Hormonal Signalling and Development

Personnel du RDP

Teva VERNOUX

teva.vernoux
(33) 4 72 72 86 01
DR CNRS
Publications

Fabrice BESNARD

fabrice.besnard
(33) 4 72 72 89 82
CR INRAe

Yoan COUDERT

yoan.coudert
(33) 4 72 72 89 82
CR CNRS
Publications

Géraldine BRUNOUD

geraldine.brunoud
(33) 4 72 72 86 04
IR CNRS
Publications

Jonathan LEGRAND

jonathan.legrand
(33)4 72 72 86 04
IR CNRS
Publications

Stéphanie HALLET

stephanie.hallet
(33) 4 72 72 86 03
TR INRAe

Aurèle MACE

aurele.mace
(33) 4 72 72 XX XX
CDD IR - ROMI H2020

Carlos GALVAN-AMPUDIA

carlos.galvan-ampudia
(33) 4 72 72 86 14
Postdoc CNRS

Elsa VERON

elsa.veron
(33) 4 72 72 XX XX
Thèse

Estefania Pavesi

pavesi AT uni-duesseldorf.de

Florence Agbazahou

florence.agbazahou
(33) 4 72 72 XX XX
AI - ANR Hydrofields

Julie CHARLAIX

julie.charlaix
(33) 4 72 72 XX XX
CDD IE INRA

Justine BOITEL

justine.boitel
(33) 4 72 72 XX XX
CDD IE

Raquel MARTIN

raquel.martin
(33) 4 72 72 86 06
Post-Doc

Sana DIEUDONNE

sana.dieudonne
Thesis ENS

Wenqian CHEN

wenqian.chen
(33) 4 72 72 XX XX
CDD IE



Publications HAL du labo/EPI 1001887;772

2021

Journal articles

titre
A network of transcriptional repressors modulates auxin responses.
auteur
Jekaterina Truskina, Jingyi Han, Elina Chrysanthou, Carlos Galvan-Ampudia, Stéphanie Lainé, Geraldine Brunoud, Julien Macé, Simon Bellows, Jonathan Legrand, Anne-Maarit Bågman, Margot Smit, Ondrej Smetana, Arnaud Stigniani, Silvana Porco, Malcom J. Bennett, Ari Pekka Mähönen, Francois Parcy, Etienne Farcot, François Roudier, Siobhan M Brady, Anthony Bishopp, Teva Vernoux
article
Nature, Nature Publishing Group, 2021, 589 (7840), pp.116-119. ⟨10.1038/s41586-020-2940-2⟩
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https://hal.archives-ouvertes.fr/hal-03021204/file/Truskina_%20main_text_all-rev6_CorrLegendFig3_withallFig.pdf BibTex
titre
Phyllotaxis from a Single Apical Cell
auteur
Elsa Véron, Teva Vernoux, Yoan Coudert
article
Trends in Plant Science, Elsevier, In press, 26 (2), pp.124-131. ⟨10.1016/j.tplants.2020.09.014⟩
Accès au texte intégral et bibtex
https://hal.archives-ouvertes.fr/hal-03011975/file/Veron%20et%20al%20TIPS%202020_HAL%20version.pdf BibTex
titre
Developmental roles of Auxin Binding Protein 1 in Arabidopsis thaliana
auteur
Zuzana Gelová, Michelle Gallei, Markéta Pernisová, Geraldine Brunoud, Xixi Zhang, Matouš Glanc, Lanxin Li, Jaroslav Michalko, Zlata Pavlovičová, Inge Verstraeten, Huibin Han, Jakub Hajný, Robert Hauschild, Milada Čovanová, Marta Zwiewka, Lukas Hoermayer, Matyáš Fendrych, Tongda Xu, Teva Vernoux, Jiří Friml
article
Plant Science, Elsevier, 2021, 303, pp.110750. ⟨10.1016/j.plantsci.2020.110750⟩
Accès au texte intégral et bibtex
https://hal.archives-ouvertes.fr/hal-03030481/file/1-s2.0-S0168945220303563-main.pdf BibTex

2020

Journal articles

titre
Temporal integration of auxin information for the regulation of patterning
auteur
Carlos Galvan-Ampudia, Guillaume Cerutti, Jonathan Legrand, Geraldine Brunoud, Raquel Martin Arevalillo, Romain Azaïs, Vincent Bayle, Steven Moussu, Christian Wenzl, Yvon Jaillais, Jan U Lohmann, Christophe Godin, Teva Vernoux
article
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/eLife.55832⟩
Accès au texte intégral et bibtex
https://hal.archives-ouvertes.fr/hal-02368529/file/elife-55832-v1%20%283%29.pdf BibTex
titre
Methods to Visualize Auxin and Cytokinin Signaling Activity in the Shoot Apical Meristem.
auteur
Geraldine Brunoud, Carlos Galvan-Ampudia, Teva Vernoux
article
Methods in Molecular Biology, Humana Press/Springer Imprint, 2020, 2094, pp.79-89. ⟨10.1007/978-1-0716-0183-9_9⟩
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https://hal.archives-ouvertes.fr/hal-03019935/file/Brunoud_main.pdf BibTex
titre
Low Blue Light Enhances Phototropism by Releasing Cryptochrome1-Mediated Inhibition of PIF4 Expression.
auteur
Alessandra Boccaccini, Martina Legris, Johanna Krahmer, Laure Allenbach-Petrolati, Anupama Goyal, Carlos Galvan-Ampudia, Teva Vernoux, Elizabeth Karayekov, Jorge Casal, Christian Fankhauser
article
Plant Physiology, American Society of Plant Biologists, 2020, 183 (4), pp.1780-1793. ⟨10.1104/pp.20.00243⟩
Accès au texte intégral et bibtex
https://hal.archives-ouvertes.fr/hal-03020288/file/1780.full.pdf BibTex

