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Laboratoire de Biologie et Modélisation de la Cellule - UMR 5239 - Inserm 1293

The LBMC is an experimental biology laboratory hosted at ENS de Lyon in a multidisciplinary scientific environment. The laboratory's main subject of study is the cell, which is the most fundamental unit of life.

The 15 research teams aim at integrating diverse aspects of cell life such as proliferation, differentation, and interaction with cellular environment in a normal or pathogenic context. The fundamental research pursued in the laboratory relies on expertise in cellular and molecular biology and integrates interdisciplinary approaches in (bio)computing, (bio)physics and (bio)mathematics.

More details here.

Follow us on Twitter @Lyon_LBMC

Last publications
2023 Schweke H & al, Proteomics Discriminating physiological from (...)
2023 Thangaratnarajah C & al, Nature Communications Expulsion mechanism of the (...)
2023 Sahoo A & al, Structure Transmembrane dimers of type 1 receptors sample (...)
2023 MacCallum J & al, Biophysical Journal An implementation of the Martini coarse-grained (...)
2022 Chen X & al, Anal Chem Mono- and Intralink Filter (Mi-Filter) To Reduce (...) C (...)
2023 Vanlioğlu E & al, J Mol Biol Coevolution-Guided Mapping of the Type VI (...) T (...)
2023 Kandolo O & al, PLoS Pathog Acinetobacter type VI secretion system comprises (...) A (...)
2024 Bongiovanni T & al, Nat Commun Assembly of a unique membrane complex in type VI (...) T (...)
2023 Torcal Garcia G & al, eLife Carm1-arginine methylation of the transcription (...) H (...)
2023 Dumont A & al, BioRxiv Mechanism of homology search expansion during (...) H (...)
2023 Abdulla A & al, Macromolecules Topological Constraints and Finite-Size Effects (...)
2023 Chahar S & al, PLoS Biol Transcription induces context-dependent (...) M (...)
Dynamics and Control of Biological Assemblies and Macromolecular Machines
We are a horizontal team of four researchers in computational biology. We study molecular machines (...) Read more
Complexity, plasticity, and functionality of miRNAs
We elucidate the mechanism of modular layer of post-transcriptional control formed by miRNAs, which (...) Read more
Genome mechanics
DNA is a busy molecule teeming with a zoo of static binders and molecular motors. DNA's (...) Read more
Physical Biology of Chromatin
In close connection with experimental biology, our research addresses generic or specific (...) Read more
Epigenetics and Zygote Formation
The formation of a diploid zygote from two highly different gametes is a critical aspect of sexual (...) Read more
RNA metabolism in immunity and infection (RMI2)
We are interested in post-transcriptional control mechanisms that regulate gene expression in cells (...) Read more
Genetic Complexity of Living Systems
Our research group is interested in the fundamental genetic mechanisms underlying inter-individual (...) Read more
Epigenetic regulation of cell identity and environmental stress responses
We are interested in understanding the role of conserved chromatin marks in the maintenance of (...) Read more
Evolutionary Cell Biology in Nematodes
We investigate unconventional modes of DNA transmission and genome regulation, exploring their (...) Read more
Regulated Cell Death and Genetics of Neurodegeneration
The general goal of our lab is to understand the mechanisms of cell death, ER stress, autophagy and (...) Read more
Quantitative regulatory genomics
Why are individuals different? We address this fundamental question by studying both genetic and (...) Read more
Regulation of Genome Architecture and Dynamics of Splicing (ReGArDS)
Our team is interested in the regulation of alternative splicing, the main process allowing to (...) Read more
Comparative and Integrative Genomics of Organ Development
We compare genomes and transcriptomes to highlight general rules about the development and/or the (...) Read more
Posttranscriptional Regulation in Infection and Oncogenesis
Our main research interest is to decipher the molecular mechanisms underlying oncogenesis, with a (...) Read more
Epithelial differentiation and morphogenesis in Drosophila
Read more
Systems Biology of Decision Making
The molecular mechanisms controlling decision making at the cellular level between self-renewal and (...) Read more
Chromatin Dynamics in Mitotic Chromosome Assembly
The ability of the genome to adopt a dynamic 3D organisation underlies most DNA transactions. The (...) Read more
What else ?
Nena Martin a rejoint l’équipe Lyonnaise de Pint of Science. Nous sommes allées l’interviewer (...)