Partenaires
Rechercher
Accueil du site > Animations Scientifiques > Séminaires 2010 > Oliver Rando — Fungal chromatin dynamics : from 15 minutes to one billion years
Oliver Rando — Fungal chromatin dynamics : from 15 minutes to one billion years
Speaker :
Oliver Rando, University of Massachusetts Medical School
When :
Monday 5 July at 17h
Where :
C023 (RDC LR6 côté Centre Blaise Pascal)
Title :
Fungal chromatin dynamics : from 15 minutes to one billion years
Abstract :
Our laboratory uses genome-wide mapping techniques to study the role of chromatin structure in transcriptional control and epigenetic inheritance in fungi. Here, I will present two ongoing efforts in our lab. In the first, we take a comparative genomics approach to nucleosome positioning, and characterize the genome-wide positions of nucleosomes in 14 fungal species spanning a billion years of evolution. In the second, we use two different pulse-chase techniques to measure the dynamics behavior of nucleosomes in budding yeast. We characterize replication-independent histone replacement, and subsequently follow how nucleosomes behave during genomic replication. Our results have interesting implications for the evolution of gene regulation, the role of sequence in nucleosome positioning, and the plausibility of chromatin as a carrier of epigenetic information.
Dans la même rubrique :
- Olivier Gandrillon — A system’s biology approach to understand stochasticity in gene expression
- François Graner — Dynamique des matériaux cellulaires : l’exemple des mousses
- Eric Clément —
- Jacques Pecreaux — Doing the spindle rock. Mitotic spindle motion in C elegans one-cell embryo.
- Arach Goldar — Measuring the time dependent rate of replication origin activation in a single {Saccharomyces cerevisiae} cell by using population dynamics
- Gijsje Koenderink — Active self-organization of the actin cytoskeleton driven by molecular motors
- M. Carmen Romano — Traffic dynamics of translation : modelling the synthesis of proteins
- Antonin Morillon — Regulatory non coding (nc)RNA and epigenetic in yeast
- Michael Lässig — Molecular evolution in fitness landscapes and seascapes
- Ala Trusina — Defining Network Topologies that Can Achieve Biochemical Adaptation
- George Reid —
- Malcolm Buckle — Etude cinétique et dynamique des complexes macromoléculaires impliquées dans la régulation de l’expression génique par la résonance des plasmons de surface
- Anne-Marie Tassin — Procentriole assembly revealed by cryo-electron tomography
- André Estévez-Torres — Synthetic epigenetics : Sequence-independent photocontrol of gene expression in vitro
- Olivier Cuvier — Deciphering the Discrete Stages of Insulator-encoded Nucleosome-Positioning : The Road towards Transcriptional Competence
- Nick Gilbert — Effect of DNA supercoiling on chromatin structures
- Aurélien Rappailles — Genome wide study of Human DNA replication
- Christophe Lavelle — Chromatin : the DNA manager (and vice versa)
- Michelle D. Wang — DNA Accessibility in Nucleosomes
- Shixin Ye — Application of site-directed mutagenesis with unnatural amino acids in studies of G protein-coupled receptors
