Laboratoire de Biologie et Modélisation de la Cellule - UMR 5239 - Inserm 1293
The LBMC is an experimental biology laboratory hosted at ENS de Lyon in a multidisciplinary scientific environment. The laboratory's main subject of study is the cell, which is the most fundamental unit of life.
The 15 research teams aim at integrating diverse aspects of cell life such as proliferation, differentation, and interaction with cellular environment in a normal or pathogenic context. The fundamental research pursued in the laboratory relies on expertise in cellular and molecular biology and integrates interdisciplinary approaches in (bio)computing, (bio)physics and (bio)mathematics.
More details here.
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- Last publications
- 2022 PLoS Biol Global genome decompaction leads to stochastic (...) W (...)
- 2022 Nucleic Acids Res Painters in chromatin: a unified quantitative (...) I (...)
- 2022 PLoS Comput Biol Dynamical modeling of the H3K27 epigenetic (...) T (...)
- 2022 J Vis Exp Detection of Homologous Recombination (...) D (...)
- 2022 Mol Oncol Altered splicing of ATG16-L1 mediates acquired (...) D (...)
- 2022 Nucleic Acids Res RNA helicase-dependent gene looping impacts (...) D (...)
- 2022 Nature Methods Real age prediction from the transcriptome with (...) T (...)
- 2022 Nat Commun Myotonic dystrophy RNA toxicity alters (...) B (...)
- 2022 Methods Mol Biol DNA:RNA Immunoprecipitation from S. pombe Cells (...) B (...)
- 2022 EMBO Rep Structural mechanism underpinning Thermus oshimai (...) G (...)
- 2022 Biomolecules A Perspective for Ménière's Disease: In Silico (...) M (...)
- 2022 Nucleic Acids Res 3DGenBench: a web-server to benchmark (...) M (...)
- News
- Teams
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Genome mechanicsHomologous recombination is a universal DNA break repair pathway involved in a variety of (...) Read more
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Physical Biology of ChromatinIn close connection with experimental biology, our research addresses generic or specific (...) Read more
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Epigenetics and Zygote FormationThe formation of a diploid zygote from two highly different gametes is a critical aspect of sexual (...) Read more
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RNA metabolism in immunity and infection (RMI2)We are interested in post-transcriptional control mechanisms that regulate gene expression in cells (...) Read more
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Genetic Complexity of Living SystemsOur research group is interested in the fundamental genetic mechanisms underlying inter-individual (...) Read more
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Epigenetic regulation of cell identity and environmental stress responsesWe are interested in understanding the role of conserved chromatin marks in the maintenance of (...) Read more
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Evolutionary Cell Biology in NematodesWe compare basic cellular functions between closely related species. We ask to what extent the (...) Read more
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Regulated Cell Death and Genetics of NeurodegenerationThe general goal of our lab is to understand the mechanisms of cell death, ER stress, autophagy and (...) Read more
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Quantitative regulatory genomicsWhy are individuals different? We address this fundamental question by studying both genetic and (...) Read more
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Regulation of Genome Architecture and Dynamics of Splicing (ReGArDS)Our team is interested in the regulation of alternative splicing, the main process allowing to (...) Read more
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Comparative and Integrative Genomics of Organ DevelopmentWe compare genomes and transcriptomes to highlight general rules about the development and/or the (...) Read more
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Posttranscriptional Regulation in Infection and OncogenesisOur main research interest is to decipher the molecular mechanisms underlying oncogenesis, with a (...) Read more
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Epithelial differentiation and morphogenesis in DrosophilaRead more
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Systems Biology of Decision MakingThe molecular mechanisms controlling decision making at the cellular level between self-renewal and (...) Read more
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Chromatin Dynamics in Mitotic Chromosome AssemblyThe ability of the genome to adopt a dynamic 3D organisation underlies most DNA transactions. The (...) Read more
- Interdisciplinarity
- Dissemination of knowledge
- Seminars
- Feb 03, 2023 Using the circadian clock to uncover mechanisms and functions of post-transcriptional gene expression regulation
- Feb 10, 2023 Unexpected forces shaping sperm chromatin evolution
- Feb 17, 2023 Adaptive intergenerational memory of pheromone perception in C. elegans
- Feb 21, 2023 Mechanism and regulation of DNA repair: RAD52 and BRCA2 regulate pathway choice in double-stranded DNA break repair
- Past thesis defenses
- Dec 19, 2022
Fabien AUBE - Eq Auboeuf-Bourgeois
Equipe Auboeuf-Bourgeois, Salle des thèses
- Dec 16, 2022
Léa PROCHASSON - Eq Bernard
Amphi B - Equipe Bernard
- What else ?
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Nena Martin a rejoint l’équipe Lyonnaise de Pint of Science. Nous sommes allées l’interviewer (...)
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