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Plan du site
Rubrique : Présentation
Articles et sous-rubriques :
Rubrique : Contact - Venir au Laboratoire
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Rubrique : L’infrastructure
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Rubrique : Thèmes de recherche
Articles et sous-rubriques :
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Biophysics and development. Project Leader : Arezki Boudaoud.
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Previously Hosted Projects
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Assembly of chromatin and ribosome biogenesis. Project leader : Philippe Bouvet.
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Polymers for Fluorescence Imaging in Infectiology. Project leader : Marie-Thérèse Charreyre.
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Chromatin and Retroviral Integration. Project leader : Marc Lavigne.
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Dynamics of swimming bacteria in the vicinity of surfaces. Project leader : Laurence Lemelle.
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Physics to study the living. Project leader : Christophe Place.
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Epithelia. Group leader : Muriel Grammont
Rubrique : Organigramme
Articles et sous-rubriques :
Rubrique : Emplois et Stages
Articles et sous-rubriques :
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Candidature Spontannée
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Postes à pourvoir
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Stages
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Sujets de Thèses
- PhD Project : « Modélisation biophysique de la répression heterochromatinienne »
- PhD Project : « Building mechanical models of morphogenesis in plants »
- PhD Project : « Multi-scale modeling of the spatio-temporal programme of replication in the chromatin context »
- PhD Project : « The role of a ‘mechanical identity’ in growth and morphogenesis in Arabidopsis »
- PhD Project : « Unraveling the physical basis of morphogenesis in plants through a three-dimensional map of mechanical properties »
- PhD Project : MECHANICAL RESPONSE OF CELLULAR SYSTEMS : Do cells have a sense of touch ?
Rubrique : Animations Scientifiques
Articles et sous-rubriques :
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Séminaires 2010
- Ala Trusina — Defining Network Topologies that Can Achieve Biochemical Adaptation
- André Estévez-Torres — Synthetic epigenetics : Sequence-independent photocontrol of gene expression in vitro
- Andrew Travers — DNA structure and topology - determinants of gene expression and chromatin organisation
- Anne-Marie Tassin — Procentriole assembly revealed by cryo-electron tomography
- Antonin Morillon — Regulatory non coding (nc)RNA and epigenetic in yeast
- Arach Goldar — Measuring the time dependent rate of replication origin activation in a single {Saccharomyces cerevisiae} cell by using population dynamics
- Aurélien Rappailles — Genome wide study of Human DNA replication
- Christophe Lavelle — Chromatin : the DNA manager (and vice versa)
- Cyril Favard — FCS diffusion laws on two-phases lipid membranes : experimental and Monte-Carlo simulations determination of domain mean size
- Eric Clément —
- François Graner — Dynamique des matériaux cellulaires : l’exemple des mousses
- George Reid —
- Gijsje Koenderink — Active self-organization of the actin cytoskeleton driven by molecular motors
- Jacques Pecreaux — Doing the spindle rock. Mitotic spindle motion in C elegans one-cell embryo.
- M. Carmen Romano — Traffic dynamics of translation : modelling the synthesis of proteins
- Malcolm Buckle — Etude cinétique et dynamique des complexes macromoléculaires impliquées dans la régulation de l’expression génique par la résonance des plasmons de surface
- Marc Ruff — Structural and functional role of ini1, a cellular cofactor of hiv-1 integrase in the early step of hiv infection
- Maria-Elena Torres-Padilla — Epigenetic regulation of mammalian development : a unique heterochromatin environment
- Michael Lässig — Molecular evolution in fitness landscapes and seascapes
- Michelle D. Wang — DNA Accessibility in Nucleosomes
- Nick Gilbert — Effect of DNA supercoiling on chromatin structures
- Oliver Rando — Fungal chromatin dynamics : from 15 minutes to one billion years
- Olivier Cuvier — Deciphering the Discrete Stages of Insulator-encoded Nucleosome-Positioning : The Road towards Transcriptional Competence
- Olivier Gandrillon — A system’s biology approach to understand stochasticity in gene expression
- Olivier Gascuel —
- Sébastien Perrier — Nanostructured Materials from Natural/Synthetic Polymer Conjugates
- Shixin Ye — Application of site-directed mutagenesis with unnatural amino acids in studies of G protein-coupled receptors
- Youlian Goulev — Identification du lien entre le signal antiprolifératif Hippo et l’expression génique chez Drosophila melanogaster
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Séminaires 2009
- Alain Nicolas — Minisatellite instability and G-quadruplexes
- Alexandre Dazzi — Spectromicroscopie infrarouge sub-longueur d’onde induite par effet photothermique (PTIR)
- Andrew Travers — Nucleosome positioning and chromatin topology
- Arnaud Favier — Macromolecular design using controlled radical polymerization. Example of biomedical applications
- Atef Asnacios — Mécano-sensibilité à l’échelle d’une cellule vivante : un peu de physique expérimentale
- Biophotonics in living cells
- Christophe Thiriet — Fonctions régulatrices des histones dans la réplication, de la déstabilisation de la chromatine à son assemblage
- Elise Praly — Etude comparée des activités de deux facteurs de remodelage de la chromatine (RSC et yISW1a), à l’échelle de la molécule unique.
