Directory
Philippe BELMONT
| When |
Apr 25, 2018 à 03:45 PM |
|---|---|
| Where |
Amphi Schrödinger |
| Contact |
C. Michel |
Accès aux hétérocycles par catalyse organométallique et photocatalyse visible
We are particularly interested in the use of organometallics (silver, gold, cobalt, ruthenium and rhodium salts) in order to access numerous heterocyclic cores. Part of our work is also devoted to the study of their biological properties, particularly for kinases’ inhibition (development of cyclopenta[c]acridinones exhibiting exquisite biological properties, in collaboration with Dr. L. Meijer).
We therefore develop the original synthesis of phthalazines, isoindolinones,isobenzofuranones, isochomenes, quinolines, acridines, dibenzofurans and carbazoles derivatives, using metal-catalyzed cycloisomerization reactions and, in collaboration with Dr. E. Brachet, visible-light photocatalysis.
http://www.comete.cnrs.fr/heterocycles-peptides/membres/