Welcome to the companion page of our publication:

Nagarajan et al. 2010. PLoS Genetics. Natural Single-Nucleosome Epi-Polymorphisms in Yeast.

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DATASET                SYNOPSIS         SOFTWARE

NucleoMiner : A C package for nucleosome mapping, alignment and SNEP detection.

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NucleoMiner is distributed as an Open Source Software under the General Public Licence. You are free to modify and distribute it. It is provided AS IS and WITHOUT ANY WARRANTY.

INSTALLATION INSTRUCTIONS:

To install NucleoMiner on your UNIX/LINUX computer you need first to install the Genetic Data analysis Library (GDL), which is a dynamic library of useful C functions derived from the GNU Scientific Library.

1. Installing the GDL library.

Download the gdl-1.0.tar.gz archive on your computer. Copy it in a dedicated directory. Go into this directory using the cd command, and then unfold the archive by typing:

tar -xvzf gdl-1.0.tar.gz

This creates a directory called gdl-1.0. You now need to go into this directory and compile the library, by typing:

cd gdl-1.0

./configure

make

Now you need to install the library on your system. This needs root priviledges:

sudo make install

2. Installing NucleoMiner

Download the nucleominer-1.0.tar.gz archive on your computer. Copy it in a dedicated directory. Go into this directory using the cd command, and then unfold the archive by typing:

tar -xvzf nucleominer-1.0.tar.gz

This creates a directory called nucleominer-1.0. You now need to go into this directory and compile the library, by typing:

cd nucleominer-1.0

./configure

make

You can then use the binaries dircetly from this folder (best then is to add the path to this folder in your PATH environment variable). If you want to install nucleominer at the system's level (useful if mutiple users will need it) then type, with root priviledges:

sudo make install

HOW TO USE NUCLEOMINER:

ACCESS ONLINE TUTORIAL

or

DOWNLOAD PDF OF TUTORIAL