Laboratoire de Biologie et Modélisation de la Cellule - UMR 5239 - Inserm 1293
The LBMC is an experimental biology laboratory hosted at ENS de Lyon in a multidisciplinary scientific environment. The laboratory's main subject of study is the cell, which is the most fundamental unit of life.
The 15 research teams aim at integrating diverse aspects of cell life such as proliferation, differentation, and interaction with cellular environment in a normal or pathogenic context. The fundamental research pursued in the laboratory relies on expertise in cellular and molecular biology and integrates interdisciplinary approaches in (bio)computing, (bio)physics and (bio)mathematics.
More details here.
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- Last publications
- 2022 Genome Res Spatial organization of chromosomes leads to (...) C (...)
- 2022 Methods Mol Biol Polymer Modeling of 3D Epigenome Folding: (...) M (...)
- 2022 Curr Biol Paternal transmission of the Wolbachia CidB toxin (...) W (...)
- 2022 Mol Biol Cell Evolutionary divergence of anaphase spindle (...) C (...)
- 2022 Life Sci Alliance Loss of SET1/COMPASS methyltransferase activity (...) C (...)
- 2022 Chembiochem Titration of Apparent In-Cellula Affinities of (...) A (...)
- 2022 PLoS Genet Three classes of epigenomic regulators converge (...) T (...)
- 2022 Nucleic Acids Res 3DGenBench: a web-server to benchmark (...) M (...)
- 2022 Methods Mol Biol FORK-seq: Single-Molecule Profiling of DNA (...) M (...)
- 2022 Nat Commun Genome-wide mapping of individual replication (...) L (...)
- 2022 Blood Adv Prognostic impact of ABCA3 expression in adult (...)
- 2021 Elife Mutational sources of trans-regulatory variation (...) H (...)
- News
- Teams
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Genome mechanicsHomologous recombination is a universal DNA break repair pathway involved in a variety of (...) Read more
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Physical Biology of ChromatinIn close connection with experimental biology, our research addresses generic or specific (...) Read more
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Epigenetics and Zygote FormationThe formation of a diploid zygote from two highly different gametes is a critical aspect of sexual (...) Read more
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RNA metabolism in immunity and infection (RMI2)We are interested in post-transcriptional control mechanisms that regulate gene expression in cells (...) Read more
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Genetic Complexity of Living SystemsOur research group is interested in the fundamental genetic mechanisms underlying inter-individual (...) Read more
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Epigenetic regulation of cell identity and environmental stress responsesWe are interested in understanding the role of conserved chromatin marks in the maintenance of (...) Read more
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Evolutionary Cell Biology in NematodesWe compare basic cellular functions between closely related species. We ask to what extent the (...) Read more
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Regulated Cell Death and Genetics of NeurodegenerationThe general goal of our lab is to understand the mechanisms of cell death, ER stress, autophagy and (...) Read more
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Quantitative regulatory genomicsWhy are individuals different? We address this fundamental question by studying both genetic and (...) Read more
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Regulation of Genome Architecture and Dynamics of Splicing (ReGArDS)Our team is interested in the regulation of alternative splicing, the main process allowing to (...) Read more
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Comparative and Integrative Genomics of Organ DevelopmentWe compare genomes and transcriptomes to highlight general rules about the development and/or the (...) Read more
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Posttranscriptional Regulation in Infection and OncogenesisOur main research interest is to decipher the molecular mechanisms underlying oncogenesis, with a (...) Read more
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Epithelial differentiation and morphogenesis in DrosophilaRead more
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Systems Biology of Decision MakingThe molecular mechanisms controlling decision making at the cellular level between self-renewal and (...) Read more
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Chromatin Dynamics in Mitotic Chromosome AssemblyThe ability of the genome to adopt a dynamic 3D organisation underlies most DNA transactions. The (...) Read more
- Interdisciplinarity
- Dissemination of knowledge
- Seminars
- Jul 01, 2022 Molecular mechanisms and chromatin determinants of chromosome folding in yeast
- Jul 20, 2022 Rôle de l’épissage alternatif dans la résistance aux thérapies anti-cancéreuses dans un modèle d’étude de cancer du sein.
- Upcoming thesis defenses
- Jul 20, 2022
Thèse Jélane SAAD - Equipe Auboeuf
salle Descartes (D2/128) - Equipe Auboeuf