Teams

Regulation of Genome Architecture and Dynamics of Splicing (ReGArDS) - D. Auboeuf and C. Bourgeois

Our team is interested in the regulation of alternative splicing, the main process allowing to largely increase the functional diversity of proteins (...) Read more

Chromatin Dynamics in Mitotic Chromosome Assembly - P. Bernard

The ability of the genome to adopt a dynamic 3D organisation underlies most DNA transactions. The profound reorganisation of long chromatin fibres (...) Read more

Unconventional modes of DNA maintenance and transmission - M. Delattre

We investigate unconventional modes of DNA transmission and genome regulation, exploring their evolutionary origins and consequences. Our primary (...) Read more

Systems Biology of Decision Making - O. Gandrillon

The molecular mechanisms controlling decision making at the cellular level between self-renewal and differentiation are still poorly understood. The (...) Read more

Epithelial differentiation and morphogenesis in Drosophila - M. Grammont

Posttranscriptional Regulation in Infection and Oncogenesis - Jalinot/Mocquet

Our main research interest is to decipher the molecular mechanisms underlying oncogenesis, with a particular interest in the role of genetic (...) Read more

Regulated Cell Death and Genetics of Neurodegeneration - B. Mollereau

The general goal of our lab is to understand the mechanisms of cell death, ER stress, autophagy and metabolism during development and in (...) Read more

Comparative and Integrative Genomics of Organ Development - S.Pantalacci/M. Semon

We compare genomes and transcriptomes to highlight general rules about the development and/or the evolution of organs. Read more

RNA metabolism in immunity and infection (RMI2) - E. Ricci

We are interested in post-transcriptional control mechanisms that regulate gene expression in cells of the immune system and during pathogen (...) Read more

Genetic Complexity of Living Systems - G. Yvert / F. Duveau

Our research group is interested in the fundamental genetic mechanisms underlying inter-individual phenotypic differences. We wish to better (...) Read more

Epigenetics and Zygote Formation - B. Loppin

The formation of a diploid zygote from two highly different gametes is a critical aspect of sexual reproduction in animals. Notably, the transmission (...) Read more

Physical Biology of Chromatin - D. Jost

In close connection with experimental biology, our research addresses generic or specific biological questions on chromatin and gene regulation by (...) Read more

Genome mechanics - A. Piazza

DNA is a busy molecule teeming with a zoo of static binders and molecular motors. DNA's informational, structural, and organizational properties are (...) Read more

Complexity, plasticity, and functionality of miRNAs - K. Jouravleva

We elucidate the mechanism of modular layer of post-transcriptional control formed by miRNAs, which confers developmental robustness and enables (...) Read more

Dynamics and Control of Biological Assemblies and Macromolecular Machines - J. Martin / R. Pellarin

We are a horizontal team of four researchers in computational biology. We study molecular machines and assemblies at different scales (atomistic, (...) Read more

Artificial Intelligence for Single-Cell Data Analysis (SCAI) - F. Picard

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Vivamus volutpat purus a bibendum tincidunt. Nam quam arcu, porttitor eu velit hendrerit, (...) Read more

Chromatin Architecture in Replication and Repair (CARR) - A. Delamarre

DNA double-strand breaks (DSBs) and replication stress are major threats to genome integrity that can lead to mutations and ultimately drive cancer (...) Read more

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