2019

Journal articles

titre
WUSCHEL acts as an auxin response rheostat to maintain apical stem cells in Arabidopsis
auteur
Yanfei Ma, Andrej Miotk, Olga Ermakova, Christian Wenzl, Anna Medzihradszky, Christophe Gaillochet, Joachim Forner, Gözde Utan, Klaus Brackmann, Carlos Galvan-Ampudia, Teva Vernoux, Thomas Greb, Jan Lohmann
article
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-13074-9⟩
Accès au texte intégral et bibtex
https://hal.archives-ouvertes.fr/hal-02386567/file/2019_Ma_Nat_Commun_1.pdf BibTex
titre
Design Principles of Branching Morphogenesis in Filamentous Organisms
auteur
Yoan Coudert, Steven Harris, Bénédicte Charrier
article
Current Biology - CB, Elsevier, 2019, 29 (21), pp.R1149 - R1162. ⟨10.1016/j.cub.2019.09.021⟩
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https://hal.archives-ouvertes.fr/hal-02999235/file/2019_CB_Coudert2.pdf BibTex
titre
Evolution of the Auxin Response Factors from charophyte ancestors
auteur
Raquel Martin-Arevalillo, Emmanuel Thevenon, Fanny Jégu, Thomas Vinos-Poyo, Teva Vernoux, François Parcy, Renaud Dumas
article
PLoS Genetics, Public Library of Science, 2019, 15 (9), pp.e1008400. ⟨10.1371/journal.pgen.1008400⟩
Accès au texte intégral et bibtex
https://hal.archives-ouvertes.fr/hal-02329218/file/2019_Martin_Plos_Gen_1.pdf BibTex
titre
The RIN ‐regulated Small Auxin‐Up RNA SAUR 69 is involved in the unripe‐to‐ripe phase transition of tomato fruit via enhancement of the sensitivity to ethylene
auteur
Jun‐hye Shin, Isabelle Mila, Mingchun Liu, Maria Aurineide Rodrigues, Teva Vernoux, Julien Pirrello, Mondher Bouzayen
article
New Phytologist, Wiley, 2019, 222 (2), pp.820-836. ⟨10.1111/nph.15618⟩
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titre
Dissecting the pathways coordinating patterning and growth by plant boundary domains
auteur
Aude Maugarny-Calès, Millan Cortizo, Bernard Adroher, Néro Borrega, Beatriz Gonçalves, Geraldine Brunoud, Teva Vernoux, Nicolas Arnaud, Patrick Laufs
article
PLoS Genetics, Public Library of Science, 2019, 15 (1), pp.e1007913. ⟨10.1371/journal.pgen.1007913⟩
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https://hal.archives-ouvertes.fr/hal-02386592/file/2018_Maugarny-Cal%C3%A8s_Plos%20Genetics_1.pdf BibTex
titre
Reconstructing trait evolution in plant evo–devo studies
auteur
Pierre-Marc Delaux, Alexander Hetherington, Yoan Coudert, Charles Delwiche, Christophe Dunand, Sven Gould, Paul Kenrick, Fay-Wei Li, Herve Philippe, Stefan Rensing, Mélanie Rich, Christine Strullu-Derrien, Jan de Vries
article
Current Biology - CB, Elsevier, 2019, 29 (21), pp.R1110-R1118. ⟨10.1016/j.cub.2019.09.044⟩
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https://hal.archives-ouvertes.fr/hal-02355085/file/Reconstructing%20trait%20evolution%20-%20A%20guideline%20for%20plant%20evo-devo%20studies%20%28and%20beyond%29_revised.pdf BibTex
titre
Capturing Auxin Response Factors Syntax Using DNA Binding Models
auteur
Arnaud Stigliani, Raquel Martin-Arevalillo, Jérémy Lucas, Adrien Bessy, Thomas Vinos-Poyo, Victoria Mironova, Teva Vernoux, Renaud Dumas, François Parcy
article
Molecular Plant, Cell Press/Oxford UP, 2019, 12 (6), pp.822-832. ⟨10.1016/j.molp.2018.09.010⟩
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https://hal.archives-ouvertes.fr/hal-02088272/file/Stigliani_total.pdf BibTex
titre
Shining light on plant hormones with genetically encoded biosensors
auteur
Raquel Martin Arevalillo, Teva Vernoux
article
Biological Chemistry, De Gruyter, 2019, 400 (4), pp.477-486. ⟨10.1515/hsz-2018-0310⟩
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Book sections

titre
Patterning at the shoot apical meristem and phyllotaxis
auteur
Teva Vernoux, Shi Bihai
article
Current Topics in Developmental Biology, 131, Elsevier Academic Press Inc., 11 p., 2019, Current Topics in Developmental Biology, 978-0-12-809804-2. ⟨10.1016/bs.ctdb.2018.10.003⟩
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2018

