UMR 5182

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Synthesis and Chiroptical Properties of New Molecular Cages

Stereochemistry and chirality issues have been present for many years in our research activities. We will pursue these studies and develop new enantiopure cage compounds for their intrinsic interest and the development of chiroptical techniques.

ECD and VCD spectroscopies as well as ROA (Raman Optical Activity) will be used to characterize recognition phenomena. This needs to develop new strategies for the synthesis of enantiopure supramolecular hosts, in particular cryptophanes that play a key role in the construction of enantiopure xenon-biosensors.