- Françoise Livolant — Ejection de l’ADN du bactériophage vu par cryomicroscopie électronique
- Hervé Rouault — Identication and characterization of cis-regulatory elements for co-regulated genes
- Internal Seminar — Gilles Charvin — Monitoring yeast replicative aging at the single-cell level
- Intra- and inter-nucleosome interactions of the core histone tail domains
- Jiemin Wong — Identification and characterization of histone code effectors
- Nicolas Biais — Les superpouvoirs d’un microhéros
- Polymerization and mechanochemical action of dynamin
- Raymond Goldstein — Flagellar Synchronization, Eukaryotic Random Walks, and the Fidelity of Multicellular Phototaxis
- Séminaire Interne — Cédric Vaillant
- Tapas K. Kundu — Acetylation of Histones and Histone Chaperones in Cancer Manifestation : Implications in Therapeutics
- Teresa Teixeira — Séminaire Interne
- Un nouveau lien entre la méthylation de l’histone H3 et les sites de recombinaison le long des chromosomes méiotiques
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Séminaires 2008
- 4C technology : uncovering the multi-dimensional organisation of the genome
- AEVOL : An Artificial Evolution model to unravel the effect of indirect selection on genomes structure
- Assemblages photo- stimulables de macromolécules amphiphiles modifiées azobenzene.
- Biological strategies of motility
- Chromatin remodeling during early development : which role for HIRA in Drosophila ?
- Chromosomal and nuclear genome architecture – an evolutionary perspective
- E. coli et l’oxygène, étude d’une transition de phase
- Epigenetic inheritance of chromatin states in fission yeast
- Epigenetic programming of mesenchymal stem cells from adipose tissue
- Exploitation de nanosondes en AFM : Dynamique d’un nanoménisque accroché à une Nano aiguille de silice et fluctuations de contact d’un Nanotube de Carbone
- Formes de croissance
- HAT MODULATORS (Activators and Inhibitors) : IMPLICATIONS IN NANOBIOTECHNOLOGY
- Maintenance of genome integrity during DNA replication in yeast and in human cells
- Modèles minimaux pour le mouvement collectif
- Modelling chromosome replication in S. cerevisiae
- Morphological analysis of slow and fast muscle cells in zebrafish embryos
- Nouvel arExperiments on cytoskeletal and “Recombinase” motors
- Nuclear organization and transcription in budding yeast
- Observation électrochimique d’événements uniques en biologie
- Quantitative predictions for DNA two-dimensional display according to size and nucleotide sequence composition
- Regulation of HIV-1 integration by chromatin structure and LEDGF/p75 protein, in vitro studies
- Sensory logic of odor perception in Drosophila larvae
- SPR characterization of proteonucleic self-assemblies
- The Genomic Code for Nucleosome Positioning
- The mechanics behind plant development : a pluridisciplinary view
- The Phosphoproteome of the Budding Yeast Centrosome
- The RAFT process, a “living” polymerization : a new step towards well-designed polymer architectures
- Transferts d’énergie dans les protéines ; conception rationelle de protéines extrêmophiles
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Séminaires 2007
- About multicenter redox enzymes, how they work, and how to study them using direct electrochemistry - Sur le fonctionnement des enzymes rédox multicentres et leur étude par électrochimie directe
- Chromatin dynamics in interphase
- Conservative behavior of the biological complex system [Telomeres-Telomerase-Prolifération]
- Cytoskeleton dynamics involved in cell morphology control and multicellular stability
- Discrete breathers in nonlinear network models of proteins
- Distinct roles of core histones, histone variants and linker histones in chromatin function
