Annuaire
Vikram Agarwal - Head of mRNA Platform Design Data Science of the mRNA Center of Excellence of Sanofi
Machine learning guided mRNA design for vaccine development
| Quand ? |
Le 22/09/2023, de 11:00 à 12:00 |
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| S'adresser à | Salle des thèses, Equipe Ricci |
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Short abstract:
Here we develop and deploy multiple mRNA codon optimization tools to optimize protein expression from delivered RNA. We also demonstrate Saluki, our state-of-the-art, hybrid convolutional and recurrent deep neural network which relies only upon an mRNA sequence annotated with coding frame and splice sites to predict half-life. Collectively, this group of tools represents the power of machine learning guided approaches in the design of mRNA vaccines.
Contact : Emilinao Ricci