Cellular and molecular pathological processes
RNA metabolism in immunity and infection (RMI2) - E. Ricci
We are interested in post-transcriptional control mechanisms that regulate gene expression in cells of the immune system and during pathogen infections. Through the use of high-throughput sequencing and biochemical approaches we (...) Read more
Regulated Cell Death and Genetics of Neurodegeneration - B. Mollereau
The general goal of our lab is to understand the mechanisms of cell death, ER stress, autophagy and metabolism during development and in neurodegenerative diseases. We characterize those responses in physiological and (...) Read more
Regulation of Genome Architecture and Dynamics of Splicing (ReGArDS) - D. Auboeuf and C. Bourgeois
Our team is interested in the regulation of alternative splicing, the main process allowing to largely increase the functional diversity of proteins coded by a limited number of genes in higher organisms. Read more
Posttranscriptional Regulation in Infection and Oncogenesis - Jalinot/Mocquet
Our main research interest is to decipher the molecular mechanisms underlying oncogenesis, with a particular interest in the role of genetic instability in the process. Towards this goal we focused our attention on leukemogenesis (...) Read more