The LBMC aims to characterise the molecular bases underlying the organisation and functioning of cellular processes in normal and pathological conditions. The laboratory develops genetic and quantitative analyses of biological systems, systems biology and modelling approaches.
Teams strive to integrate different aspects of cellular life: cell division, architecture, proliferation and differentiation, tissue integration, regulation of gene expression, epigenetics, structure and interaction of biomolecules. A variety of experimental models are used in our research, including budding and fission yeasts, Drosophila, C. elegans, rodents, chicken as well as murine and human cells.
- Quantitative approaches to genome dynamics and expression
- Cellular and molecular pathological processes
- Systems biology of signaling and developmental cellular processes