Journal articles

titre
Root branching toward water involves posttranslational modification of transcription factor ARF7
auteur
Beatriz Orosa-Puente, Nicola Leftley, Daniel von Wangenheim, Jason Banda, Anjil Srivastava, Kristine Hill, Jekaterina Truskina, Rahul Bhosale, Emily Morris, Moumita Srivastava, Britta Kümpers, Tatsuaki Goh, Hidehiro Fukaki, Joop Vermeer, Teva Vernoux, José Dinneny, Andrew French, Anthony Bishopp, Ari Sadanandom, Malcolm Bennett
article
Science, American Association for the Advancement of Science, 2018, 362 (6421), pp.1407-1410. ⟨10.1126/science.aau3956⟩
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titre
A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate
auteur
Rahul Bhosale, Jitender Giri, Bipin Pandey, Ricardo Giehl, Anja Hartmann, Richard Traini, Jekaterina Truskina, Nicola Leftley, Meredith Hanlon, Kamal Swarup, Afaf Rashed, Ute Voß, Jose Alonso, Anna Stepanova, Jeonga Yun, Karin Ljung, Kathleen Brown, Jonathan Lynch, Liam Dolan, Teva Vernoux, Anthony Bishopp, Darren Wells, Nicolaus von Wirén, Malcolm Bennett, Ranjan Swarup
article
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-03851-3⟩
Accès au texte intégral et bibtex
https://hal.archives-ouvertes.fr/hal-02386622/file/2018_Bhosale_Nat_Comm_1.pdf BibTex
titre
Transcriptional induction of cell wall remodelling genes is coupled to microtubule-driven growth isotropy at the shoot apex in Arabidopsis
auteur
Alessia Armezzani, Ursula Abad, Olivier Ali, Amélie Andres Robin, Laetitia Vachez, Antoine Larrieu, Ewa Mellerowicz, Ludivine Taconnat, Virginie Battu, Thomas Stanislas, Mengying Liu, Teva Vernoux, Jan Traas, Massimiliano Sassi
article
Development (Cambridge, England), Company of Biologists, 2018, 145 (11), ⟨10.1242/dev.162255⟩
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https://hal.archives-ouvertes.fr/hal-01894645/file/CA51A8F3-17C5-40B9-8066-171241C3A773.pdf BibTex
titre
The Rosa genome provides new insights into the domestication of modern roses
auteur
Olivier Raymond, Jerome Gouzy, Jérémy Just, Hélène Badouin, Marion Verdenaud, Arnaud Lemainque, Philippe Vergne, Sandrine Moja, Nathalie Choisne, Caroline Pont, Sébastien Carrere, Jean-Claude Caissard, Arnaud Couloux, Ludovic Cottret, Jean-Marc Aury, Judit Szécsi, David Latrasse, Mohammed Madoui, Léa Francois, Xiaopeng Fu, Shu-Hua Yang, Annick Dubois, Florence Piola, Antoine Larrieu, Magali Perez, Karine Labadie, Lauriane Perrier, Benjamin Govetto, Yoan Labrousse, Priscilla Villand, Claudia Bardoux, Véronique Boltz, Celine Lopez-Roques, Pascal Heitzler, Teva Vernoux, Michiel Vandenbussche, Hadi Quesneville, Adnane Boualem, Abdelhafid Bendahmane, Chang Liu, Manuel Le Bris, Jérôme Salse, Sylvie Baudino, Moussa Benhamed, Patrick Wincker, Mohammed Bendahmane
article
Nature Genetics, Nature Publishing Group, 2018, 50 (6), pp.772-777. ⟨10.1038/s41588-018-0110-3⟩
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https://hal-amu.archives-ouvertes.fr/hal-01798003/file/publi18-lipm-016_1.pdf BibTex
titre
The growth of a stable stationary structure: coordinating cell behavior and patterning at the shoot apical meristem
auteur
Jekaterina Truskina, Teva Vernoux
article
Current Opinion in Plant Biology, Elsevier, 2018, 41, pp.83-88. ⟨10.1016/j.pbi.2017.09.011⟩
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titre
Systems biology of meristems: an interview with Teva Vernoux
auteur
Teva Vernoux
article
BMC Biology, BioMed Central, 2018, 16, ⟨10.1186/s12915-018-0591-7⟩
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Preprints, Working Papers, ...

titre
From spatio-temporal morphogenetic gradients to rhythmic patterning at the shoot apex
auteur
Carlos Galvan-Ampudia, Guillaume Cerutti, Jonathan Legrand, Romain Azaïs, Geraldine Brunoud, Steven Moussu, Christian Wenzl, Jan Lohmann, Christophe Godin, Teva Vernoux
article
2018
Accès au texte intégral et bibtex
https://hal.inria.fr/hal-01937928/file/469718.full.pdf BibTex

2017

Journal articles

titre
Structure of the Arabidopsis TOPLESS corepressor provides insight into the evolution of transcriptional repression
auteur
Raquel Martin-Arevalillo, Max H. Nanao, Antoine Larrieu, Thomas Vinos-Poyo, David Mast, Carlos Galvan-Ampudia, Geraldine Brunoud, Teva Vernoux, Renaud Dumas, François Parcy
article
Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2017, 114 (30), pp.8107-8112. ⟨10.1073/pnas.1703054114⟩
Accès au texte intégral et bibtex
https://hal.archives-ouvertes.fr/hal-01605698/file/2017_Martin-Arevalillo_PNAS_1.pdf BibTex
titre
Auxin 2016: a burst of auxin in the warm south of China
auteur
Teva Vernoux, Stephanie Robert
article
Development (Cambridge, England), Company of Biologists, 2017, 144 (4), pp.533-540. ⟨10.1242/dev.144790⟩
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2016

Journal articles

titre
A stochastic multicellular model identifies biological watermarks from disorders in self-organized patterns of phyllotaxis
auteur
Yassin Refahi, Géraldine Brunoud, Etienne Farcot, Alain Jean-Marie, Minna Pulkkinen, Teva Vernoux, Christophe Godin
article
eLife, eLife Sciences Publication, 2016, 71, pp.50. ⟨10.7554/eLife.14093.001⟩
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https://hal.inria.fr/hal-01390155/file/Refahi2016%20eLife.pdf BibTex
titre
A Glimpse beyond Structures in Auxin-Dependent Transcription.
auteur
François Parcy, Teva Vernoux, Renaud Dumas
article
Trends in Plant Science, Elsevier, 2016, 21 (7), pp.574-583. ⟨10.1016/j.tplants.2016.02.002⟩
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titre
Q&A: How does jasmonate signaling enable plants to adapt and survive?
auteur
Antoine Larrieu, Teva Vernoux
article
BMC Biology, BioMed Central, 2016, 14, pp.1-8. ⟨10.1186/s12915-016-0308-8⟩
Accès au texte intégral et bibtex
https://hal.inrae.fr/hal-02641176/file/2016_Larrieu_BMC%20Biology_1.pdf BibTex
titre
Reproductive failure in Arabidopsis thaliana under transient carbohydrate limitation: flowers and very young siliques are jettisoned and the meristem is maintained to allow successful resumption of reproductive growth
auteur
Martin A. Lauxmann, Maria G. Annunziata, Geraldine Brunoud, Vanessa Wahl, Andrzej Koczut, Asdrubal Burgos, Justyna J. Olas, Eugenia Maximova, Christin Abel, Armin Schlereth, Aleksandra M. Soja, Oliver E. Bläsing, John E. Lunn, Teva Vernoux, Mark Stitt
article
Plant, Cell and Environment, Wiley, 2016, 39 (4), pp.745-767. ⟨10.1111/pce.12634⟩
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titre
Phyllotaxis: from patterns of organogenesis at the meristem to shoot architecture
auteur
Carlos Galvan-­‐ampudia, Anaïs Chaumeret, Christophe Godin, Teva Vernoux
article
Wiley Interdisciplinary Reviews: Developmental Biology, Wiley, 2016, 5 (4), pp.460 - 473. ⟨10.1002/wdev.231⟩
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https://hal.archives-ouvertes.fr/hal-01413095/file/WIRE_Galvan-Ampudia_%26_Chaumeret.pdf BibTex
titre
Modelling the influence of dimerisation sequence dissimilarities on the auxin signalling network
auteur
Jonathan Legrand, Jean-Benoist Leger, Stephane Robin, Teva Vernoux, Yann Guédon
article
BMC Systems Biology, BioMed Central, 2016, 10 (22), pp.17. ⟨10.1186/s12918-016-0254-7⟩
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https://hal.inria.fr/hal-01361020/file/LegrandLegerRobinVernouxGuedon2016.pdf BibTex

