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You are here: Home / Teams / Epigenetics and Zygote Formation - B. Loppin / Publications / Drosophila protamine-like Mst35Ba and Mst35Bb are required for proper sperm nuclear morphology but are dispensable for male fertility.

Drosophila protamine-like Mst35Ba and Mst35Bb are required for proper sperm nuclear morphology but are dispensable for male fertility.

Samantha Tirmarche, Shuhei Kimura, Laure Sapey-Triomphe, William Sullivan, Frederic Landmann, and Benjamin Loppin (2014)

G3 (Bethesda), 4(11):2241-5.

During spermiogenesis, histones are massively replaced with protamines. A previous report showed that Drosophila males homozygous for a genomic deletion covering several genes including the protamine-like genes Mst35Ba/b are surprisingly fertile. Here, we have precisely deleted the Mst35B locus by homologous recombination, and we confirm the dispensability of Mst35Ba/b for fertility.

 
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