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Laboratoire de Biologie et Modélisation de la Cellule - UMR 5239 - Inserm 1293

The LBMC is an experimental biology laboratory hosted at ENS de Lyon in a multidisciplinary scientific environment. The laboratory's main subject of study is the cell, which is the most fundamental unit of life.

The 15 research teams aim at integrating diverse aspects of cell life such as proliferation, differentation, and interaction with cellular environment in a normal or pathogenic context. The fundamental research pursued in the laboratory relies on expertise in cellular and molecular biology and integrates interdisciplinary approaches in (bio)computing, (bio)physics and (bio)mathematics.

More details here.

Follow us on Twitter @Lyon_LBMC

Last publications
2022 Salari H & al, Genome Res Spatial organization of chromosomes leads to (...) C (...)
2022 Methods Mol Biol Polymer Modeling of 3D Epigenome Folding: (...) M (...)
2022 Horard B & al, Curr Biol Paternal transmission of the Wolbachia CidB toxin (...) W (...)
2022 Khatri D & al, Mol Biol Cell Evolutionary divergence of anaphase spindle (...) C (...)
2022 Caron M & al, Life Sci Alliance Loss of SET1/COMPASS methyltransferase activity (...) C (...)
2022 Cluet D & al, Chembiochem Titration of Apparent In-Cellula Affinities of (...) A (...)
2022 Torres-Campana D & al, PLoS Genet Three classes of epigenomic regulators converge (...) T (...)
2022 Belokopytova P & al, Nucleic Acids Res 3DGenBench: a web-server to benchmark (...) M (...)
2022 Hennion M & al, Methods Mol Biol FORK-seq: Single-Molecule Profiling of DNA (...) M (...)
2022 Theulot B & al, Nat Commun Genome-wide mapping of individual replication (...) L (...)
2022 Ceraulo A & al, Blood Adv Prognostic impact of ABCA3 expression in adult (...)
2021 Duveau F & al, Elife Mutational sources of trans-regulatory variation (...) H (...)
News
Teams
Genome mechanics
Homologous recombination is a universal DNA break repair pathway involved in a variety of (...) Read more
Physical Biology of Chromatin
In close connection with experimental biology, our research addresses generic or specific (...) Read more
Epigenetics and Zygote Formation
The formation of a diploid zygote from two highly different gametes is a critical aspect of sexual (...) Read more
RNA metabolism in immunity and infection (RMI2)
We are interested in post-transcriptional control mechanisms that regulate gene expression in cells (...) Read more
Genetic Complexity of Living Systems
Our research group is interested in the fundamental genetic mechanisms underlying inter-individual (...) Read more
Epigenetic regulation of cell identity and environmental stress responses
We are interested in understanding the role of conserved chromatin marks in the maintenance of (...) Read more
Evolutionary Cell Biology in Nematodes
We compare basic cellular functions between closely related species. We ask to what extent the (...) Read more
Regulated Cell Death and Genetics of Neurodegeneration
The general goal of our lab is to understand the mechanisms of cell death, ER stress, autophagy and (...) Read more
Quantitative regulatory genomics
Why are individuals different? We address this fundamental question by studying both genetic and (...) Read more
Regulation of Genome Architecture and Dynamics of Splicing (ReGArDS)
Our team is interested in the regulation of alternative splicing, the main process allowing to (...) Read more
Comparative and Integrative Genomics of Organ Development
We compare genomes and transcriptomes to highlight general rules about the development and/or the (...) Read more
Posttranscriptional Regulation in Infection and Oncogenesis
Our main research interest is to decipher the molecular mechanisms underlying oncogenesis, with a (...) Read more
Epithelial differentiation and morphogenesis in Drosophila
Read more
Systems Biology of Decision Making
The molecular mechanisms controlling decision making at the cellular level between self-renewal and (...) Read more
Chromatin Dynamics in Mitotic Chromosome Assembly
The ability of the genome to adopt a dynamic 3D organisation underlies most DNA transactions. The (...) Read more
 
 
Seminars
Jul 01, 2022
Romain KOSZUL, Institut Pasteur - Paris
Molecular mechanisms and chromatin determinants of chromosome folding in yeast
Jul 20, 2022
Thèse Jélane SAAD - Equipe Auboeuf
Rôle de l’épissage alternatif dans la résistance aux thérapies anti-cancéreuses dans un modèle d’étude de cancer du sein.
Upcoming thesis defenses