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L'équipe d'Emiliano Ricci a rejoint le LBMC

Nom de l'équipe : “Métabolisme des ARNs au cours de la réponse immunitaire et de l’infection”

The team of Emiliano Ricci is interested in post-transcriptional control mechanisms that regulate gene expression in cells of the immune system and during pathogen infections. Through the use of high-throughput sequencing and biochemical approaches we aim at identifying new regulatory layers that govern immune cell activation and host-pathogen interactions.

Last publications :

  • Efficient genome editing in primary cells and in vivo using viral-derived “Nanoblades" loaded with Cas9/sgRNA ribonucleoproteins.

Mangeot PE, Rissons V, Fusil F, Marnef A, Laurent E, Blin J, Mournetas V, Massouridès E, Sohier TJM, Corbin A, Aube F, Pinset C, Schaeffer L, Legube G, Cosset FL, Verhoeyen E, Ohlmann T, Ricci EP. BioRxiv. 2017 May 5;45(8):4810-4824. doi: 10.1101/202010

  • microRNAs stimulate translation initiation mediated by HCV-like IRESes.

Mengardi C, Limousin T, Ricci EP, Soto-Rifo R, Decimo D, Ohlmann T. Nucleic Acids Res. 2017 October 5;45(8):4810-4824. doi: 10.1093/nar/gkw1345. PMID: 28077561

  • When mRNA translation meets decay.

Bicknell AA, Ricci EP. Biochem Soc Trans. 2017 Apr 15;45(2):339-351. doi: 10.1042/BST20160243. Review. PMID: 28408474