- DNA : More than just a ladder
- Electron-donor modified nanoparticles for selected cell labeling and photodynamic therapy
- Exploration électrochimique de la dynamique de brins courts d’ADN ancrés sur une surface
- Function of C. elegans HP1 proteins in post-embryonic development
- Histone H1 is a architectural molecule required for chromatin compaction, and is redundant for gene repression
- Human monoclonal antibodies against viruses and cancer
- Linking molecular mechanisms to the organism’s physiology using transcriptomics
- Models for the interaction between antibiotic peptides and lipid bilayers - Modèles pour l’interaction entre des peptides antibiotiques et des bicouches lipidiques
- Molecular mechanisms of gene transcription and DNA repair in living cells
- On the role of the retroviral Gag protein and the RNA in virus assembly
- Protéines : mécanique et fonction
- Que cache la iCDR ? (interphase Centromere Damage Response)
- Sequence rules for nucleosome positioning and chromatin architecture
- Small Molecule Modulators of Chromatin Modifying Enzymes : To Probe Eukaryotic Transcription and To Target Diseases
- Soutenance d’HDR:Les modes normaux de basse fréquence des protéines
- Structural insights into base damage recognition and removal by the Fpg DNA glycosylase
- The Hitchhikers Guide Through the Cytoplasm
- The nucleosome : A transparent, slippery, sticky and yet stable DNA-protein complex
- Transcription by yeast RNA polymerase III and Chromatin Remodeling
- Vésicules biomimétiques à base de PIP2 pour étudier des interactions protéines membranes : application à une protéine de la famille des ERM (ezrine, radixine, moésine).
- What determines the size of virus ?
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Doctorat 2008 —
- Antoine Baker — Le programme spatio-temporel de réplication et son impact sur l’asymétrie de composition dans le génome humain
- Dynamique à l’équilibre et hors équilibre de la chromatine visualisée par Microscopie à Force Atomique : effet des variants d’histone et des facteurs de remodelage
- Effets de séquence sur les propriétés thermodynamiques de brins d’ADN : de la théorie à l’expérience
- Guillaume Chevereau — Thermodynamique du positionnement des nucléosomes
- La réparation par excision de base d’une lésion oxydative sur des matrices nucléosomales
- Lamia Zaghloul — Transcriptional activity, chromatin state and replication timing in domains of compositional skew in the human genome
- Thibault Roland — Localized Surface Plasmon Imaging : a non intrusive optical tool to cover nanometer to micrometer scales in biological systems
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Habilitations à Diriger les Recherches
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Documents Intervenants
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Séminaires 2014
- Anne-Françoise Mingotaud - Polymeric self-assemblies for photodynamic therapy
- Antoine Delon - Fluorescence fluctuation microscopy or how to measure concentration and mobility of molecules for cellular biology.
- Florence Ruggiero - Unconventional collagens of basement membranes : lessons from morpholino-based screening in zebrafish
- Giovanni Cappello - Mechanics and Tumor growth
- Grégoire Malandain - Towards population studies in embryogenesis : a cell-to-cell mapping method for ascidian embryos
- Iva Ugrinova - HMGB1 AS AN ARCHITECTURAL CHROMATIN PROTEIN AND EXTRACELLULAR SIGNALLING MOLECULE
- Jérémy Gruel - Differentiation control in the Shoot Apical Meristem, an inside out model
- Magali Suzanne - Développement de la patte de la drosophile. Implication de la mort cellulaire. Modelisation du processus.
