Laboratoire de Biologie et Modélisation de la Cellule - UMR 5239 - Inserm 1293
The LBMC is an experimental biology laboratory hosted at ENS de Lyon in a multidisciplinary scientific environment. The laboratory's main subject of study is the cell, which is the most fundamental unit of life.
The 15 research teams aim at integrating diverse aspects of cell life such as proliferation, differentation, and interaction with cellular environment in a normal or pathogenic context. The fundamental research pursued in the laboratory relies on expertise in cellular and molecular biology and integrates interdisciplinary approaches in (bio)computing, (bio)physics and (bio)mathematics.
More details here.
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- Last publications
- 2024 Elife Yeast cell responses and survival during periodic (...) N (...)
- 2024 J Chem Inf Model AlphaFold2 Predicts Whether Proteins Interact (...)
- 2024 Cell Rep RNAP II antagonizes mitotic chromatin folding and (...) C (...)
- 2023 Proteomics Discriminating physiological from (...)
- 2023 Nature Communications Expulsion mechanism of the (...)
- 2023 Structure Transmembrane dimers of type 1 receptors sample (...)
- 2023 Biophysical Journal An implementation of the Martini coarse-grained (...)
- 2022 Anal Chem Mono- and Intralink Filter (Mi-Filter) To Reduce (...) C (...)
- 2023 J Mol Biol Coevolution-Guided Mapping of the Type VI (...) T (...)
- 2023 PLoS Pathog Acinetobacter type VI secretion system comprises (...) A (...)
- 2024 Nat Commun Assembly of a unique membrane complex in type VI (...) T (...)
- 2023 eLife Carm1-arginine methylation of the transcription (...) H (...)
- News
- Teams
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Dynamics and Control of Biological Assemblies and Macromolecular MachinesWe are a horizontal team of four researchers in computational biology. We study molecular machines (...) Read more
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Complexity, plasticity, and functionality of miRNAsWe elucidate the mechanism of modular layer of post-transcriptional control formed by miRNAs, which (...) Read more
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Genome mechanicsDNA is a busy molecule teeming with a zoo of static binders and molecular motors. DNA's (...) Read more
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Physical Biology of ChromatinIn close connection with experimental biology, our research addresses generic or specific (...) Read more
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Epigenetics and Zygote FormationThe formation of a diploid zygote from two highly different gametes is a critical aspect of sexual (...) Read more
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RNA metabolism in immunity and infection (RMI2)We are interested in post-transcriptional control mechanisms that regulate gene expression in cells (...) Read more
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Genetic Complexity of Living SystemsOur research group is interested in the fundamental genetic mechanisms underlying inter-individual (...) Read more
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Epigenetic regulation of cell identity and environmental stress responsesWe are interested in understanding the role of conserved chromatin marks in the maintenance of (...) Read more
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Evolutionary Cell Biology in NematodesWe investigate unconventional modes of DNA transmission and genome regulation, exploring their (...) Read more
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Regulated Cell Death and Genetics of NeurodegenerationThe general goal of our lab is to understand the mechanisms of cell death, ER stress, autophagy and (...) Read more
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Quantitative regulatory genomicsWhy are individuals different? We address this fundamental question by studying both genetic and (...) Read more
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Regulation of Genome Architecture and Dynamics of Splicing (ReGArDS)Our team is interested in the regulation of alternative splicing, the main process allowing to (...) Read more
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Comparative and Integrative Genomics of Organ DevelopmentWe compare genomes and transcriptomes to highlight general rules about the development and/or the (...) Read more
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Posttranscriptional Regulation in Infection and OncogenesisOur main research interest is to decipher the molecular mechanisms underlying oncogenesis, with a (...) Read more
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Epithelial differentiation and morphogenesis in DrosophilaRead more
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Systems Biology of Decision MakingThe molecular mechanisms controlling decision making at the cellular level between self-renewal and (...) Read more
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Chromatin Dynamics in Mitotic Chromosome AssemblyThe ability of the genome to adopt a dynamic 3D organisation underlies most DNA transactions. The (...) Read more
- Interdisciplinarity
- Dissemination of knowledge
- Seminars
- Apr 26, 2024 Understanding how the DNA-loop-extruding protein complex Condensin folds a chromatinized genome into mitotic chromosomes
- May 03, 2024 Racing the 3' end: tracking the speed, accuracy, and coordination of mRNA biogenesis
- May 06, 2024 Clément Carré (Sorbonne Université, Paris) / Hervé Seitz (Institut de Génétique Humaine, Montpellier) / Sébastien Pfeffer (Université de Strasbourg)
- May 17, 2024 Phylogenetic identification of sites and genes associated to discrete and continuous phenotypes
- Upcoming thesis defenses
- May 07, 2024
HDR Defense - Karina JOURAVLEVA
K. Jouravleva, Amphi B
- Job Offers
- Feb 01, 2024
- Dec 13, 2023
- Nov 23, 2023