Preprints, Working Papers, ...

titre
Semi-parametric Markov Tree for cell lineage analysis
auteur
Pierre Fernique, Jonathan Legrand, Jean-Baptiste Durand, Yann Guédon
article
2016
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2015

Journal articles

titre
Reporters for sensitive and quantitative measurement of auxin response
auteur
Che-Yang Liao, Wouter Smet, Geraldine Brunoud, Saiko Yoshida, Teva Vernoux, Dolf Weijers
article
Nature Methods, Nature Publishing Group, 2015, 12 (3), ⟨10.1038/NMETH.3279⟩
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titre
Transcriptional control of tissue formation throughout root development
auteur
Miguel A. Moreno-Risueno, Rosangela Sozzani, Galip Gürkan Yardımcı, Jalean J. Petricka, Teva Vernoux, Ikram Blilou, Jose Alonso, Cara M. Winter, Uwe Ohler, Ben Scheres, Philip N. Benfey
article
Science, American Association for the Advancement of Science, 2015, 350 (6259), pp.426-430. ⟨10.1126/science.aad1171⟩
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titre
A modular analysis of the auxin signalling network
auteur
Etienne Farcot, Cyril Lavedrine, Teva Vernoux
article
PLoS ONE, Public Library of Science, 2015, 10 (3), ⟨10.1371/journal.pone.0122231⟩
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https://hal.inrae.fr/hal-02632134/file/2015_Farcot_PlosOne_1.pdf BibTex
titre
Modeling plant development: from signals to gene networks
auteur
Cyril Lavedrine, Etienne Farcot, Teva Vernoux
article
Current Opinion in Plant Biology, Elsevier, 2015, 27, pp.148-153. ⟨10.1016/j.pbi.2015.07.002⟩
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titre
Three ancient hormonal cues co-ordinate shoot branching in a moss
auteur
Yoan Coudert, Wojtek Palubicki, Karin Ljung, Ondrej Novak, Ottoline Leyser, Jill Harrison
article
eLife, eLife Sciences Publication, 2015
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https://hal.archives-ouvertes.fr/hal-02999193/file/2015_eLife_Coudert.pdf BibTex
titre
Meristem size contributes to the robustness of phyllotaxis in Arabidopsis
auteur
Benoit Landrein, Yassin Refahi, Fabrice Besnard, Nathan Hervieux, Vincent Mirabet, Arezki Boudaoud, Teva Vernoux, Olivier Hamant
article
Journal of Experimental Botany, Oxford University Press (OUP), 2015, 66 (5), pp.1317-1324. ⟨10.1093/jxb/eru482⟩
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titre
Overexpression of the arabidopsis thaliana signalling peptide TAXIMIN1 affects lateral organ development
auteur
Janine Colling, Takayuki Tohge, Rebecca de Clercq, Geraldine Brunoud, Teva Vernoux, Alisdair Fernie, Nokwanda Makunga, Alain Goossens, Laurens Pauwels
article
Journal of Experimental Botany, Oxford University Press (OUP), 2015, 66 (17), pp.5337-5349. ⟨10.1093/jxb/erv291⟩
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titre
A fluorescent hormone biosensor reveals the dynamics of jasmonate signalling in plants
auteur
Antoine Larrieu, Antony Champion, Jonathan Legrand, Julien Lavenus, David Mast, Geraldine Brunoud, Jaesung Oh, Soazig Guyomarc'H, Maxime Pizot, Edward E. Farmer, Colin Turnbull, Teva Vernoux, Malcolm J. Bennett, Laurent Laplaze
article
Nature Communications, Nature Publishing Group, 2015, 6, pp.1-8. ⟨10.1038/ncomms7043⟩
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https://hal.inrae.fr/hal-02637267/file/2015_Larrieu_Nature%20Communication_1.pdf BibTex
titre
Mechanical stress contributes to the expression of the STM homeobox gene in Arabidopsis shoot meristems
auteur
Benoit Landrein, Annamaria Kiss, Massimiliano Sassi, Aurélie Chauvet, Pradeep Das, Millan Cortizo, Patrick Laufs, Seiji Takeda, Mitsuhiro Aida, Jan Traas, Teva Vernoux, Arezki Boudaoud, Olivier Hamant
article
eLife, eLife Sciences Publication, 2015, 4, pp.1-27. ⟨10.7554/eLife.07811⟩
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https://hal.inrae.fr/hal-02631439/file/Landrein2015_1.pdf BibTex

Book sections

titre
Comparison of plant hormone signalling systems
auteur
Antoine Larrieu, Teva Vernoux
article
Plant Hormone Signalling, 58, Portland Press, pp.17, 2015, Essays in Biochemistry, ⟨10.1042/BSE0580165⟩
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2014

