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Laboratoire de Biologie et Modélisation de la Cellule - UMR 5239 - Inserm 1293

The LBMC is an experimental biology laboratory hosted at ENS de Lyon in a multidisciplinary scientific environment. The laboratory's main subject of study is the cell, which is the most fundamental unit of life.

The 15 research teams aim at integrating diverse aspects of cell life such as proliferation, differentation, and interaction with cellular environment in a normal or pathogenic context. The fundamental research pursued in the laboratory relies on expertise in cellular and molecular biology and integrates interdisciplinary approaches in (bio)computing, (bio)physics and (bio)mathematics.

More details here.

Follow us on Twitter @Lyon_LBMC

Last publications
2023 Emelyanov A & al, Journal of Biological Chemistry APOLLO, a testis-specific Drosophila ortholog of (...)
2023 Arbona J & al, PLoS Comput Biol Neural network and kinetic modelling of human (...) I (...)
2023 Tortora M & al, Proc Natl Acad Sci U S A HP1-driven phase separation recapitulates the (...) T (...)
2023 Orsi G & al, Nat Commun Biophysical ordering transitions underlie genome (...) S (...)
2023 Mollereau B & al, Autophagy A burning question from the first international (...) B (...)
2022 Ichim G & al, Biomolecules Keeping Cell Death Alive: An Introduction into (...) S (...)
2023 Reitz D & al, Genes and Development Delineation of two multi-invasion-induced (...) P (...)
2023 Orsi G & al, Nature Communications Biophysical ordering transitions underlie genome (...) A (...)
2023 Vedanayagam J & al, PLOS Biology Essential and recurrent roles for hairpin RNAs in (...) A (...)
2023 Tortora M & Jost D, Macromolecules Orientational Wetting and Topological Transitions (...)
2023 Abdulla A & al, Curr Opin Genet Dev 4D epigenomics: deciphering the coupling between (...) R (...)
2023 Caron M & al, bioRxiv SIN3 acts in distinct complexes to regulate the (...) T (...)
News
Teams
Genome mechanics
Homologous recombination is a universal DNA break repair pathway involved in a variety of (...) Read more
Physical Biology of Chromatin
In close connection with experimental biology, our research addresses generic or specific (...) Read more
Epigenetics and Zygote Formation
The formation of a diploid zygote from two highly different gametes is a critical aspect of sexual (...) Read more
RNA metabolism in immunity and infection (RMI2)
We are interested in post-transcriptional control mechanisms that regulate gene expression in cells (...) Read more
Genetic Complexity of Living Systems
Our research group is interested in the fundamental genetic mechanisms underlying inter-individual (...) Read more
Epigenetic regulation of cell identity and environmental stress responses
We are interested in understanding the role of conserved chromatin marks in the maintenance of (...) Read more
Evolutionary Cell Biology in Nematodes
We compare basic cellular functions between closely related species. We ask to what extent the (...) Read more
Regulated Cell Death and Genetics of Neurodegeneration
The general goal of our lab is to understand the mechanisms of cell death, ER stress, autophagy and (...) Read more
Quantitative regulatory genomics
Why are individuals different? We address this fundamental question by studying both genetic and (...) Read more
Regulation of Genome Architecture and Dynamics of Splicing (ReGArDS)
Our team is interested in the regulation of alternative splicing, the main process allowing to (...) Read more
Comparative and Integrative Genomics of Organ Development
We compare genomes and transcriptomes to highlight general rules about the development and/or the (...) Read more
Posttranscriptional Regulation in Infection and Oncogenesis
Our main research interest is to decipher the molecular mechanisms underlying oncogenesis, with a (...) Read more
Epithelial differentiation and morphogenesis in Drosophila
Read more
Systems Biology of Decision Making
The molecular mechanisms controlling decision making at the cellular level between self-renewal and (...) Read more
Chromatin Dynamics in Mitotic Chromosome Assembly
The ability of the genome to adopt a dynamic 3D organisation underlies most DNA transactions. The (...) Read more
 
 
Seminars
Sep 29, 2023
Aurèle PIAZZA & Agnès DUMONT
Development of ssDNA-specific Hi-C protocol reveals a controlled expansion of homology search during DNA break repair by homologous recombination
Oct 06, 2023
Antoine GUICHET, Institut Jacques Monod - Paris
Coordination of different microtubule networks to position a nucleus asymmetrically.
Oct 20, 2023
Biocomputing Hub
Oct 27, 2023
Nitin Phadnis, University of Utah, Salt Lake City, USA
What else ?
Salut les scientifiques
Recent publication - 11/2022
Pint of Science Nena Martin
Nena Martin a rejoint l’équipe Lyonnaise de Pint of Science. Nous sommes allées l’interviewer (...)
L'image du mois