Skip to content. | Skip to navigation

Personal tools


Thèmes de recherche

Characterize the NMD pathway and its deregulation by viral factors (Vincent Mocquet- projet 1)

The NMD is a quality control pathway leading to the degradation of RNA that harbor ribosomes considered by the cell to have prematurely stopped.

Read More…

Effects of DHX36 on RNA G4 quadruplexes (Stéphane Réty- projet 2)

G-quadruplexes (G4s) are four-stranded secondary structures held together by layers of four Guanines (G) interacting by non-canonical G-G base pairs. Once formed, G4s are highly stable and can act as barriers blocking replication, transcription and translation.

Read More…

Control of histone expression by INT6 and SLBP (Pierre Jalinot- projet 3)

Strenghthening the role of INT6 in genome stability, we have shown that INT6 is needed for efficient expression of the histones during the S phase of the cell cycle.

Read More…