Journal articles

titre
An Auxin-Mediated Shift toward Growth Isotropy Promotes Organ Formation at the Shoot Meristem in Arabidopsis
auteur
Massimiliano Sassi, Olivier Ali, Frédéric Boudon, Gladys Cloarec, Ursula Abad, Coralie Cellier, Xu Chen, Benjamin Gilles, Pascale Milani, Jìrí Friml, Teva Vernoux, Christophe Godin, Olivier Hamant, Jan Traas
article
Current Biology - CB, Elsevier, 2014, 24 (19), pp.2335-2342. ⟨10.1016/j.cub.2014.08.036⟩
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https://hal.inria.fr/hal-01074821/file/Sassi2014-2.pdf BibTex
titre
Plasma membrane H+-ATPase regulation is required for auxin gradient formation preceding phototropic growth
auteur
Tim Hohm, Emilie Demarsy, Clement Quan, Laure Allenbach Petrolati, Tobias Preuten, Teva Vernoux, Sven Bergmann, Christian Fankhauser
article
Molecular Systems Biology, EMBO Press, 2014, 10 (9), pp.1-11. ⟨10.15252/msb.20145247⟩
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https://hal.inrae.fr/hal-02631453/file/2014_Hohm_Molecular_Systems_Biology_1.pdf BibTex
titre
Auxin depletion from leaf primordia contributes to organ patterning
auteur
Jiyan Qi, Ying Wang, Ting Yu, Alexandre Cunha, Binbin Wu, Teva Vernoux, Elliot Meyerowitz, Yuling Jiao
article
Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2014, 111 (52), pp.18769 - 18774. ⟨10.1073/pnas.1421878112⟩
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titre
Structural basis for oligomerization of auxin transcriptional regulators.
auteur
Max H Nanao, Thomas Vinos-Poyo, Géraldine Brunoud, Emmanuel Thévenon, Meryl Mazzoleni, David Mast, Stéphanie Lainé, Shucai Wang, Gretchen Hagen, Hanbing Li, Thomas J Guilfoyle, François Parcy, Teva Vernoux, Renaud Dumas
article
Nature Communications, Nature Publishing Group, 2014, 5, pp.3617. ⟨10.1038/ncomms4617⟩
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https://hal.archives-ouvertes.fr/hal-00984482/file/2013_Nanao_nature%20communications_1.pdf BibTex
titre
Signal integration by GSK3 kinases in the root
auteur
Carlos S. Galvan-Ampudia, Teva Vernoux
article
Nature Cell Biology, Nature Publishing Group, 2014, 16 (1), pp.21-23. ⟨10.1038/ncb2898⟩
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titre
Auxin depletion from the leaf axil conditions competence for axillary meristem formation in Arabidopsis and tomato
auteur
Quan Wang, Wouter Kohlen, Susanne Rossmann, Teva Vernoux, Klaus Theres
article
The Plant cell, American Society of Plant Biologists (ASPB), 2014, 26 (5), pp.2068-2079. ⟨10.1105/tpc.114.123059⟩
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titre
Analysis of 3D gene expression patterns in plants using whole-mount RNA in situ hybridization
auteur
Frédérique Rozier, Vincent Mirabet, Teva Vernoux, Pradeep Das
article
Nature Protocols, Nature Publishing Group, 2014, 9 (10), pp.2464-2475. ⟨10.1038/nprot.2014.162⟩
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titre
The AHP6 cytokinin signaling inhibitor mediates an auxin-cytokinin crosstalk that regulates the timing of organ initiation at the shoot apical meristem
auteur
Fabrice Besnard, Frédérique Rozier, Teva Vernoux
article
Plant Signaling and Behavior, Taylor & Francis, 2014, 9 (4), ⟨10.4161/psb.28788⟩
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https://hal.archives-ouvertes.fr/hal-01601710/file/Besnard%20F%2C%20Vernoux%20T-PSB%202014_AHP6%20and%20auxin%20crosstalk_1.pdf BibTex
titre
Cytokinin signalling inhibitory fields provide robustness to phyllotaxis
auteur
Fabrice Besnard, Yassin Refahi, Valérie Morin, Benjamin Marteaux, Géraldine Brunoud, Pierre Chambrier, Frédérique Rozier, Vincent Mirabet, Jonathan Legrand, Stéphanie Lainé, Emmanuel Thévenon, Etienne Farcot, Coralie Cellier, Pradeep Das, Anthony Bishopp, Renaud Dumas, François Parcy, Ykä Helariutta, Arezki Boudaoud, Christophe Godin, Jan Traas, Yann Guédon, Teva Vernoux
article
Nature, Nature Publishing Group, 2014, 505 (7483), pp.417-421. ⟨10.1038/nature12791⟩
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titre
Plant roots use a patterning mechanism to position lateral root branches toward available water
auteur
Yun Bao, Pooja Aggarwal, Neil E. Robbins, Craig J. Sturrock, Mark C. Thompson, Han Qi Tan, Cliff Tham, Lina Duan, Pedro L. Rodriguez, Teva Vernoux, Sacha J. Mooney, Malcolm J. Bennett, Jose R. Dinneny
article
Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2014, 111 (25), pp.9319-9324. ⟨10.1073/pnas.1400966111⟩
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titre
Systems analysis of auxin transport in the Arabidopsis root apex
auteur
Leah R. Band, Darren M. Wells, John A. Fozard, Teodor Ghetiu, Andrew P. French, Michael P. Pound, Michael H. Wilson, Lei Yu, Wenda Li, Hussein I. Hijazi, Jaesung Oh, Simon P. Pearce, Miguel A. Perez-Amador, Jeonga Yun, Eric Kramer, Jose M. Alonso, Christophe Godin, Teva Vernoux, T. Charlie Hodgman, Tony P. Pridmore, Ranjan Swarup, John R. King, Malcolm J. Bennett
article
The Plant cell, American Society of Plant Biologists (ASPB), 2014, 26 (3), pp.862-875. ⟨10.1105/tpc.113.119495⟩
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2013

Journal articles

titre
Halotropism Is a Response of Plant Roots to Avoid a Saline Environment
auteur
Carlos S. Galvan-Ampudia, Magdalena M. Julkowska, Essam Darwish, Jacinto Gandullo, Ruud A. Korver, Geraldine Brunoud, Michel A. Haring, Teun Munnik, Teva Vernoux, Christa Testerink
article
Current Biology - CB, Elsevier, 2013, 23 (20), pp.2044 - 2050. ⟨10.1016/j.cub.2013.08.042⟩
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titre
Auxin and self-organization at the shoot apical meristem
auteur
Massimiliano Sassi, Teva Vernoux
article
Journal of Experimental Botany, Oxford University Press (OUP), 2013, 64 (9), pp.2579 - 2592. ⟨10.1093/jxb/ert101⟩
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titre
Biosensors for phytohormone quantification: challenges, solutions, and opportunities
auteur
Darren M. Wells, Laurent Laplaze, Malcolm J. Bennett, Teva Vernoux
article
Trends in Plant Science, Elsevier, 2013, 18 (5), pp.244 - 249. ⟨10.1016/j.tplants.2012.12.005⟩
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titre
Pattern identification and characterization reveal permutations of organs as a key genetically controlled property of post-meristematic phyllotaxis
auteur
Yann Guédon, Yassin Refahi, Fabrice Besnard, Etienne Farcot, Christophe Godin, Teva Vernoux
article
Journal of Theoretical Biology, Elsevier, 2013, 338, pp.94-110. ⟨10.1016/j.jtbi.2013.07.026⟩
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titre
Plant hormone signaling during development: insights from computational models
auteur
Marina Oliva, Etienne Farcot, Teva Vernoux
article
Current Opinion in Plant Biology, Elsevier, 2013, 16 (1), pp.19-24. ⟨10.1016/j.pbi.2012.11.006⟩
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https://hal.inria.fr/hal-00850918/file/COPB-revision.pdf BibTex

