After my masters in Chemistry from Indian Institute of Technology (IIT), Mumbai (India) in 2006, I joined the Swiss Federal Institute (EPFL) in Lausanne (Switzerland) to complete a Phd in developing new NMR methods using Long-Lived States for studying slow dynamic processes of biomolecules. After finishing my Phd in 2010, I joined a CNRS laboratory (CNRS UMR 8576) in Lille (France) as a post doc, where I worked upon studying structure and dynamics by NMR of a new class of therapeutics, alphabodies, that has entered into pre clinical phase of drug development.
Presently, I am working as a post doc at AstraZeneca R&D Mölndal (Sweden) under the framework of pNMR network with the project entitled “Structure determination of ligands bound to paramagnetically tagged target proteins of pharmaceutical interest”. This complementary approach to X-ray crystallography could be of of tremendous value as it would enable more efficient synthetic chemistry efforts in drug discovery at AstraZeneca.
| Home Country | India |
| Project Topic | Structure determination of ligands bound to paramagnetically tagged target proteins of pharmaceutical interest |
| Project Description | |
| Project Home | AstraZeneca AB |
| Supervisor | Tomas Åkerud |
| Starting Date | March 2014 |
| Publications | |
| Meetings | EMBO Training Course, and SU Applied Training Course, July 2014, Florence, Italy Title: Solution and Solid-state NMR of Paramagnetic Molecules Role: participant SU Applied Training Course, July 2014, Florence, Italy Title: NMR Relaxation Theory Role: participant LEIDEN and ZoBIO Applied Training Course, August 2014, Leiden, the Netherlands Title: Paramagnetic tagging for drug research Role: participant pNMR Workshop, September 2014, Cambridge, UK Multidisciplinary Workshop #2 Title: “New Developments in Experimental and Theoretical Techniques for the Study of Paramagnetic Inorganic Materials”/span> Role: participant pNMR Mid-Term Review Meeting, September 2014, Cambridge, UK Role: participant pNMR Workshop 3, Prague, CZ Title: pNMR : from rags to riches, Challenges and potentials of NMR on paramagnetic molecules, Role: speaker |
| Secondments | 19th May- 22nd July 2014 : GIOTTO, Italy; 18th August -12th September, 2014. Leiden, Netherlands; July-August 2015 : Leiden |