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Accueil du site > Animations Scientifiques > Séminaires 2014 > Grégoire Malandain - Towards population studies in embryogenesis : a cell-to-cell mapping method for ascidian embryos
Grégoire Malandain - Towards population studies in embryogenesis : a cell-to-cell mapping method for ascidian embryos
Speaker : Grégoire Malandain - Morpheme team Laboratoire I3S - INRIA
When : Thursday 6th november at 11 am
Where : Salle CO23 (grande salle de réunions du CBP rez-de-chaussée LR6)
Title : Towards population studies in embryogenesis : a cell-to-cell mapping method for ascidian embryos
Nowadays, microscopy techniques allow to image temporal 3D stacks of developing organs or embryos at the cellular level and with an acquisition frequency that enables to retrieve the cell lineages. Imaging a number of organs or embryos with several conditions may help to decipher the various components that drive the development, however this requires to distinguish between the inter-individual variability and the components’ effects, enforcing the need for the comparison between individuals.
We will present a method that allows first to segment the cells from microscopy images, second to extract the symmetry plane of embryos at early stages, and third to retrieve a cell-to-cell mapping between two embryos.
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