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Systems Biology of Decision Making

Systems Biology of Decision Making - O. Gandrillon

"Cells are neither machines nor simple information processing devices. Their specific complexity sometimes led to the idea that they should be treated differently that classical physico-chemical systems. Nevertheless like all living systems cells are rooted within a physico-chemical reality which they can not escape. We therefore argue that cells should be seen and modelled as probabilistic dynamical systems."

Estavoyer, M., Dufeu, M., Ranson, G., Lefort, S., Voeltzel, T., Maguer-Satta, V., Gandrillon, O. and Lepoutre, T. (2024). Modeling relaxation experiments with a mechanistic model of gene expression. BMC Bioinformatics, 25, 270. 

 

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SBDM team in the news: Olivier Gandrillon has been interviewed by Science et Vie (in French) about stochasticity in Biology.

SBDM team in the news: Les principes généraux du déterminisme de la cellule - Olivier Gandrillon et Serge Lebecque - 2021