All year long, students and staff can participate to several cultural activities as well as benefit from the school's facilities such as the theater or the gallery and other exhibition rooms.

The Science Festival (Fête de la science) is the opportunity to discover all the sciences: biology, physics, chemistry, mathematics, but also human and social sciences.

For the annual "Rendez-vous aux jardins" (Garden rendez-vous), ENS de Lyon opens its gardens, designed by Gilles Clément, to the general public.

Each year, the Université de Lyon Foundation and the ENS de Lyon host a new edition of the "Economy Days" (Journées de l’Economie), a three-day round of conferences that aim to make the economy an intelligible and engaging topic for debate.