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Systems biology of signaling and developmental cellular processes

Comparative and Integrative Genomics of Organ Development - S.Pantalacci/M. Semon

We compare genomes and transcriptomes to highlight general rules about the development and/or the evolution of organs. Read more

Epigenetic regulation of cell identity and environmental stress responses - F. Palladino

We are interested in understanding the role of conserved chromatin marks in the maintenance of germline identity and the response to environmental stress. To adress these questions, we are using C. elegans as a model organism. (...) Read more

Epigenetics and Zygote Formation - B. Loppin

The formation of a diploid zygote from two highly different gametes is a critical aspect of sexual reproduction in animals. Notably, the transmission of the paternal genome implies unique chromatin reorganization events that take (...) Read more

Epithelial differentiation and morphogenesis in Drosophila - M. Grammont

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Evolutionary Cell Biology in Nematodes - M. Delattre

We investigate unconventional modes of DNA transmission and genome regulation, exploring their evolutionary origins and consequences. Our primary focus is on nematode species that are lab tractable, enabling seamless integration (...) Read more

Systems Biology of Decision Making - O. Gandrillon

The molecular mechanisms controlling decision making at the cellular level between self-renewal and differentiation are still poorly understood. The central question of our group consists in understanding the molecular mechanisms (...) Read more

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