode-Cassim, F. Stevens, M. C. Caillaud, T. Munnik, S. Mongrand and Y. Jaillais (2021). "A nanodomain anchored-scaffolding complex is required for PI4Kα function and localization in plants." The Plant Cell
  • Doumane, M., L. Colin, A. Lebecq, A. Fangain, J. Bareille, O. Hamant, Y. Belkhadir, Y. Jaillais* and M.-C. Caillaud* (2021). "iDePP : a genetically encoded system for the inducible depletion of PI(4,5)P2 in Arabidopsis thaliana." Nature Plants, *Co-corresponding author.
  • Doumane, M. and M. C. Caillaud (2020). "Assessing Extrinsic Membrane Protein Dependency to PI4P Using a Plasma Membrane to Endosome Relocalization Transient Assay in Nicotiana benthamiana." Methods Mol Biol 2177 : 95-108. corresponding author
  • Caillaud, M.-C. (2019) Anionic Lipids : a Pipeline Connecting Key Players of Plant Cell Division. Frontiers in Plant Sciences doi:10.3389/fpls.2019.00419
  • Platre MP, Noack LC, Doumane M, Bayle V, Simon MLA, Maneta-Peyret L, Fouillen L, Stanislas T, Armengot L, Pejchar P, Caillaud MC, Potocky M, Copic A, Moreau P, Jaillais Y (2018) A Combinatorial Lipid Code Shapes the Electrostatic Landscape of Plant Endomembranes. Dev Cell 45 (4):465-480
  • Doumane, M., C. Lionnet, V. Bayle, Y. Jaillais and M. C. Caillaud (2017). "Automated Tracking of Root for Confocal Time-lapse Imaging of Cellular Processes." Bio Protoc. 2017 ;7(8). doi : 10.21769/BioProtoc.2245. corresponding author
  • Simon, M. L., M. P. Platre, M. M. Marques-Bueno, L. Armengot, T. Stanislas, V. Bayle, M. C. Caillaud* and Y. Jaillais* (2016). "A PtdIns(4)P-driven electrostatic field controls cell membrane identity and signalling in plants." Nature Plant 10.1038/nplants.2016.89. *Co-corresponding author.

The paper above was featured in Nature Plants by a news and views commentary by Jiri Friml and colleagues “Plasma membrane : Negative attraction”
Highlighted on the F1000 website
Press release by CNRS and ENS Lyon

  • Caillaud, M.-C., (2016) Plant cell division : methods and protocols. Preface, (Methods in Molecular Biology, 1370) DOI : 10.1007/978-1-4939-3142-2
  • Quentin, M., I. Baures, C. Hoefle, M. C. Caillaud, V. Allasia, F. Panabieres, P. Abad, R. Huckelhoven, H. Keller and B. Favery (2016). The Arabidopsis microtubule-associated protein MAP65-3 supports infection by filamentous biotrophic pathogens by down-regulating salicylic acid-dependent defenses. J Exp Bot 67(6) : 1731-1743.
  • Caillaud, M. C. and B. Favery (2016). "In Vivo Imaging of Microtubule Organization in Dividing Giant Cell." Methods Mol Biol 1370 : 137-144. Cited by 2
  • Caillaud, MC, Wirthmueller L, Sklenar J, Findlay K, Piquerez SJ, Jones AM, Robatzek S, Jones JD and Faulkner C (2014). The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition. PLoS Pathog 10(10) : e1004496.
  • Asai, S., G. Rallapalli, S. J. Piquerez, M. C. Caillaud, O. J. Furzer, N. Ishaque, L. Wirthmueller, G. Fabro, K. Shirasu and J. D. Jones (2014). Expression profiling during arabidopsis/downy mildew interaction reveals a highly-expressed effector that attenuates responses to salicylic acid. PLoS Pathog 10(10) : e1004443.
  • Caillaud MC, Asai S, Rallapalli G, Piquerez SJ, Fabro G, Jones JD (2013). An Arabidopsis downy mildew Effector Attenuates Salicylic Acid-Triggered Immunity (SATI) via interactions with the host Mediator complex. PLoS Biology doi:10.1371/journal.pbio.1001732
  • Caillaud MC, Wirthmueller L, Fabro G, Piquerez SJ, Asai S, Ishaque N, Jones JD (2013). Mechanisms of Nuclear Suppression of Host Immunity by Effectors from the Arabidopsis Downy Mildew Pathogen Hyaloperonospora arabidopsidis (Hpa). Cold Spring Harb Symp Quant Biol
  • Caillaud MC, Piquerez SJ, Fabro G, Steinbrenner J, Ishaque N, Beynon J, Jones JD (2012). Subcellular localisation of the Hpa RxLR effector repertoire identifies a tonoplast-associated protein HaRxL17 that confers enhanced plant susceptibility. Plant J 69 : 252-265
  • Fabro G, Steinbrenner J, Coates M, Ishaque N, Baxter L, Studholme DJ, Korner E, Allen RL, Piquerez SJ, Rougon-Cardoso A, Greenshields D, Lei R, Badel JL, Caillaud MC, Sohn KH, Van den Ackerveken G, Parker JE, Beynon J, Jones JD (2011). Multiple candidate effectors from the oomycete pathogen Hyaloperonospora arabidopsidis suppress host plant immunity. PLoS Pathog 7 : e1002348
  • Caillaud MC, Paganelli L, Lecomte P, Deslandes L, Quentin M, Pecrix Y, Le Bris M, Marfaing N, Abad P, Favery B (2009). Spindle assembly checkpoint protein dynamics reveal conserved and unsuspected roles in plant cell division. PLoS One 4 : e6757 Cited by 52
  • Caillaud MC, Dubreuil G, Quentin M, Perfus-Barbeoch L, Lecomte P, de Almeida Engler J, Abad P, Rosso MN, Favery B (2008). Root-knot nematodes manipulate plant cell functions during a compatible interaction. J Plant Physiol 165 : 104-113 Cited by 202
  • Caillaud MC, Abad P, Favery B (2008). Cytoskeleton reorganization, a key process in root-knot nematode-induced giant cell ontogenesis. Plant Signal Behav 3 : 816-818,
  • Abad P, Gouzy J, Aury JM, Castagnone-Sereno P, Danchin EG, Deleury E, Perfus-Barbeoch L, Anthouard V, Artiguenave F, Blok VC, Caillaud MC, Coutinho plasma membrane, Dasilva C, De Luca F, Deau F, Esquibet M, Flutre T, Goldstone JV, et al., (2008). Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita. Nature Biotech 26 : 909-915, Cited by 774
    The paper above was featured in Nature Biotechnology by a news and views commentary by James P McCarter “Nematology : terra incognita no more”
    Highlighted on the F1000 website
    Press release by INRA
  • Caillaud MC, Lecomte P, Jammes F, Quentin M, Pagnotta S, Andrio E, de Almeida Engler J, Marfaing N, Gounon P, Abad P, Favery B (2008). MAP65-3 microtubule-associated protein is essential for nematode-induced giant cell ontogenesis in Arabidopsis. Plant Cell 20 : 423-437