Accueil du site > Animations Scientifiques > Séminaires 2008 > Nuclear organization and transcription in budding yeast
Nuclear organization and transcription in budding yeast
Orateur :
Angela Taddei, Dynamique nucléaire et plasticité du génome, Institut Curie, Paris
Salle :
C023 (RDC LR6 côté CECAM)
Sujet :
Although mechanisms of gene silencing have diverged through evolution, the clustering of repetitive sequences forming repressive subcompartments enriched for specific factors, appears to be a recurrent theme. Using budding yeast as a model system, we show that this subcompartmentation of the nucleus can influence global gene expression patterns. In order to investigate the mechanisms involved in the establishment and dynamics of repeat-based nuclear subcompartments, we set up an experimental system that enables us to follow telomere clustering by live microscopy. Coupling this system with a genetic approach, we dissect the determinants of telomere foci formation and the involvement of telomere clustering in gene silencing.
Dans la même rubrique :
- Morphological analysis of slow and fast muscle cells in zebrafish embryos
- Modèles minimaux pour le mouvement collectif
- Epigenetic inheritance of chromatin states in fission yeast
- HAT MODULATORS (Activators and Inhibitors) : IMPLICATIONS IN NANOBIOTECHNOLOGY
- Exploitation de nanosondes en AFM : Dynamique d’un nanoménisque accroché à une Nano aiguille de silice et fluctuations de contact d’un Nanotube de Carbone
- Epigenetic programming of mesenchymal stem cells from adipose tissue
- The Genomic Code for Nucleosome Positioning
- Nouvel arExperiments on cytoskeletal and “Recombinase” motors
- Modelling chromosome replication in S. cerevisiae
- Chromatin remodeling during early development : which role for HIRA in Drosophila ?
- SPR characterization of proteonucleic self-assemblies
- The mechanics behind plant development : a pluridisciplinary view
- AEVOL : An Artificial Evolution model to unravel the effect of indirect selection on genomes structure
- Regulation of HIV-1 integration by chromatin structure and LEDGF/p75 protein, in vitro studies
- Biological strategies of motility
- Quantitative predictions for DNA two-dimensional display according to size and nucleotide sequence composition
- The Phosphoproteome of the Budding Yeast Centrosome
- Transferts d’énergie dans les protéines ; conception rationelle de protéines extrêmophiles
- The RAFT process, a “living” polymerization : a new step towards well-designed polymer architectures
- Chromosomal and nuclear genome architecture – an evolutionary perspective