08:30 am - 09:00 am |
Welcome |
09:00 am - 09:40 am |
Chair: Daniel KAHN, Lyon, France Ines THIELE, Esch-sur-Alzette, Luxembourg Personalized whole-body models integrate metabolism, physiology, and the gut microbiome |
09:40 am - 10:20 am |
Chair: Daniel KAHN, Lyon, France Uwe SAUER, Zurich, Switzerland Metabolic coordination through metabolite-protein interactions |
10:20 am - 10:50 am |
Coffee break |
10:50 am - 12:30 pm |
Three parallel sessions
Methodological developments for Systems Biology B
Chair: Mustafa KHAMMASH, Basel, Switzerland
Satya SAMAL, Aachen, Germany 10:50 am - 11:10 am Sensitive parameters and tipping points of biochemical networks with potential applications in precision medicine
Anne POUPON, Nouzilly, France 11:10 am - 11:30 am Parameter estimation in dynamical models for systems biology – the delicate balance between identifiability and predictivity
Ozgur AKMAN, Exeter, United Kingdom 11:30 am - 11:50 am The parameter explosion problem: extending the scope of GRN modelling by combining reduced models with evolutionary computation
Martial GUILLAUD, Vancouver, Canada 11:50 am - 12:10 pm Hyperspectral cell sociology analysis of histological specimens
Serge PELET, Lausanne, Switzerland 12:10 pm - 12:30 pm Dynamic single cell analysis of a cell fate decision system
Systems Medicine B
Chair: Jacqueline MARVEL, Lyon, France
Teresa LEHNERT, Jena, Germany 10:50 am - 11:10 am Characterization of different sepsis phases by virtual infection modeling of the innate immune response in human whole blood
Anna MEDYUKHINA, Jena, Germany 11:10 am - 11:30 am Automated image analysis of mast cell - dendritic cell interactions reveals weapon transfer in immune system
Chloe AUDEBERT, Villeurbanne, France 11:30 am - 11:50 am Non-linear mixed effects models to study inter-individual variability in CD8 T cell immune responses in mice.
Chen-Hsiang YEANG, Taipei, Taiwan 11:50 am - 12:10 pm Modelling bistable tumour population dynamics to design effective treatment strategies
Marcel SCHILLING, Heidelberg, Germany 12:10 pm - 12:30 pm The complex life of Smad isoforms determines gene expression in hepatocellular carcinoma
Modelling Networks and Circuits B
Chair: Ina KOCH, Frankfurt, Germany
Jonas BÉAL, Paris, France 10:50 am - 11:10 am Instantiation of patient-specific logical models with multi-omics data allows clinical stratification of patients
Oleksii RUKHLENKO, Dublin, Ireland 11:10 am - 11:30 am Structure-based kinetic modelling reveals kinase inhibitor combinations to overcome oncogenic RAS signalling
Yaroslav NIKOLAEV, Zurich, Switzerland 11:30 am - 11:50 am Systems NMR: simultaneous quantitative monitoring of RNA, protein, and metabolite dynamics for biomolecular network analysis
Daniel JOST, La Tronche, France 11:50 am - 12:10 pm Assigning function to natural allelic variation via dynamic modeling of gene network induction
Ulysse HERBACH, Lyon, France 12:10 pm - 12:30 pm Inferring gene regulatory networks using single-cell data: from mechanistic modelling to statistics
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12:30 pm - 02:00 pm |
Lunch |
02:00 pm - 03:30 pm |
Poster session |
03:30 pm - 04:00 pm |
Coffee break |
04:00 pm - 05:40 pm |
Three parallel sessions
Methodological developments for Systems Biology C
Chair: Anne POUPON, Nouzilly, France
Laurent GUYON, Grenoble, France 04:00 pm - 04:20 pm miRNA selection using miRNA network a priori showed improved reliability and identify functionally related miRNAs
Andras GYORGY, Abu Dhabi, United Arab Emirates 04:20 pm - 04:40 pm Optimal part characterization with shared cellular resources
Arthur GOLDBERG, New York, United States 04:40 pm - 05:00 pm A multialgorithmic simulator for whole-cell biochemical models
Silas Boye NISSEN, Copenhagen, Danmark 05:00 pm - 05:20 pm Four simple rules that are sufficient to generate the mammalian blastocyst
Jörn STARRUSS, Dresden, Germany 05:20 pm - 05:40 pm Morpheus: a user-friendly and extensible simulation framework for declarative modelling in multiscale and multicellular systems biology
Systems Medicine C
Chair: Maria Manuela NOGUEIRA, Lyon, France
Fortunato BIANCONI, Perugia, Italy 04:00 pm - 04:20 pm Machine learning pipeline for pathways analysis with reverse phase microarray data of non-small cell lung cancer cell lines and different drugs
Michiel ADRIAENS, Maastricht, Netherlands 04:20 pm - 04:40 pm Putting the squeeze on RNA-seq data: mapping individualized genetic and epigenetic regulation in complex diseases
Avijit PODDER, New Delhi, India 04:40 pm - 05:00 pm Therapeutic understanding of human dopaminergic system in neurological diseases - a systems biology approach
Pedro MENDES, Farmington, United States 05:00 pm - 05:20 pm Transforming physiological models from mice to humans - the case of iron homeostasis.
Dominik LUTTER, Neuherberg, Germany 05:20 pm - 05:40 pm A circadian metabolomics atlas of the body under chronic nutrient stress
Modelling Networks and Circuits C
Chair: Ralf STEUER, Berlin, Germany
Niklas KORSBO, Cambridge, United Kingdom 04:20 pm - 04:40 pm Precise adaptation in stem cell control
Martin ZAUSER, Heidelberg, Germany 04:40 pm - 05:00 pm Automated image analysis and modeling of calcium waves in plant roots
Jian-Geng CHIOU, Durham, United States 05:00 pm - 05:20 pm Principles that govern competition or co-existence in Rho-GTPase driven polarization in the budding yeast
Atsushi MOCHIZUKI, Kyoto, Japan 05:20 pm - 05:40 pm Controlling cell fate specification system based on network structure
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05:50 pm - 06:30 pm |
Chair: Annamaria CARUSI, Sheffield, UK Barbara PRAINSACK, Vienna, Austria Is precision medicine “open”? |