# Statistical Physics and Information Theory

(N. Fourcaud-Trocme, N. Buonviso, CRNL, Lyon) Entropy creation and exchange in non-equilibrium systems is parallel to Information creation, stockage and interactions in dynamical systems. In particular, biological systems are on one side fluctuating and creating information, while on the other side they interact not only with external thermostat and therefore noise, but also with other (possibly similar) systems. We will develop theoretical and actual practical estimation tools to quantify information as well as information fluxes between biological systems. Notably, we will use these tools to decipher not only functional connectivity maps, but also effective connectivity and produce directed graph of interacting systems.