2012

Journal articles

titre
A Light-Regulated Genetic Module Was Recruited to Carpel Development in Arabidopsis following a Structural Change to SPATULA
auteur
Matthieu Reymond, Geraldine Brunoud, Aurélie Chauvet, Jaime F. Martinez-Garcia, Marie-Laure Magniette, Françoise Monéger, C.P. Scutt
article
The Plant cell, American Society of Plant Biologists (ASPB), 2012, 24 (7), pp.2812 - 2825. ⟨10.1105/tpc.112.097915⟩
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titre
Root gravitropism is regulated by a transient lateral auxin gradient controlled by a tipping-point mechanism.
auteur
Leah R Band, Darren M Wells, Antoine Larrieu, Jianyong Sun, Alistair M Middleton, Andrew P French, Géraldine Brunoud, Ethel Mendocilla Sato, Michael H Wilson, Benjamin Péret, Marina Oliva, Ranjan Swarup, Ilkka Sairanen, Geraint Parry, Karin Ljung, Tom Beeckman, Jonathan M Garibaldi, Mark Estelle, Markus R Owen, Kris Vissenberg, T Charlie Hodgman, Tony P Pridmore, John R King, Teva Vernoux, Malcolm J Bennett
article
Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2012, 109 (12), pp.4668-73. ⟨10.1073/pnas.1201498109⟩
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titre
A novel sensor to map auxin response and distribution at high spatio-temporal resolution
auteur
Geraldine Brunoud, Darren M. Wells, Marina Oliva, Antoine Larrieu, Vincent Mirabet, Amy H. Burrow, Tom Beeckman, Stefan Kepinski, Jan Traas, Malcolm J. Bennett, Teva Vernoux
article
Nature, Nature Publishing Group, 2012, 482 (7383), pp.103 - U132. ⟨10.1038/nature10791⟩
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titre
COP1 mediates the coordination of root and shoot growth by light through modulation of PIN1-and PIN2-dependent auxin transport in Arabidopsis
auteur
Massimiliano Sassi, Yanfen Lu, Yonghong Zhang, Juan Wang, Pankaj Dhonukshe, Ikram Blilou, Minqiu Dai, Juan Li, Ximing Gong, Yvon Jaillais, Xuhong Yu, Jan Traas, Ida Ruberti, Haiyang Wang, Ben Scheres, Teva Vernoux, Jian Xu
article
Development (Cambridge, England), Company of Biologists, 2012, 139 (18), pp.3402 - 3412. ⟨10.1242/dev.078212⟩
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titre
Modeling regulatory networks to understand plant development: small is beautiful
auteur
Alistair Middleton, Etienne Farcot, Markus Owen, Teva Vernoux
article
The Plant cell, American Society of Plant Biologists (ASPB), 2012, 24 (10), pp.3876-3891. ⟨10.1105/tpc.112.101840⟩
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titre
Noise and robustness in phyllotaxis
auteur
Vincent Mirabet, Fabrice Besnard, Teva Vernoux, Arezki Boudaoud
article
PLoS Computational Biology, Public Library of Science, 2012, 8 (2), ⟨10.1371/journal.pcbi.1002389⟩
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https://hal.inrae.fr/hal-02648616/file/2012_Mirabet_journal%20pcbi_1.pdf BibTex

2011

Journal articles

titre
Organogenesis from stem cells in planta: multiple feedback loops integrating molecular and mechanical signals
auteur
Fabrice Besnard, Teva Vernoux, Olivier Hamant
article
Cellular and Molecular Life Sciences, Springer Verlag, 2011, 68 (17), pp.2885-2906. ⟨10.1007/s00018-011-0732-4⟩
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titre
The auxin signalling network translates dynamic input into robust patterning at the shoot apex
auteur
Teva Vernoux, Géraldine Brunoud, Etienne Farcot, Valérie Morin, Hilde Daele, Jonathan Legrand, Marina Oliva, Pradeep Das, Antoine Larrieu, Darren Wells, Yann Guédon, Lynne Armitage, Franck Picard, Soazig Guyomarch, Coralie Cellier, Geraint Parry, Rachil Koumproglou, John H. Doonan, Mark Estelle, Christophe Godin, Stefan Kepinski, Malcolm Bennett, Lieven Veylder, Jan Traas
article
Molecular Systems Biology, EMBO Press, 2011, 7 (508), ⟨10.1038/msb.2011.39⟩
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https://hal.inria.fr/hal-00828880/file/msb201139.pdf BibTex
titre
Positional information by differential endocytosis splits auxin response to drive arabidopsis root meristem growth
auteur
Luca Santuari, Emanuele Scacchi, Antia Rodriguez-Villalon, Paula Salinas, Esther M. N. Dohmann, Geraldine Brunoud, Teva Vernoux, Richard S. Smith, Christian S. Hardtke
article
Current Biology - CB, Elsevier, 2011, 21 (22), pp.1918 - 1923. ⟨10.1016/j.cub.2011.10.002⟩
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2010