- Marc Lefranc - Modélisation mathématique des horloges circadiennes : d’une algue microscopique aux mammifères
- Martial Balland - Cell dipole behavior revealed by ECM geometry
- Olivier Espeli - Regulation of chromosome segregation in bacteria
- Romain Koszul - Insights into the diversity of microorganisms chromosome organization
- Sebastian Schornack - How to be a good host – microbial and host strategies to control colonisation
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Séminaires 2013
- Bertrand Fourcade - From integrin activation to reaction-diffusion models : How podosomes organizations can be described as local self-sustained excitation waves of localized PdtIns(4,5)2 synthesis.
- Boudewijn van der Sanden - Microscopie intravitale pour les neurosciences, un monde interdisciplinaire pour explorer les cellules du système nerveux central dans l’animal entier
- Chistophe Zimmer - Microbiology through a computational lens : imaging & modeling approaches and applications to yeast nuclear architectureand HIV
- Christian Bergaud - Nanotechnology and Nanomaterials : promises for improved functional devices with applications in chemistry and biology.
- Christophe Godin - Modeling the mechanical regulation of morphogenesis in plants
- Daniel Riveline - Examples of phenomena in cell physics : cell motility and cell division
- Davide Normanno - Target search mechanisms of DNA-binding proteins : How to be at the right place at the right time ?
- Edouard Bertrand - RNA polymerase II : how cells assemble it and get genes transcribed
- Edwige Moyroud - Under the rainbow : how plants build nanophotonic structures to manipulate the light and attract pollinators.
- Francesca Di Nunzio - HIV-1 docking at the nuclear pore, nuclear import and integration, concerted steps of HIV-1 infection
- Franck Riquet - Optimized and reliable genetically encoded molecular tools for the visualization of cellular process dynamics.
- Jean-Baptiste Sibarita - Resolving molecular organization and dynamics of post-synaptic molecules using localization-based super-resolution microscopy
- Karine Monier / Xavier Gaume : Super-resolution microscopy
- Laurent Blanchoin - Directed actin self assembly and contractility
- Laurent Cognet - From long-term single molecule tracking to super-resolution imaging of complex molecular organizations in living cells.
- Manouk Abkarian - Elastic prison break of malaria parasites : how to use the physics of the gift ribbon
- Marcus Buschbeck - MacroH2A contributes to the establishment and stabilization of differentiated epigenomes
- Massimo Vergassola - Finding the needle in a biological haystack
- Pierre-Alix dancer - Descriptif du Fluobeam et ses applications
- Sylvain Gabriele - Adhesion, force and form : how cell mechanics control cellular functions ?
- Thomas Risler - Mechanics and stability of healthy and cancerous tissues
- Vincent Calvez - Un modèle biomécanique pour l’interdigitation des sutures crâniennes.
- Virgile Adam - Phototransformable fluorescent proteins : new tools for cell biology
- Winfried Weissenhorn - Structural basis of ESCRT-driven release of enveloped viruses
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Séminaires 2012
- Annie Viallat - Dynamics of blood cells in the microcirculation
- Ben Ovryn — Modeling and ultra-high resolution optical microscopy of the formation of nouveau adhesions
- Claudia Fritz - Évaluation de la qualité du violon : cohérence des jugements et préférences des musiciens
- David M. Gilbert — Developmental Control of Replication Timing and Chromosome Architecture
- Dominique Ploton - Targeted quantification of water and ions using correlative Cryo-Fluorescence and Analytical Scanning Transmission Electron Microscopy.
- Jean-Christophe Andrau — CpG islands is the primary code of chromatin opening at mammalian promoters
- Jean-Louis Mergny — Les quadruplexes sont partout !
- Jos Käfer — Gender in plants : genomic consequences of dioecy in Silene
- José Paulo Farinha - DNA Hybridization in Smart Polymer Nanoparticles
- Martin Castenovo — Physical properties of retroviruses
- Marylin Vantard — Organization of microtubules in acentriolar cells : chaos or self-order ?
