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Accueil du site > Animations Scientifiques > Séminaires 2013 > Franck Riquet - Optimized and reliable genetically encoded molecular tools for the visualization of cellular process dynamics.
Franck Riquet - Optimized and reliable genetically encoded molecular tools for the visualization of cellular process dynamics.
Speaker : Franck Riquet, Associate Professor of cell biology, EA 4479, Lille1 University, joint with BCF team, IRI CNRS USR 3078, Lille, France
When : thursday 13 rd june at 11 am
Where : Salle CO23 (grande salle de réunions du CBP rez-de-chaussée LR6)
Title :Optimized and reliable genetically encoded molecular tools for the visualization of cellular process dynamics.
Biological processes are intrinsically dynamic. Although traditional methods provide valuable insights for the understanding of many biological phenomenon, the possibility nowadays to measure, quantify and localize protein within a cell, a tissue, an embryo has revolutionized our train of thoughts and has encourage scientists to develop molecular tools for the assessment of protein localization and activities as well as protein complexes dynamics within their physiological context. These ongoing efforts are resting on the emergence of biophotonics and the everlasting improvement of fluorescence probes, allowing precise and reliable measurements of cellular functions dynamics from cellular models to model organisms. The march of the “in vivo biochemistry” has begun, already yielding breathtaking results. To exemplify our involvement on such a research path, I will take you on a journey throughout a series of collaborative projects, developed over the years, aiming at bettering our understanding of cellular processes (cell proliferation, cell death and cell adhesion). Always center around the biological question at stakes, we have developed reliable and optimized genetically encoded molecular reporters as well as sophisticated fluorescent imaging approaches in order to assess protein dynamics in living cells and tissues.
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