Journal articles

titre
Interplay between the NADP-linked thioredoxin and glutathione systems in Arabidopsis auxin signaling.
auteur
Talaat Bashandy, Jocelyne Guilleminot, Teva Vernoux, David Caparros-Ruiz, Karin Ljung, Yves Meyer, Jean-Philippe Reichheld
article
The Plant cell, American Society of Plant Biologists (ASPB), 2010, 22 (2), pp.376-91. ⟨10.1105/tpc.109.071225⟩
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titre
Cyclin-dependent kinase activity maintains the shoot apical meristem cells in an undifferentiated state
auteur
Tarik Gaamouche, Carmem-Lara de O. Manes, Dorota Kwiatkowska, Barbara Berckmans, Rachel Koumproglou, Sara Maes, Tom Beeckman, Teva Vernoux, John H. Doonan, Jan Traas, Dirk Inzé, Lieven de Veylder
article
Plant Journal, Wiley, 2010, 64 (1), pp.26 - 37. ⟨10.1111/j.1365-313X.2010.04317.x⟩
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titre
Auxin at the shoot apical meristem
auteur
Teva Vernoux, Fabrice Besnard, Jan Traas
article
Cold Spring Harbor Perspectives in Biology, Cold Spring Harbor Laboratory Press, 2010, 2 (4), pp.a001487. ⟨10.1101/cshperspect.a001487⟩
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https://hal.archives-ouvertes.fr/hal-01608647/file/cshperspect_1.a001487 BibTex

2009

Journal articles

titre
Floral stem cell termination involves the direct regulation of AGAMOUS by PERIANTHIA
auteur
Pradeep Das, T. Ito, F. Wellmer, Teva Vernoux, A. Dedieu, Jan Traas, Em Meyerowitz
article
Development (Cambridge, England), Company of Biologists, 2009, 136 (10), pp.1605-1611
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2006

Journal articles

titre
Whole-genome analysis of the SHORT-ROOT developmental pathway in Arabidopsis
auteur
Mp Levesque, Teva Vernoux, W. Busch
article
PLoS Biology, Public Library of Science, 2006, 4, pp.739-752. ⟨10.1371/journal.pbio.0040143⟩
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https://hal.archives-ouvertes.fr/hal-00412464/file/2008_Levesque_Journal-pbio_1.pdf BibTex


Scientific context:

From dynamic patterning to global plant architecture

Research in the SIGNAL team addresses a question central to developmental biology: how do non-linear interactions at multiple scales (molecule, cell, tissue, organism) lead to coordinated cell behaviours and to the emergence of precise forms in multi-cellular organisms?
For instance, many of our projects are connected to phyllotaxis, the geometric arrangement of leaves, branches and flowers along stems, which shows striking regularities and puzzling mathematical properties. We use both seed plants and mosses as model systems, and interdisciplinary approaches to tackle this question. To capture how developmental dynamics link genotypes to phenotypes, our approaches are deeply rooted in functional genetics and rely on quantitative phenotyping at all scales (e.g. using confocal imaging), real-time observations and computational modelling.

More specific research themes focus on:
 Hormonal signals and developmental dynamics at the shoot apical meristem
 Genetic control and robustness of inflorescence architecture
 Hormonal control and evolution of branching forms
 Multi-scale imaging solutions for the quantitative analysis of forms

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preserveAspectRatio="none"/></svg>' width='640' height='353' alt="Signal_TeamRetreat_2019" title="Signal_TeamRetreat_2019" class='adapt-img adapt-img-multilayers blur' onmousedown='adaptImgFix(this)' />

Hormonal signals and developmental dynamics at the shoot apical meristem

Project leader: Teva Vernoux
Persons involved: Géraldine Brunoud (CNRS Research Engineer), Carlos Galván-Ampudia (Senior postdoc), Raquel Martin-Arevalillo (Postdoc), Estefania Pavesi (PhD Student; co-supervisor: Matias Zurbriggen, University of Düsseldorf), Marketa Pernisova (Postdoc), Bihai Shi (Postdoc).

The shoot apical meristem, a specialized tissue containing a stem cell niche, produces new lateral organs throughout the life of the plant. Here, we investigate how spatio-temporal distribution of hormonal signals and hormone signalling activity contribute to reiterative patterning at the shoot apical meristem.

To do so, we follow a number of complementary lines of research aiming to:
 Obtain a quantitative understanding of how the spatio-temporal distribution of auxin is controlled;
 Analyze the gene network controlling the response to auxin in space and time;
 Understand how symplasmic connections contribute to hormone distribution and patterning;
 Understand how hormones act in controlling growth at the shoot apical meristem and how this contributes to the dynamics of patterning;
 Understand the molecular mechanisms allowing auxin to act in cell fate determination;
 Decipher the molecular basis of auxin-cytokinin interactions during organ patterning at the shoot apical meristem.

We use approaches ranging from quantitative imaging, genomics, genetics to synthetic biology and computational modelling.

Main collaborators: Patrick Achard (IPMB Strasbourg), Malcolm Bennett (University of Nottingham), Anthony Bishopp (University of Nottingham), Siobhan Brady (UC Davis), Renaud Dumas (LPCV Grenoble), Christophe Godin (RDP), Jan Lohman (University of Heidelberg), François Parcy (LPCV Grenoble), François Roudier (RDP), Lyuba Ryabova (IPMB Strasbourg), Dolf Weijers (Wagenigen University), Matias Zurbriggen (University of Düsseldorf)

Genetic control and robustness of inflorescence architecture

Project leaders: Fabrice Besnard and Teva Vernoux
Persons involved: Sana Dieudonné (Ph.D Student), Stéphanie Lainé (INRA Research technician)

Here, we aim to identify key genetic mechanisms controlling plant architecture without prior assumptions. First, we are searching for plants from varied genetic backgrounds with altered shoot architecture traits indicating either a perturbation at the shoot apical meristem and/or a change in the robustness of these traits (i.e. where the variance of the trait is modified). Second, we are aiming to identify the genetic basis explaining the altered phenotypes. We expect to discover novel genes or to shed new light on how known genes act in the dynamics of plant developmental systems. When possible, we work with natural genetic variations that allow us to question how generic are the mechanisms found in laboratory lines and how phenotypic changes occur in natural populations and during evolution.

Ongoing projects are:
  Forward genetics of Arabidopsis thaliana mutants affected in organogenesis and phyllotaxis (S. Laine & F. Besnard / past member: A. Chaumeret)
We are currently investigating a few uncharacterized mutants isolated from Versailles stock center, affected in organogenesis and phyllotaxis. These mutants are in a different genetic background than the widely used Columbia‑0 accession.