- Mathias Fink — Imager les propriétés viscoélastiques des tissus
- Mathieu Boulard - TRIM28 Represses Methylated Promoters and Enforces Monoallelic Expression of Imprinted Genes
- Matthieu Piel — Cell migration under confinement : from physical constraints to biological functions
- Muriel Grammont - Bridging the gaps between signalling, mechanical forces and morphogenesis in the Drosophila egg chamber
- Nicolas Minc - "THE INS AND OUTS OF CELLULAR MORPHOGENESIS"
- Olivier Destaing — Moving from genetic to optogenetics : a new way to understand the complex dynamics of invadosomes
- Patricia Rousselle — Toward understanding of syndecan-1 function in cell adhesion to laminin
- Stéphane Vincent - Bridging the gap between signalling and morphogenesis in the Drosophila embryo
- Thomas Gibaud — Reconfigurable self-assembly through chiral control of interfacial tension
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Séminaires 2011
- André Verdel — Connexions entre ARN interférence (RNAi) et chromatine chez S. pombe
- Aurélien Bancaud — Micro et nanosystèmes fluidique pour l’étude des chromosomes
- Bertrand Fourcade — Activation et agrégation de récepteurs d’adhésion : approche physique
- Bertrand Mollereau — Modeling Neurodegenerative diseases in Drosophila
- Charles Auffray, Laurent Nottale — Systems Biology and Scale Relativity
- Christian Jaulin — Regulation of sister chromatid cohesion by histone modifications at centromeres
- Claire Francastel — Hypométhylation, transcription des régions centromériques et pathologies
- Daniel Needleman — Physical Aspects of Spindle Assembly
- Didier Boturyn — Conception de Vecteurs Peptidiques : Applications Thérapeutiques et Diagnostiques
- Emmanuel Caussinus — Intermediate Physics for Drosophilist
- Emmanuel Farge — Mechano-genetic coupling in embryogenesis : anterior mi-dgut differentiation and mesoderm invagination
- François Parcy — Can genomic sequences help us to understand flower evolution ?
- Francis Corson — Geometry, epistasis, and development
- Giovanni Sena — Plant Organs Regeneration : Measuring Self-Organization
- Hélène Delanoë-Ayari — Déplacement de cellules en 2 et 3 dimensions
- Jean-Paul Rieu — Collective migration in Dictyostelium
- Laurent Bonneviot — Approche bio-inspirée de l’Ingénierie moléculaire de surface en milieu confiné et conception de catalyseurs hétérogènes
- Laurent Bonneviot — reprogrammé le 15 juin
- Loïc Le Goff — The mechanics of a growing epithelium
- Maïté Coppey — Evidence of spatio-temporal fluctuations of supranucleosomal state regulating accessibility of bromodomain to acetylated H4 in living cells by high-resolution FLIM
- Manlio Vinciguerra — SIRT1 signaling and epigenetics during cellular stress
- Marie-Noëlle Prioleau — Control of the spatio-temporal program of DNA replication in vertebrates
- Nicolas Lartillot — Modèles probabilistes et chaînes de Markov Monte Carlo en évolution moléculaire.
- Pascale Lesage — Stress induced coregulation of Ty1 retrotransposon sense and antisense transcription
- Peter Meister — Putting things in place : sequences and signals for genome nuclear organization
- Peter R. Cook — A model for all genomes : the role of RNA polymerases fixed in specialized factories
- Philippe Bertrand — Delivery systems with HDAC inhibitors
- Saadi Khochbin — Molecular basis of post-meiotic male genome reprogramming : essential role for histone hyperacetylation and histone variants
- Véronique Rosilio — Molecular organized films of lipids, proteins and amphiphilic polymers : Application to innovative pharmaceutical systems.
- Vincent Colot — Multigenerational epigenetic variation : an epigenomics and quantitative genetics perspective
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Séminaires 2015
- Jose Paulo Farinha - Very bright, very stable : very useful
- Laurent Heux - Bioinspired materials obtained by self-assembling properties of elementary bricks : from the primary wall to the iridescence of beetle shells.
- Nouvel article
- Xiaobo Wang - Controlling mechanism of basal actomyosin oscillation during Drosophila ovary development
Rubrique : L’image du Mois
Articles et sous-rubriques :
Rubrique : Publications
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Rubrique : Intranet
Articles et sous-rubriques :
Rubrique : Annuaire
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Rubrique : Actualités
Articles et sous-rubriques :
