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Alternative splicing and tumoral progression - D. Auboeuf
Our team is interested in the regulation of alternative splicing, the main process allowing to largely increase the functional diversity of proteins coded by a limited number of genes in higher organisms.
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Apoptosis and Neurogenetics - B. Mollereau
The general goal of our lab is to understand the mechanisms of cell death, ER stress, autophagy and metabolism during development and in neurodegenerative diseases. We characterize those responses in physiological and pathological situations in the Drosophila retina, brain and during spermatogenesis.
Located in Teams
RNA metabolism in immunity and infection (RMI2) - E. Ricci
We are interested in post-transcriptional control mechanisms that regulate gene expression in cells of the immune system and during pathogen infections. Through the use of high-throughput sequencing and biochemical approaches we aim at identifying new regulatory layers that govern immune cell activation and host-pathogen interactions.
Located in Teams
Posttranscriptional Regulation in Infection and Oncogenesis - Jalinot/Mocquet
Our main research interest is to decipher the molecular mechanisms underlying oncogenesis, with a particular interest in the role of genetic instability in the process. Towards this goal we focused our attention on leukemogenesis driven by infection with the human T-cell lymphotropic virus type 1 (HTLV-1).
Located in Teams
Structure and Interactions of Molecular Biosystems - M. Spichty
We apply atomic-level computer simulations and molecular and cellular biology experiments to gain insights into the dynamic structure of proteins and their interactions in living cells. The main goal is to understand the factors that determine the interaction strength between proteins and how the cell modulates these interactions to regulate biological functions.
Located in Teams
Welcome to the RMI2 lab
RNA metabolism in immunity and infection (RMI2)
Located in Teams