  Natural variation of phyllotaxis robustness (F. Besnard)
Despite its regular nature, we showed that inflorescence phyllotaxis shows substantial variations in different genetic backgrounds. Studying those variations can reveal biological watermarks of phyllotaxis and indicate how cell behaviours are coordinated in space and time to generate phyllotactic patterns. We are currently screening different natural accessions to characterize the perturbation levels of their phyllotaxis.

 Coordination of organ identities during rapid phase transition (S. Dieudonné)
Flowering plants switch rapidly from vegetative to floral states when they start producing flowers. In Brassicaceae, including the model plant Arabidopsis thaliana, shoots stop producing basic units comprising a leaf and a branch to make only flowers. No intermediate forms are produced. Strong evidence indicates that the leaf (also called ’bract’) is suppressed when the flower arises, through yet unclear mechanisms that evolved in Brassicaceae. We identified a genetic background in Arabidopsis in which some bracts are associated with flowers at the floral transition. We are currently characterizing the genetic variations that disturb the robust coordination between bracts and flowers upon the floral transition.

Hormonal control and evolution of branching forms

Project leader: Yoan Coudert
Persons involved: Elsa Véron (PhD student), Stéphanie Laine (INRA Research technician), Moira Courseaux (M2 Student)

A key aim in biology is to understand which developmental and genetic changes contributed to the evolution of form through time. In plants, the varied branching patterns emerging from the coordinated activity of meristems at the shoot tips is a key determinant of shape diversity. Hormonal cues have been shown to play a major role in branching control in distinct plant lineages. Here, we aim to understand (1) how the interplay between hormonal cues regulates branch patterning and (2) how this interplay has been remodelled in evolution to generate architectural diversity in plants. We use mosses as model organisms.

Ongoing projects are:
 Evolution of branching control and meristem function in plants
Branch patterning in the shoot is coordinated at the whole plant level by three hormones: auxin, cytokinin and strigolactone. These molecules existed before the divergence between mosses and vascular plants, and were independently recruited in both plant lineages to control leafy shoot branching. In vascular plants, including Arabidopsis thaliana, long-range auxin transport is mediated by PIN proteins and is a key regulator of branching. In the moss Physcomitrium patens, pharmacological inhibitor and mutant analysis experiments have shown that homologues of PIN genes have only a minor role in shoot branching. Instead, apolar and diffusive auxin transport has been proposed as a novel regulator of branching in moss, and could be mediated by callose-regulated plasmodesmal gating. Our goal is to understand how hormonal cues coordinate branching in the moss Physcomitrium patens .

 Polarity control and shoot development from a single apical cell
Phyllotaxis, the geometry of leaf arrangement around stems, determines plant architecture. Molecular interactions coordinating the formation of phyllotactic patterns have mainly been studied in multicellular shoot apical meristems of flowering plants. Phyllotaxis evolved independently in the major land plant lineages. In mosses, it arises from a single apical cell, raising the question of how the polarity and asymmetric divisions of a single-celled meristem create phyllotactic patterns and whether associated genetic processes are shared across lineages. We use the model moss, Physcomitrium patens, to investigate this fundamental biological problem and identify the mechanisms governing shoot apical cell activity.

Multiscale imaging solutions for the quantitative analysis of forms

Project leaders: Fabrice Besnard, Yoan Coudert, Teva Vernoux
Persons involved: Géraldine Brunoud (CNRS Research Engineer), Julie Charlaix (Engineer), Jonathan Legrand (CNRS Research Engineer), Carlos Galván-Ampudia (Senior postdoc), Bihai Shi (Postdoc)

A limiting factor for understanding the dynamics of shape emergence is the capacity to quantify developmental parameters in time and space at different scales. In order to capture these developmental parameters, the SIGNAL team has been and continue developing:
 Biosensors for hormones;
 Open-source robotic solution to automate the phenotyping of aerial parts of plants (and notably Arabidopsis) with high precision (and reasonable through-put);
 Software solutions for quantitative image analysis.

Main collaborators: Patrick Achard (IPMB Strasbourg), Christophe Godin (RDP), Peter Hannappe (Sony CSL Paris), Jonathan Michin (IAAC Barcelona), Verena Hafner (HU Berlin), Matias Zurbriggen (University of Düsseldorf)

Key publications:

  Coudert Y, Bell NE, Edelin C, Harrison CJ. Multiple innovations underpinned branching form diversification in mosses. New Phytologist, 10.1111/nph.14553 (2017)

  Refahi Y, Brunoud G, Farcot E, Jean-Marie A, Pulkkinen M, Vernoux T*, Godin C * (2016). A stochastic multicellular model identifies biological watermarks from disorders in self-organized patterns of phyllotaxis. eLife 5 :e14093

  Larrieu A, Champion A, Legrand J, Lavenus J, Mast D, Brunoud G, Oh J, Guyomarc’h S, Pizot M, Farmer EE, Turnbull C, Vernoux T*, Bennett M* & Laplaze L* (2015) A novel fluorescent hormone biosensor reveals the dynamics of jasmonate signaling in plants. Nature Communications 6:6043

  Coudert Y, Palubicki W, Ljung K, Novak O, Leyser O, Harrison CJ. Three ancient hormonal cues coordinate shoot branching in the moss Physcomitrella. eLife, 10.7554/eLife.06808 (2015)

  Besnard F, Refahi Y, Morin V, Marteaux B, Brunoud G., Chambrier P, Rozier F, Mirabet V, Legrand J, Lainé S, Thévenon E, Farcot E, Cellier C, Das P, Bishopp A, Dumas R, Parcy F, Helariutta Y, Boudaoud A, Godin C, Traas J, Guédon, Y, Vernoux T* (2014). Cytokinin signalling inhibitory fields provide robustness to phyllotaxis. Nature 505, 417–421

  Brunoud G, Wells DM, Oliva M, Larrieu A, Mirabet V, Burrow AH, Beeckman T, Kepinski S, Traas J, Bennett MJ, Vernoux T* (2012) A novel sensor to map auxin response and distribution at high spatio-temporal resolution. Nature 482: 103-106

Fundings:

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